Term
|
Definition
available alone or w/ erythromycin for use in recurrent otitis media
oral sulfonamide |
|
|
Term
|
Definition
available w/ trimethroprim aka co-trimoxazole, TMP-SMZ
as synergistic effect
used for RUG (resp, urinary, GI) |
|
|
Term
|
Definition
opthalmic sulfonamide
used for ulcerative blepharitis, bacterial conjuntivitis |
|
|
Term
|
Definition
prevents sepsis from burns, silver released is toxic
caution: the sulfa can be absorbed if covering large area
a topical sulfonamide |
|
|
Term
|
Definition
for burns, limited use because inhibit carbonic anhydrase. this can lead to metabolic acidosis
topical sulfonamide |
|
|
Term
|
Definition
best FQ for G-
decreases clearance of thephylline, methadone, tizanidine
binds to CYP450
2nd generation FQ |
|
|
Term
|
Definition
UTI only
2nd generation FQ |
|
|
Term
|
Definition
oral is generic
2nd generation FQ |
|
|
Term
|
Definition
3rd generation FQ
opthalmic solution only |
|
|
Term
|
Definition
|
|
Term
|
Definition
avoid if there are conduction anomalies
increased risk of prolonging Q-T interval in elderly: torsades de pointes
3rd generation FQ |
|
|
Term
|
Definition
metabolized mainly in liver (caution if hepatic disease is present)
can prolong Q-T interval in healthy pts
3rd generation FQ |
|
|
Term
|
Definition
approved for bacterial conjuntivitis
4th generation FQ |
|
|
Term
|
Definition
aka benzylPCN
IM/IV
can enter CNS if meninges are inflammed |
|
|
Term
|
Definition
|
|
Term
|
Definition
suspension IM only
procaine is a local anesthetic
|
|
|
Term
|
Definition
controlled release
PCN G + procraine + benzathine |
|
|
Term
|
Definition
long acting
benzathine + PCN G |
|
|
Term
|
Definition
aka phenoxymethylPCN
oral form
food interferes with absorption |
|
|
Term
|
Definition
PCNase resistant PCN
oral |
|
|
Term
|
Definition
PCNase resistant PCN
parenteral |
|
|
Term
|
Definition
PCNase resistant PCN
parenteral |
|
|
Term
|
Definition
oral or IV
aminoPCNs- extended spectrum
w/ sulbactam (beta-lactamase inhibitor)
used for peritonitis cause by B. fragilis |
|
|
Term
|
Definition
tablets, oral suspension, pediatric drop
better oral absorption than ampicillin
longer t1/2 than ampicillin
available with clavulanate aka co-amoxiclav
used to finish treatment of peritonitis (can't use to start because too slow)
|
|
|
Term
Ticarcillin + clavulanate |
|
Definition
antipseudomonas PCN
parenteral |
|
|
Term
piperacillin + tazaobactam |
|
Definition
antipseudomonas PCN
parenteral |
|
|
Term
|
Definition
IV
1st generation cephalosporin |
|
|
Term
|
Definition
oral
1st generation cephalosporin
|
|
|
Term
|
Definition
oral
1st generation of cephalosporin |
|
|
Term
|
Definition
oral every 8h
associated with Sx of serum sickness
2nd generation cephalosporin |
|
|
Term
|
Definition
every 12 h
2nd generation cephalosporin |
|
|
Term
|
Definition
a cephamycin
IV/IM
active against B. fragilis
|
|
|
Term
|
Definition
IV/IM
methylthiotetrazole side-chain antagonizes vit K, which leads to hypoprothrombinemia
must supplement with vit K
2nd generation cephalosporin |
|
|
Term
|
Definition
IV/IM
can cause kernicterus
can use with young infants only as one dose for gonorrhea conjuntivitis
3rd generation cephalosporin
good against meningitis |
|
|
Term
|
Definition
IV/IM
will also treat bacteroides
parent and metabolite active |
|
|
Term
|
Definition
|
|