Term
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Definition
Direct cholinomimetic agonist. Post-operative and neurogenic ileus and urinary retention. |
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Term
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Definition
Directh cholinomimetic agonist. Glaucoma. |
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Term
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Definition
Direct cholinomimetic agonist Potent stimulator of sweat, tears, saliva. |
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Term
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Definition
Direct cholinomimetic agonist. Challenge test for Dx of asthma. Causes bronchoconstriction. |
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Term
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Definition
AChE inhibitor. Post-op and neurogenic ileus and urinary retention, MG, reversal of NMJ in anesthesia |
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Term
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Definition
AchE inhibitor. Myasthenia gravis. |
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Term
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Definition
AchE inhibitor. Dx of myasthenia gravis. |
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Term
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Definition
AchE inhibitor. Glaucoma Atropine-overdose |
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Term
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Definition
AchE inhibitior. Glaucoma |
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Term
Parathion and organophosphate poisoning. What are the Sx and Tx? |
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Definition
Sx: Diarrhea, Urination, Miosis, Bronchospasm, Bradycardia, Excitation of skeletal muscle and CNS, Lacrimation, Sweating, Salivation Tx: atropine and pralidoxime |
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Term
Atropine, homatropine, tropicamide, cyclopentolate Use? |
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Definition
Muscaranic antagonist Produces mydraisis and cycloplegia in eye. |
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Term
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Definition
Cholinoreceptor blocker Parkinson's disease, dystonia from neuroleptics |
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Term
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Definition
Cholinoreceptor blocker Motion sickness. |
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Term
|
Definition
Cholinoreceptor blocker Asthma, COPD |
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Term
Methscopolamine, oxybutin, glycopyrrolate Use? |
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Definition
Cholinoreceptor blocker Redce hypermobility in GI, reduce urgery and incontinence |
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Term
Tubocurarine, pancuronium Use? |
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Definition
Antagonist at NMJ. Anesthesia Overcome with AchEI like neostigmine, edrophonium, etc. Given with glycopyrrolate to avoid SLUD effects |
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Term
What plant extract mimics atropine-toxicity? |
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Definition
Belladona plant extract from Jimson weed plant. Note: SLUD seen from muscarine or clitocybe dealbata mushroom |
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Term
Epinephrine Which receptors does it affect? |
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Definition
| alpha 1, alpha 2, beta 1, beta 2 |
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Term
Norepinephrine Which receptors does it affect? |
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Definition
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Term
| Norepinephrine is converted to epinephrine by what enzyme? |
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Definition
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|
Term
Isoproterenol Acts at which receptors? |
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Definition
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Term
Dopamine Acts at which receptors? |
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Definition
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|
Term
Dobutamine Acts at which receptors? |
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Definition
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|
Term
Phenylephrine Acts at which receptors? |
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Definition
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|
Term
Terbulatine, albuterol Acts at which receptors? |
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Definition
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|
Term
Phenoxybenzamine, phentolamine MOA? |
|
Definition
Non-selective blocker of alpha 1 & 2 Phenoxybenzamine is irreversible Phentolamine is reversible |
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Term
|
Definition
Selective alpha 1 blocker. Use in hypertension and urinary retention in BPH. |
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Term
|
Definition
Selective alpha 2 blocker. Used in depression. May increase cholesterol. |
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Term
| What are the non-selective beta blockers? |
|
Definition
Propranolol, timolol, nadolol, pindolol, labetalol |
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Term
| What are the selective beta 1 blockers? |
|
Definition
Acebutolol Betaxolol Esmolol Atenolol Metoprolol |
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Term
p450 inducer or inhibitor? Quinidine |
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Definition
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Term
p450 inducer or inhibitor? Barbiturates |
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Definition
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Term
p450 inducer or inhibitor? Phenytoin |
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Definition
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Term
p450 inducer or inhibitor? Rifampin |
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Definition
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Term
p450 inducer or inhibitor? Griseofulvin |
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Definition
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|
Term
p450 inducer or inhibitor? St. John's wort |
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Definition
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Term
p450 inducer or inhibitor? Isoniazid |
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Definition
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Term
p450 inducer or inhibitor? Sulfonamides |
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Definition
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Term
p450 inducer or inhibitor? Cimetidine. |
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Definition
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Term
p450 inducer or inhibitor? Ketoconazole |
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Definition
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Term
p450 inducer or inhibitor? Erythromycin |
|
Definition
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Term
p450 inducer or inhibitor? Grapefruit juice. |
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Definition
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