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Anatomy and Physiology BIO 201
Exam 4- Muscles
93
Biology
Undergraduate 1
04/14/2012

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Term
Functions of muscles
Definition
Movement, stability, control of body openings and passages, heat production
Term
Endomysium
Definition
thin sleep of loose connective tissue that surround each muscle fiber
Term
perimysium
Definition
thicker connective tissue sheath that wraps muscles fibers together in buddies called fascicles
Term
Epimysium
Definition
Fibrous sheath that surrounds the entire muscle
Term
Fasia
Definition
sheet of connective tissue that separates neighboring muscles or muscle groups form each other and from the subcutaneous tissue.
Term
indirect attachment
Definition
the muscle ends conspicuously short of its bony destination
Term
tendon
Definition
fibrous band or sheet attaching muscle to bone
Term
direct attachment
Definition
little separation between muscle and bone to the make eye
Term
prime mover
Definition
muscle that produces most of the force during a particular joint action
Term
synergist
Definition
muscle that aids the prime mover
Term
antagonist
Definition
muscle that opposes the prime mover
Term
fixator
Definition
muscle that prevents a bone from moving
Term
intrinsic muscle
Definition
entirely contained within a particular region
Term
extrinsic muscle
Definition
acts upon a designated region but has its origin elsewhere
Term
sarcolemma
Definition
plasma membrane of a muscle fiber
Term
sarcoplasm
Definition
cytoplasm in sarcolemma occupied by long protein odds (myofibrils)
Term
myoblasts
Definition
embryonic development of muscle fiber
Term
Function of satellite cells in muscles
Definition
If injured, the cells can multiply and produce new muscle fibers to a degree.
Term
The parasympathetic division.....
Definition
Responsible for hear rate, gland secretions, and the relaxation response after stimulation
Term
Two types of cholinergic receptors
Definition
nicotinic receptors and muscarinic receptors
Term
Nicotinic receptors
Definition
all excited by ACh, ANS ganglia, adrenal medulla, skeletal muscle
Term
Muscarinic Receptor
Definition
some cells excited, others inhibited (excite intestine but inhibit cardiac), gland , smooth muscle and cardiac muscle
Term
When the parasympathetic divisions stimulate, what neurotransmitter is real ease at the effector organ?
Definition
acetylcoline is the post synaptic neurotransmitter released
Term
When norepinephrine binds to beta-adrenergic receptors on bronchioles (air tubes in lungs), is it most likely binding to _____ receptors.
Definition
ACH receptores
Term
During a fight or flight response, which type of receptor on the pilioerector muscle responds to the released neurotransmitter?
Definition
B2 receptors
Term
Correctly ordered pathway of nerve transmission taking place in the body when running away?
Definition
Term
Meth Mouth
Definition
stimulates SNS, bruxism, poor oral hygiene, hyposalivation
Term
Is dual innervation by SNS and PNS always necessary?
Definition
Term
Fx of Cerebral cortex
Definition
limbic system connects conscious thoughts with hypothalamus
Term
Fx of Hypothalamus
Definition
major controller of visceral motor system (hunger, thirst, temp reg., emotions, etc)
Term
How many skeletal muscles re in the human body?
Definition
Over 600
Term
Ture or False: Skeletal muscles are voluntary and require conscious stimulation.
Definition
True
Term
What are the two points of attachment in skeletal muscles?
Definition
Origin and insertion
Term
fascicles
Definition
Term
What are the characteristics of muscle tissue?
Definition
excitability (responsiveness), conductivity, contractility, extensibility, elasticity.
Term
What bands of muscles are dark bands? Light bands?
Definition
Dark bands: Anisotropic (A) bands
Light bands: Isotropic (I) bands
Term
Where is the H band?
Definition
middle of A band; thick filaments only
Term
Where is the M line?
Definition
middle of H band
Term
Characteristics of I band
Definition
alternating lighter bands; stands for isotropic
Term
Fx of Z disc
Definition
provides anchorage for thin filaments and elastic filaments
(bisects I band)
Term
Sacromere
Definition
segment from Z disc to Z disc
(functional contractile unit of muscle fiber)
Term
WHy do muscle cells shorten ?
Definition
Because their individual sarcomeres shorten
Term
What three myofilaments are found in myofibrils?
Definition
Thick, thin, and elastic filaments.
Term
What are the contractile proteins?
Definition
myosin and actin
Term
What are the regulatory proteins?
Definition
Tropomysin and troponin
Term
What determines calcium availability?
Definition
Sarcoplasmic reticulum, terminal cisternae, and t tubules (triad)
Term
What happens when nerve connections are severed or poisoned?
Definition
the muscle is paralyzed
Term
Denervation atrophy
Definition
Shrinkage of paralyzed muscle when connection not restored
Term
Somatic motor neurons
Definition
nerve cells whose ell bodies are in the brainstem and spinal cord that serve skeletal muscle
Term
Somatic motor fibers
Definition
their axons that lead to the skeletal muscle
-each nerve fiber branches out to a number of muscle fibers
-each muscle fiber is supplied by only one motor neuron
Term
Motor Unit
Definition
one nerve fiber and all the muscle fibers innervated by it
Term
Characteristics of muscle fibers of one motor unit
Definition
-dispersed throughout the muscle
-contract in unison
-produce weak contraction over wide area
-provides ability to sustain long term contraction as motor units take turns contracting (postural control)
-effective contraction usually requires the contraction of several motor units at once
Term
An average motor unit consists of how many muscle fibers?
Definition
200 muscle fibers for each motor unit
Term
Small motor units have what kind of control
Definition
fine degree control (eye and hand muscles)
Term
Small motor units have how many muscle fibers per neuron?
Definition
Three to six
Term
Large motor units have what control?
Definition
more strength than control, many muscle fibers per motor unit
Term
Large motor units have how many muscle fibers per neuron?
Definition
powerful contraptions supplied by large motor units (example: gastrocnemius has 1000 muscle fibers per neuron)
Term
synapse
Definition
point where a nerve fiber meets its target cell
Term
Synaptic knob
Definition
swollen end of nerve fiber
Term
The synaptic knob contains what?
Definition
Contains synaptic vesicles filled with acetylcholine (ACh)
Term
Synaptic cleft
Definition
tiny gap between synaptic knob and muscle sarcolemma
Term
What do schwann cells do with NMJ?
Definition
the cell envelops and isolates all of the NMJ from surrounding tissue fluid
Term
synaptic vesicles undergo what?
Definition
exocytosis releasing ACh into synaptic cleft
Term
How many ACH receptors are incorporated into muscle cell plasma membrane?
Definition
50 million ACh receptors- proteins incorporated into muscle cell plasma
Term
Basal lamina
Definition
thin layer of collagen and glycoprotein separates Schwann cell and entire muscle cel from surrounding tissues
-contains acetylcholinesterase (AChE) that breaks down ACh after contractions causing relaxation
Term
Effets of pesticides that contain cholinesterase
Definition
-bind to AChE and prevent it form degrading ACh
Term
Spastic paralysis
Definition
a state of continual contraction of the muscles; possible suffocation
Term
Tetanus (lockjaw)
Definition
form of spastic paralysis caused by toxin Clostridium tetani
Term
Flaccid paralysis
Definition
a state in which the muscles are limp and cannot contract
Term
Botulism
Definition
type of food poisoning caused by a neuromuscular toxin secreted by the bacterium Clostridium botulinum
Term
How does botulism effect the body? (physiology of sickness)
Definition
blocks release of ACh causing flaccid paralysis
Term
The specific part of the sacromere structure that is only occupied by thick filaments and is lighter in color that the rest of that particular band is called the _____.
Definition
H zone
Term
Four major phases of contraction and relaxation
Definition
excitation, excitation- contraction coupling, contraction, relaxation
Term
Phases of contraction: excitation
Definition
the process in which nerve action potentials lead to muscle action potentials
Term
Phases fo contraction: excitation- contraction coupling
Definition
events that link the action potentials on the sarcolemma to activation of the myofilaments, thereby preparing them to contract
Term
Phases of contraction: contraction
Definition
step in which the muscle fiber develops tension and may shorten
Term
Phases fo contraction: relaxation
Definition
when its work is done, a muscle fiber relaxes and returns to its resting length
Term
What happens in excitation?
Definition
-nerve signal opens volatage-gated calcium channels in synaptic knob
-Ca stimulates exoyctosis of ACh from synaptic vesicles
-ACh released into synaptic cleft
Term
During excitation, what binds to each receptor protein? What does it cause?
Definition
two ACh molecules, opens Na+ and K+ channels
Term
What happens in excitation- contraction coupling?
Definition
-action potential speeds down into T tubules
-opens votage-gated ion channels in t tubules and Ca+2 cahnnels in SR
-Ca+2 enters the cytosol
Term
During expiation- contraction coupling, what does Ca bind to?
Definition
troponin in the thin filaments
Term
What happens during relaxation?
Definition
-nerve stimulation and ACh release stop
-AChE breaks down ACh and fragments reabsorbed into synaptic knob
-stimulation by ACh stops
Term
What makes a contraction strong?
Definition
length-thension relation ship (optimal overlap) and cross-sectional area force relationship
Term
Where do muscles get ATP?
Definition
anaerobic fermentation and aerobic respiration
Term
When a muscle is at rest, which of the following is not associated chemically with the others?
-actin
-myosin
-troponin
-tropomyosin
-two of these
Definition
tropomyosin blocks ACh receptors.
Term
What kinds of smooth muscles are there?
Definition
multi-unit and single-unit(visceral muscle)
Term
Isometric contraction
Definition
muscle contraction without appreciable shortening or change in distance between its origin and insertion.
Term
isotonic contraction
Definition
muscle contraction without appreciable change in the force of contraction; the distance between the muscle's origin and insertion becomes lessened
Term
Concentric
Definition
contraction resulting in shortening of a muscle, used to perform positive work or to accelerate a body part. It is metabolically more demanding than an eccentric contraction. Called also shortening contraction.
Term
Eccentric contraction
Definition
contraction in the presence of a resistive force that results in elongation of a muscle, used to perform negative work or to decelerate a body part. It is less metabolically demanding than a concentric contraction but may cause disruption of associated connective tissue with delayed soreness or frank injury if it occurs in an unaccustomed manner. Called also lengthening contraction.
Term
______surrounds each muscle fascicles, whereas_______surrounds each muscle fiber.
Definition
Perimysium, endomysium
Term
The enlarged areas of the sarcoplasmic reticulum near the T tubules are the______
Definition
terminal cisternae.
Term
Draw a sacromere and label these.... A band, I band, H zone, Z line (AKA A disc), titian, thin and thick filament.
Definition
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