Shared Flashcard Set

Details

A&P 2 - CH17 Blood
Chapter 17
86
Anatomy
Undergraduate 2
09/03/2008

Additional Anatomy Flashcards

 


 

Cards

Term
Thrombin is made up of:
Definition
Prothrobinase and Prothrombin
Term
Fibrin is made up of:
Definition
Thrombin and Fibrogen
Term
List an Anticoaglulant:
Definition
Asprin, Cumidin, Heparin
Term
What is a thromboembolytic disease?
Definition
A condition that causes undesireable clot formation. (clot too much)
Term
What is an example of a thromboembolytic disease?
Definition
Thrombus
Term
What are the the three main functions of blood?
Definition
Transportation, Regulation, Protection
Term
Name three things the blood transports.
Definition
Gasses, neutrients, waste products, hormones
Term
Name three things the blood regulates.
Definition
Temperature, Ph, electrolyte balance, fluid volume
Term
Name two Protective measures of blood.
Definition
Clotting, prevention of infection (WBCs)
Term
What is the normal percentages of plasma to formed elements?
Definition
55% plasma, 45% formed elements
Term
A hematicrit test is a test for?
Definition
Percentage of formed elements in blood.
Term
What is the percentage of water in plasma?
Definition
92%
Term
Name the four main plasma protiens(solutes)of plasma.
Definition
Albunims, Globulins, Enzymes, Fibrogens
Term
What are the three classes of Globulins and which one is not made in the liver?
Definition
Alpha, Beta & Gamma. Gamma not made in liver
Term
Why are transport protiens needed to tranport small particles (lipids)?
Definition
Without the attached protiens they would be filtered out by the kidney
Term
What produces Gamma Globulins?
Definition
Plasma cells
Term
What Plasma protien helps regulate osmotic presure?
Definition
Albunims
Term
What percentage of the plasma is made up of plasma protiens?
Definition
7%
Term
What plasma protien is responsible for clotting?
Definition
Fibrinogens
Term
Serum differs from Plasma because Serum is missing -
Definition
Clotting protiens (Fibrogens)
Term
What type of stem cell is the origin of blood formed elements?
Definition
Hemocytoblasts
Term
What type of stem cell becomes a RBC?
Definition
Erythroblast to Erythrocyte(RBC)
Term
What type of stem cell becomes a lymphocyte?
Definition
Lymphoid stem cell.
Term
Hemopoiesis is?
Definition
Formation of all blood formed elements
Term
Whatis the formation of platelets called?
Definition
Thrombopoises
Term
What is the formation of WBCs called?
Definition
Leukopoiesis
Term
What type of blood cells far outnumber all other blood cells?
Definition
RBCs
Term
On average, how many RBCs are in 1 cubic mm?
Definition
5 million
Term
What is the average lifespan of a RBC?
Definition
120 days
Term
The shape and diameter of a RBC is?
Definition
Bi-concave disk, 7.5 micro meters wide
Term
What are the advantage of the RBC shape?
Definition
More surface area and flexibility
Term
What cell elements do RBCs lack?
Definition
Nucleus, ribosomes, mytocondria
Term
What type of ATP production occurs in a RBC?
Definition
anerobic
Term
Hemoglobin comprimises what percentage of RBC?
Definition
95%
Term
What is the protien structure of a hemoglobin?
Definition
Quadrinary structure, 2 alpha, 2 Beta
Term
What is a heme group?
Definition
Nitrogen containing pigment that holds an iron ion
Term
What food contains B12?
Definition
Meat, eggs, and dairy products
Term
What happens after the first oxygen bonds to the iron in the heme?
Definition
The molecule changes shape to make it easyer for other oxygens to attach
Term
Where is CO2 carried in the hemoglobin and what is it then called?
Definition
Globin, Carbamino Hgb (20% carried this way)
Term
What percentage of RBCs hemalize at the end of thier life?
Definition
10%
Term
What happens to 90% of RBCs at the end of thier life?
Definition
They are phagosized by macrophages
Term
What part of the RBC is broken down into amino acids?
Definition
Globin
Term
What protien is the iron ion bound to after it is pulled out of the heme?
Definition
Transferrin.
Term
What is iron stored as in the liver?
Definition
Ferritin and Hemosiderin
Term
When RBCs are broken down, what is the cycle of nitrogen waste products?
Definition
Biliverdin, then unconjugated bilirubin, then conjigated bilirubin
Term
Where is unconjigated bilirubin turned into congigated bilirubin?
Definition
In the Liver
Term
Where does the majority of congigated bilirubin leave our body?
Definition
Through the small and then large intestine.
Term
What causes Jaundice?
Definition
High about of uncongigated bilirubin in the bloodstream
Term
What does the kidney do when it detects less oxygen in the blood?
Definition
It makes EPO
Term
What does EPO do?
Definition
If causes an increase in rate of RBC mytosis and rate of maturation
Term
How long does it take for a RBC to get into the bloodstream?
Definition
5-7 days
Term
Define Anemia
Definition
A decreased oxygen carrying capacity of the blood.
Term
An immature blood cell in the bloodstream is called a?
Definition
Reticulocyte
Term
Name 3 ways the blood's oxygen carrying capacity can be effected?
Definition
Decrease in # RBCs, Something wrong with hemoglobin, Genetic pre-disposition
Term
Name the two ways anemia can occur ?
Definition
Decreased number of RBCs, Something wrong with the hemoglovin.
Term
What can cause aplastic anemia?
Definition
Destruction of bone marrow
Term
What is needed to absorb B12?
Definition
Intrinsic Factor
Term
If there is not enough B12 then the cells won't divide, this is what type of anemia?
Definition
percicious
Term
Name two types of genetic anemias.
Definition
Thallasimia, and Cycle Cell
Term
What region of the world is predisposed for Thallasimia?
Definition
Mediterrnian
Term
What causes Cycle cell anemia?
Definition
1 pair of amino acids are reversed
Term
What is a condition of too many RBCs called?
Definition
Polycythemia
Term
What can cause polycythemia?
Definition
Something wrong with bone marrow, blood doping, injection of EPO
Term
What are bad side effects of polycythemia?
Definition
Increase in BP, Blood thickens
Term
What types of WBCs are granulocytes?
Definition
Basophils, Eosinophils, Neutrophils
Term
What type of WBCs are agranulocytes?
Definition
Monocytes, Lymphocytes
Term
On average, how many WBCs are in 1 cubic mm?
Definition
7,500
Term
Name three things common to all WBCs?
Definition
Diapedesis (can crawl out of vessels using amoebiod motion), Positive chemotaxis, Cell division
Term
What is the lifespan of WBCs?
Definition
few hours to years
Term
What WBCs can do phagocytosis?
Definition
Neutrofils, eosiniphils, monocytes.
Term
Put the 5 WBCs in order from most previlant to least.
Definition
Neutrophils, Lymphocytes, Monocytes, Eosiniphils, Basophils
Term
Name a dissorder of WBCs?
Definition
Leukemia.
Term
If a test revieled a 11,000 + WBC count, what would you suspect?
Definition
Leukemia
Term
What is Leukopeoisis regulated by?
Definition
Hormone called cytokines (Colony stimulating factor)
Term
What could be used to treat a cancer patient who has a low RBC and WBC?
Definition
CSF and EPO
Term
Name two iron Hemoglobin caused anemias.
Definition
Iron Deficency anemia and Pernicious anemia
Term
Cancer, radiation, bacteria or toxins can cause what type of anemia?
Definition
Aplastic anemia
Term
Hemolytic anemia can be caused by what three things?
Definition
Transfusions, Bacteria and parasites
Term
Blood loss can lead to ______________ anemia.
Definition
Hemorrhagic Anemia
Term
Myloid stem cells become Red and White blood cells except for __________.
Definition
lymphocytes
Term
What basic products are needed to produce RBCs?
Definition
Amino Acids, Iron, B12, B6
Term
What type of WBCs can live for decades?
Definition
Lymphocytes
Term
Specific immunity is given by ________________ WBCs.
Definition
Lymphocytes
Term
Platelet formation is called?
Definition
Thrombopoeisis
Term
_________________ stem cells become Lymphocytes?
Definition
Lymphoid.
Term
Name three types of Anemia caused by a decreased number of RBCs
Definition
hemorragic, hemolytic, aplastic
Supporting users have an ad free experience!