Term
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Definition
B cells, T cells, and NK cells |
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Term
Organized lymphoid Organs |
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Definition
Lymph nodes, thymus, spleen, tonsils, and adenoids |
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Term
Less organized lymphoid tissue |
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Definition
MALT, Bone Marrow, and Skin |
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Term
Location of B cells and T cells in lymph node |
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Definition
B cells - Cortex T cells - Paracortex |
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Term
Where are Leukemias based? What Hematopoietic lineage are they descended from? |
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Definition
Bone Marrow Any HP lineage |
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Term
Where are Lymphomas based? What HP lineage do they descend from? |
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Definition
Outside the Bone Marrow Lymhoid lineage |
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Term
Are leukemias and lymphomas clonal? |
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Definition
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Term
Difference between acute lymphoblastic leukemia and lymphoblastic lymphoma |
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Definition
Leukemia - See blasts in bone marrow and blood Lymphoma - blasts infiltrate thymus or nodes |
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Term
Acute vs Chronic Leukemia Cell maturity Clinical Course Age of Onset |
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Definition
Acute: Immature blasts, months, Kids and Adults Chronic: Mature, years, Adults |
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Term
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Definition
Granulocyte monocyte eosinophil basophil erythrocyte megakaryocyte |
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Term
Lymphoid vs Myeloid blasts morphology |
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Definition
Myeloid blasts are larger with more cytoplasm, more prominent nucleoli, +/- Auer rods Lymphoid blasts have little to no nucleoli and are smaller with scant cytoplasm |
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Term
What are Auer rods and what do they inidcate? |
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Definition
They are fused primary granules and indicate Acute Myelogenous Leukemia |
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