Shared Flashcard Set

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Addiction
Drug Abuse and Stimulants
28
Medical
Graduate
04/10/2010

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Cards

Term
Methadone
Definition
replacement strategy for narcotics
Term
buprenorphine
Definition
replacement strategy for narcotics
Term
acamprosate
Definition
replacement strategy for alcohol
Term
varenicline
Definition
replacement strategy for nicotine
Term
bupropion
Definition
DA uptake inhibitor: used for nicotine
Term
Naltrexone
Definition
Antagonist strategy for alcohol
Term
Rimonabant
Definition
CB-1 antagonist for alcohol and narcotics
Term
methylphenidate is a
Definition
psychostimulant
Term
Khat (cathinone) is a
Definition
psychostimulant
Term
cocaine, amphetamine, methamphetamine are
Definition
psychostimulants
Term
Mechanism of psychomotor stimulant action by cocaine is via
Definition
blocking Monoamine transporters
Term
Mechanism of psychomotor stimulant action by Amphetamine, Methamphetamine,Methylphenidate, ephredine is via
Definition
reverse efflux and competitive inhibition of uptake of monamines
Term
which endogenous monoamine affects:
reinforcement, locomotor stimulation, anorexia, hyperthermia?
Definition
dopamine
Term
which endogenous monoamine affects:
arousal, attention, anorexia, hyperthermia?
Definition
Norepinephrine
Term
which endogenous monoamine affects:
anorexia, hyperthermia, blunts reward?
Definition
Serotonin
Term
Stimulant action of ephedrine is by
Definition
blocking NE transporter
Term
Mechanism of action of cathinone is via
Definition
blocking DA transporter
Term
cocaine acts via blocking the transporter for the following monamines:
Definition
NE = DA = 5HT
Term
Amphetamine acts via blocking the transporter for the following monamines:
Definition
NE = DA > 5HT
Term
Methlphenidate acts via blocking the transporter for the following monamines:
Definition
DA > NE
Term
Cathinone acts via blocking the transporter for the following monamines:
Definition
DA
Term
Ephedrine acts via blocking the transporter for the following monamines:
Definition
NE
Term
which psychostimulant drug also binds Na+ channels and have local anesthetic actions that contribute to seizures in overdose?
Definition
cocaine
Term
5HT2A/5HT2C agonists are
Definition
hallucinogens. (eg LSD, Mesacaline, Psilocybin)
Term
Dronabinol
Definition
medical use of marijuana (synthetic THC in pill form) for u se in emesis associated w cancer chemo
Term
indolealkylamines are hallucinogens tt are structurally related to serotonin. They include:
Definition
LSD, N,N-dimethyltryptamine, psilocin,psilocybin, DMT
Term
Hallucinogens that are amphetamine derivatives include:
Definition
Mescaline, MDMA, DOM, Myristin elemeicin
Term
how does caffeine work?
Definition
by inhibiting adenosine receptors. these receptors are inhibitory and cause sedation, sleep
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