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Alessandra Della Davis
Module 03 Molecular and Cellular Radiation Biology Review
20
Biology
Not Applicable
02/23/2022

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Term
Genetic effects
Definition
Effects upon future generations due to the irradiation of germ cells in previous generations.
Term
Epilation
Definition
hair loss (also called alopecia) is caused by exposure to radiation since hair follicles are growing tissue.
Term
Desquamation
Definition
shedding of the outer layer of the skin occurs at higher radiation doses. Manifests first as moist skin peeling, and then a dry skin flaking may develop.
Term
Meiosis
Definition
A special type of cell division that reduces the number of chromosomes in each daughter cell to half the number of chromosomes in the parent cell.
Term
Relative biologic effectiveness (RBE)
Definition
describes the comparative capabilities of radiation with differing LETs to produce a particular biologic reaction.
Term
Oxygen Enhancement Ratio (OER)
Definition
Oxygen effect refers to the enhancement of the therapeutic or detrimental effect of ionizing radiation due to the presence of oxygen.
Term
Linear energy transfer (LET)
Definition
The average energy deposited per unit length of the track. Calculated by dividing the total energy deposited in the medium by the total length of the track.
Term
Cell survival curve
Definition
A classic method of displaying the sensitivity of a particular type of cell to radiation.
Term
Mapping
Definition
Process of locating and identifying the genes in the genome.
Term
Protoplasm
Definition
The chemical building material for all living things.
Term
Anaphase
Definition
The phase of mitosis during which the centromeres are severed and the sister chromatids move apart and are subsequently pulled toward opposite poles of the mitotic spindle.
Term
Cytoplasmic organelles
Definition
What all the miniature cellular components present in the cytoplasm of the cell are referred to as
Term
Deoxyribose
Definition
A five-carbon sugar molecule
Term
Ribosomal RNA
Definition
Functions to assist in the linking of messenger RNA to the ribosome to facilitate protein synthesis
Term
Interphase
Definition
The brief time of cell growth that occurs just before mitosis
Term
Radiation biology
Definition
Branch of biology concerned with the effects of ionizing radiation on living systems
Term
Molecular damage
Definition
Injury on the molecular level resulting from exposure to ionizing radiation
Term
Target theory
Definition
Hypothesis that when a vital macromolecule such as DNA is directly or indirectly inactivated by exposure to radiation, the cell will die.
Term
Direct action
Definition
Biologic damage that occurs as a result of ionization of atoms on essential molecules produced by an immediate interaction with incident radiation
Term
Indirect action
Definition
a multistage process that first involves the production of reactive free radicals that are created by the interaction of radiation with water (H2O) molecules
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