Ca channel blockers

Verapamil

Diltiazem

selectively inhibit L-type slow Ca channels

impair condunction through AV

prolong AV refractory

dysrythmia of enhanced automaticity

(ectopic atrial tachy)

slow vent response to Atach/fib/flutter

CONSTIPATION

neg inotropic effects

decrease BP

incr PRI

NOT WITH BB

Other/Misc drugs

Dig

Adenosine

Mg Sulfate

vagotonic effects

slows conduction through AV node

rapid Atrial/AV tachydysrythm

aka supravent dys!

stim adenosine receptors in Atria, SA and AV

enhances phase 3 repolarization

decr slope of phase 4

shortens APD

terminates SVT-> preventing retrograde

conduction and re-entry through AV node

AV nodal dysrythmias

Adenosine is NOT indicated in tx of

Tx uses of Adenosine

DOC AV nodal dys

terminate PSVT (WPW)

asystole d/t complete block AV node conduction

flushing

angina

dyspnea

bronchospasm

corrects deficiency in Mg that can

cause cardiace dysryth

correct drug induced torsades &

supravent dysr assoc w/ Mg deficiency