Term
What is integument system composed of?
What is skin (largest organ) composed of? |
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Definition
the skin & its accessory stuctures
-skin is two regions: epidermis and dermis |
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Term
| what tissue mostly composes the epidermis? |
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Definition
| stratified squamous epithelium |
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Term
| what do most cells in epidermis produce? |
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Definition
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Term
| how does new cell production in skin occur? |
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Definition
mitosis
-deeper layer or epidermis (stratum basale)
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Term
| What happens to surface skin cells? |
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Definition
| die and desquamate (filled with keratin) |
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Term
what strata is the epidermis comprised of?
what "layers" are they referred to?
how many layers of cells on each strata? |
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Definition
-stratum corneum (hard layer) 20-30 layers
-stratum lucidum (clear layer) 2-3 layers
-stratum granulosum (granular layer) 3-5 layers
-stratum spinosum (spiny layer) 5-7 layers
-stratum basale (basal layer) 1 layer
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Term
Stratum Corneum
which layer?
how many layers? with what in them?
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Definition
-most superficial "hard" layer
-20-30 layers of dead cells filled with keratin
-layer has waterproofing glycolipids (produced in granulosum) |
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Term
where are glycolipids found? produced?
what is purpose? |
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Definition
found in stratum corneum, produced in stratum granulosum
-purpose is waterproofing |
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Term
Stratum Lucidum
how many layers? made of what?
where is layer present? |
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Definition
-"clear" layer of 2-3 layers of dead cells filled with keratin
-layer present only in "thick skin" in bottoms of feet/palms of hands |
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Term
Stratum Granulosum
how many layers?
contains what? |
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Definition
-"granular" made of 3-5 layers of cells that are alive but organelles are degenerating
-contains 2 types of granule producing cells: keratinocytes and lamellar bodies |
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Term
what are keratinocytes?
what do they produce? |
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Definition
granule-producing cells found in stratum granulosum
-produce keratohyalin granules that secrete keratin
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Term
| what are keratohyalin granules? |
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Definition
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Term
| What are lamellar bodies? |
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Definition
type of granule-producing cells
-produce lamellated granules that secrete glycolipids found in stratum corneum |
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Term
what secretes glycolipids?
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Definition
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Term
Stratum Spinosum
how many layers?
contains what? |
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Definition
-"spiny" 5-7 layers of living cells
-contains melanin granules that are produced in basale layer
-contains Langerhan's cells |
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Term
melanin comes from where?
found where? |
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Definition
comes from melanocytes produced in stratum basale
-found in stratum spinosum |
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Term
where are Langerhan's cells derived from?
found where? |
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Definition
from the immune system & migrate from bone marrow
found in stratum spinosum |
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Term
Stratum Basale
how many layers?
contains what? |
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Definition
-"basal" 1 layer of rapidly dividing epithelial cells that migrate to superficial layers
-contains melanocytes (produce melanin found in stratum spinosum) and merkel discs (touch receptors |
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Term
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Definition
| touch receptors, found in stratum basale |
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Term
| which strata have living cells? |
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Definition
-stratum basale
-stratum spinosum
-stratum granulosum (alive, but their organelles -are degenerating) |
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Term
| which strata have dead cells? |
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Definition
-stratum corneum
-stratum lucidum |
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Term
where are these found:
keratin?
melanin?
Lamellar bodies?
merkel discs?
keratinocytes?
lamellated granules?
glycolipids?
mitosis? |
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Definition
1) keratin-stratum corneum, lucidum, made in granulosum
2) melanin- spinosum, made in basale
3) lamellar bodies- granulosum
4) merkel discs- basale
5) keratinocytes- granulosum
5) lamellated granules- granulosum
6) corneum, made in granulosum
7) mitosis-basale
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