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– A conceptual framework for understanding a body of evidence Evolution is a paradigm, as the process correctly predicts A LOT of things. |
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Greek influences in the thoughts of man's origin |
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Plato and Aristrole. Hierarchical organization of beings.
Humans at top Logos Great chain of being. |
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concept of God's strict and natural hierarchical structure of the universe.
God, angels, man, animals, plants, rocks. |
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Origins ca. 3.7 billion yrs Bacteria and blue-green algae Single-celled No |
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Origins ca. 1.2 billion yrs Higher organisms Structurarlly complex Have a nucleus Plasma membrane holding DNA |
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Eukaryotic Cell Membrane (look at pic on slide, too) |
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Outer cover of a cell Protects the internal parts Tranports molecules |
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Houses hereditary information DeoxirinboNucleic Acid (DNA) RiboNucleic Acid (RNA) |
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Semi-fluid material Contains structures involved in cell function |
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produce energy, contain mtDNA |
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mtDNA (located in the mitochondria) |
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Distinct from DNA, shorter, different structure, encodes proteins for mitochondria membrane present in egg, not in sperm |
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Increases surface area for metabolic reactions |
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Composed of proteins and RNA, location of protein manufacture |
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cellular components of body tissue (skin, bones, brain, nerves muscle) |
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undifferentiated cells in a fetus that can be induced to develop into any type of somatic cell |
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Gametes. What are the two types? What are their function? |
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sex cells. eggs cells and sperm cells. Sperm cells have no mitochondria. Function: join with gametes of the opposite sex, combine genetic information and make zygote which is a new individual. This is genetic informrataion in DNA in the form of chromosomes |
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What did Watson, Crick, Wilkins and Franklin do in 1953? |
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Structural and functional model of DNA, double helix. Form is ideal for replication and protein synthesis |
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What three parts make up the structure of DNA? What are these three parts together called? |
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Three parts: phosphate, sugar, base.
Together = nucleotide |
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Explain the structure of DNA...the four base pairs, what do they form together to make? |
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Adenine, Thymine, Guanine and Cytosine (A T G C) join together into hydrogen bonds. Sequences of bases form our genetic code. |
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Explain the process of DNA replication |
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the weak hydrogen bonds separate, new nucleotides attach themselves to available nucleotides resulting in two copies. |
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What is an Enzyme DNA polymerase I? |
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a complex protein that is a catalyst for chemical reactions |
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Complex molecules formed of chains of amino acids (polypeptides) |
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another word for amino acid? |
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what do proteins function as? Five functions. |
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Structural molecules tranport molecules - hemoglobin antibodies enzymes - catalysts hormones |
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What are proteins made from? |
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Explain the key concepts of amino acids: How many base pairs? How many possible combinations? How many amino acids are there? |
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3 base pairs, 64 possible combinations, 20 amino acids. Codon. |
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tri-nucleutodie sequences of base pairs. (A C G) |
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the process of transcribing DNA nucleotide sequence information into RNA sequence information |
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Transcription, whats RNA got to do with it? |
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RNA is single stranded with a similar structure to DNA only substitutes the U for T. RNA is formed at the exposed site. |
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what does mRNA do in transcription? |
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m (messanger) RNA separates and leaves the nucleus and enters the cytoplasm |
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What is the process of translation? |
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Translation is the production of proteins by decoding mRNA produced in transcription. mRNA to ribosomes. Each codon is read. tRNA brings corresponding Amino Acid |
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What happens next in translation? |
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reads codons sequentially, second amino acid attaches to the first, forms an amino acid chain. |
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Chromatin is the complex combination of DNA, RNA, and protein that makes up chromosomes. |
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what does DNA do in cell division? |
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DNA is uncoiled into strands in the nucleus. (chromatin) During cell division DNA coils up into discrete structures held together with supporting proteins (chromosomes) |
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A centromere is a region of DNA typically found near the middle of a chromosome where two identical sister chromatids come in contact. It is involved in cell division as the point of mitotic spindle. |
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Karyotoype of a somatic cell. How many pairs of homologous chromosomes? What is the diploid number? what is the haploid number? |
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There are 46 chromatids, this is the diploid number. Sex cells have half this, or the haploid number. |
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An autosome is a chromosome that is not a sex chromosome – that is to say there are an equal number of copies of the chromosome in males and females. |
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Genes. What are the made of? what are. Where are they found? |
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A fundamental unit of heredity. Made from a sequence of bases of DNA. Found on a specific spot on a chromosome called a locus. |
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a specific spot on a chromosome where genes are found. |
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Differenet versions of genes |
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cell division of zygote, growth, repair, and replacement of somatic cells.
Cells divide -chromosomes duplicate -duplicate cells seperate - cell divides into two daughter cells which are diploid (46). |
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Production gametes. Two divisions. Chromosomes replicate. Homologous pairs separate...crossing nover, recombination. Then there is the second division.
Gametes are non-identical haploids. |
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Exchange of genetic material between homologous chromosomes during the first phase of meiosis; mechanism for recombination |
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Rearrangement of genes on homologous chromosomes during meiosis Source of variation arising from sexual reproduction |
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Mitosis. How many cell divisions, how many daughter cells? Produces what kinds of cells? Genetically identical? What kind of cells produced? |
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1 cell division, 2 daughter cells, produces diploid cells, genetically identical, produces somatic cells. |
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Meiosis. How many cell divisions? How many daughter cells? What kinds of cells? Genetically identical? Produces what? |
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2 cell divisions, 4 daughter cells, produces haploid cells, not genetically identical, produces gametes |
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The genetic make-up of an individual |
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The physical expression of the traits in an individual |
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Mendels Law of Segregation |
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During the formation of gametes, paired units segregate randomly, so that each sex cell receives one or the other with equal likelihood. |
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Mendel's Law of Independent Assortment |
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During gamete formation, segregating pairs of unit factors assort independently |
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