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sensory receptors (CNS); external stimuli (light, sound, touch, heat, smell, and taste); internal stimuli (blood pressure, blood CO2, muscle tension, etc...) |
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neurons--> neurons (integrate sensory input) |
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CNS-->effector cells (muscle or endocrine cells) |
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central nervous system (CNS) |
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brain and spinal cord; integrates information |
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peripheral nervous system (PNS) |
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nerves that connect CNS to rest of animal's body |
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functional unit of nervous system that transmits information throughout body |
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contains nucleus ans cellular organelles of the neuron |
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fiberlike processes specialized to receive input from other neurons |
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fiberlike processes specialized to conduct infomation toward synapse |
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conical region of axon that joins the cell body |
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insulating layer surrounding the axons of some neurons |
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site at the end of axons where neurotransmitters are released |
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narrow gap between syanptic terminal and effector cell |
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transmitting cell at a synapse |
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the target cell of a synapse |
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chemical messengers of the nervous system |
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supporting cells that assist, structurally support, protect, and insulate neurons |
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provide structural and metabolic support |
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naturally occurring barrier created by the modification of brain capillaries (as by reduction in fenestration and formation of tight cell-to-cell contacts) that prevents many substances from leaving the blood and crossing the capillary walls into the brain tissues |
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form tracks along which neurons migrate (developing embryo) |
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voltage difference accrose the plasma membrane of a cell |
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membrane potential of inactive neuron |
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resulting membrane potential that would arise if membrane were permeable to one ion alone (represents point at which electrical gradient exactly balances concentration gradient) |
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always open (responsible for resting potential) |
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open or close in response to one of three stimuli |
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stretch-gated ion channels |
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respong to mechanical deformation of membrane |
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ligand-gated ion channels |
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respond to specific chemcicals (e.g. neurotransmitter) |
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voltage-gated ion channels |
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respond to changes in membrane potential |
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capable of generating large changes in their membrane potentials (due to opening and closing of gated ion channels) |
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membrane voltage becomes less negative (e.g. opening of Na+ channels) |
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membrane voltage becomes more negative (e.g. opening of K+ channels) |
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magnitude of hyperpolarization of depolarization varies with strength of stimulus |
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an all-or-none electrical event that propagates down axons |
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short interval following an action potential during which axon cannot be stimulated to fire another action potential |
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rapid transmission of a nerve impulse along an axon, resulting from the action potential jumping from one node of the Ranvier to another, skipping the myelin-sheathed regions of the membrane |
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separates presynaptic and postsynaptic cell |
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junction where one neuron communicates with another ell across a narrow gap; neurotransmitter molecules released by the neuron diffuse across the synapse, relaying messages to the other cell |
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membranous sac containing neurotransmitter molecules at the tip of an axon |
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moleculte that is released from the synaptic terminal of a neuron at a chemical synapse, diffuses across the synaptic cleft and binds to the postsynaptic cell, triggering a response |
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direct synaptic transmission |
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chemical synapse in which neurotransmitter opens ligand-gated ion channels in postsynaptic cell that changes this cell's membrane voltage directly |
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excitatory postsynaptic ptotential (EPSP) |
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causes postsynaptic cell to depolarize (drives membrane potential towards threshold) |
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potential that an excitable cell membrane must reach for an action potential to be initiated |
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ihibitory postsynaptic potential (IPSP) |
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causes postsynaptic cell to hyperpolarize (drives membrane potential away from threshold) |
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ADDITIVE effect of EPSPs and IPSPs |
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additive of effects of PSPs from single synapse (repetition adding, single note) |
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additive effects of PSPs from multiple synapses (multiple adding, chord) |
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indirect synaptic transmission |
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neurotransmitter binds to a receptor other than an ion channel |
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released at neuromuscular juctions (skeletal muscles); neurotransmitter |
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affects sleep, mood, attention, and motor skills; neurotransmitter |
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affects sleep and mood; neurotransmitter |
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inhibitory neurotransmitter |
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inhibitory neurotransmitter |
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excitatory neurotransmitter |
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excitatory neurotransmitter |
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mediates pain perception; neurotransmitter |
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natural analgesics; neurotransmitter |
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