Term
Acetylcholinesterase inhibitors
-drugs
-side effects |
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Definition
Drugs:
Tacrine
Galantamine
Donepezil
Rivastigmine
Side effects:
- anorexia, N & V, dyspepsia
- diarrhea
- weight loss
- muscle weakness/cramps
- dizziness
- insomnia |
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Term
Memantine
-mechanism
-side effects |
|
Definition
Mechanism:
- uncompetitive blockade of NMDA receptors
- prevents excitotoxicity and neuron death
- in theory, preserves nerves
Side effects:
- dizziness
- headache
- constipation
- confusion |
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Term
Treating depression in AD patients
-medications/classes |
|
Definition
SSRI's:
- sertraline (Zoloft)
- paroxetine (Paxil) |
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Term
Treating Agitation in AD patients
-medications/classes |
|
Definition
Benzodiazepines:
- lorazepam (Ativan)
Atypical Antipsychotics:
- risperidone (Risperadal)
- Olanzapine (Zyprexa)
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Term
Treatment of sleep disturbances in AD patients
-medications/classes |
|
Definition
Trazodone (Desyrel)
Short acting benzodiazepines:
- lorazepam |
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Term
Treatment of Anxiety in AD patients
-medications/classes |
|
Definition
Trazodone
Buspirone
Atypical antipsychotics:
- risperidone
- olanzapine |
|
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Term
Treatment of "sundowning" in AD patients
-medication |
|
Definition
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Term
|
Definition
- Antihistamine
- blocks action of amyloid
- some NMDA effects
- heals mitochondrial pores
- not known how it helps Alzheimers
- used in Russia but may become used in USA due to promising results
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