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305 exam3 lec. 3
n/a
12
Biology
Undergraduate 3
11/01/2013

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Term
stage one glycolysis-
Definition
Glucose →→→ 2 glyceraldehyde-3-phosphate (G3P)(uses 2 ATP)
Term
Step 1 glycolysis-
Definition
Glucose + ATP → G-6-P + ADP
6C->6C
Hexokinase
ATP-independent phospotransferase can also bring in G6P
Energy carrier: -ATP
Term
step 2 glycolysis-
Definition
G-6-P ↔ Fructose-6-P
6C->6C
Phosphoglucose isomerase
Term
step 3 glycolysis
Definition
Fructose-6-P + ATP → Fructose-1,6-bisphosphate + ADP
6C-> 6C
Phosphfructokinase
Energy Carrier: -1 ATP
Term
step 4 glycolysis
Definition
Fruc-1,6-2P ↔ Dihydroxyacetone phosphate (DHAP) + Glyceraldehyde-3-phosphate (G3P)
6C-> 3C +3C
Aldolase
Term
step 5 glycolysis
Definition
Dihydroxyacetone phosphate (DHAP) ↔ Glyceraldehyde-3-phosphate (G3P)
3C <-> 3C
Triose phosphate isomerase (TIM)
Term
step 6 glycolysis
Definition
G3P + NAD+ + Pi ↔ 1,3-bisphosphoglycerate + NADH + H+
3C<->3C
Glyceraldehyde 3 phosphate dehydrogenase
Energy carrier= +1NADH
Term
step 7 glycolysis
Definition
1,3-bisphosphoglycerate + ADP ↔ 3-phosphoglycerate (3PG) + ATP
3C<-> 3C
Phophoglycerate kinase
Energy carrier= +1ATP (substrate-level phosphorylation)
Term
step 8 glycolysis
Definition
3-phosphoglycerate (3PG) ↔ 2-phosphoglycerate (2PG)
3C<->3C
Phosphoglycerate mutase
Shift of phosphate functional group
Term
step 9 glycolysis
Definition
2-phosphoglycerate (2PG) → phosphoenolpyruvate (PEP) + H2O
3C<-> 3C
enolase
Term
step 10 glycolysis
Definition
Phosphoenolpyruvate (PEP) + ADP → pyruvate + ATP
3C<->3C
Pyruvate kinase
Energy carrier: +1ATP (substrate-level phosphorylation)
Term
STAGE 2 glycolysis
Definition
G3P → pyruvate (1NADH and 2 ATP per run) Stage 2 happens twice per glucose
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