Term
|
Definition
| Vancomycin, Trimethoprim-Sulfamethoxazole, Clindamycin, Linezolid, Daptomycin, Tigecycline, Fifth gen Cephalosporins |
|
|
Term
|
Definition
| Ceftazidime, Cefepime, Aztreonam, Levofloxacin, Ciprofloxacin, Carbapenems except Ertapenem, Penicillins with anti-lactimases, Tobramycin>Gentamicin |
|
|
Term
| Vancomycin Resistant Enterococcus Antibiotics |
|
Definition
Ampicillin(Aminopenicillins)
Linezolid
Daptomycin
Tigecycline
Nitrofurantoin
(Tiger LAND) |
|
|
Term
|
Definition
Ampicillin for Listeria and GBS
Ceftriaxone for Nisseria, HiB and S. Pneumo
Vancomycin for MRSA
Steroids for inflammation |
|
|
Term
|
Definition
Slowly bactericidal
Inhibits cell wall synthesis |
|
|
Term
|
Definition
Gram positive: Mainly; (ex. Staph, Strep, Enterococcus, Bacillus)
Gram Negative:None
Anaerobic: None
MRSA: Y
VRE: N
Pseudo: N
Other: |
|
|
Term
| Alpha hemolytic types of Streptococcus |
|
Definition
Partial Hemolysis
Viridans, S. Pneumo, S. milleri, S. bovis |
|
|
Term
| Beta-hemolytic types of Streptococcus |
|
Definition
Complete hemolysis
GAS (pyogenes), GBS (agalactiae), GCS |
|
|
Term
| Gamma-hemolytic types of Streptococcus |
|
Definition
No hemolysis
Enterococcal |
|
|
Term
|
Definition
Gram positive: S. pneumo, Listeria, MRSA, GBS
Gram Negative:Nisseria, HiB
Other: |
|
|
Term
|
Definition
Gram positive: S. Pneumo, S. aureus
Gram Negative: HiB, Legionella, Moraxilla
Other: Mycoplasma, Chlamydophila |
|
|
Term
|
Definition
Gram positive:Broad; MRSA, VRE
Gram Negative:None
Anaerobic: None
MRSA:Y
VRE:Y
Pseudo:N
Other: avoid in pulmonary pneumonia |
|
|
Term
|
Definition
Bactericidal
Disrupts cell membrane |
|
|
Term
|
Definition
|
|
Term
| Fluoroquinolones Mechanism |
|
Definition
Bactericidal
Inhibits DNA gyrase |
|
|
Term
| Dosing of problems with fluoroquinolones |
|
Definition
| Avoid aluminum, calcium, iron magnesium |
|
|
Term
| Fluoroquinolones general spectrum |
|
Definition
Gram positive:Varying
Gram Negative:Varying
Anaerobic:Some varying
Other:
MRSA:N
VRE:N
Pseudo:Some |
|
|
Term
|
Definition
Gram positive:Less
Gram Negative:Good
Anaerobic:Less
Other:
MRSA:N
VRE:N
Pseudo:Y |
|
|
Term
|
Definition
Gram positive:Good (S. Pneumo)
Gram Negative:Ok
Anaerobic:Some
Other:Does not get into urine
MRSA:N
VRE:N
Pseudo:N |
|
|
Term
|
Definition
Gram positive:Good(S. pneumo)
Gram Negative: good (Pseudo)
Anaerobic: Weak
Other:
MRSA: N
VRE: N
Pseudo: Y |
|
|
Term
| Fluoroquinolones side effects |
|
Definition
QT prolongation
Tendinopathy |
|
|
Term
| Trimethoprim-Sulfamethoxazole Mechanism |
|
Definition
Bacteriostatic
Inhibit folate synthesis |
|
|
Term
| Trimethoprim-Sulfamethoxazole Dosing |
|
Definition
SS 80/400, DS 160/800
Soft tissue infections: 10mg/kg TMP
PCP: 15-20mg/kg TMP
Menigitis: 20mg/kg TMP |
|
|
Term
| Trimethoprim-Sulfamethoxazole spectrum |
|
Definition
Gram positive: S. aureus, Nocardia, NOT strep
Gram Negative:Rods
Anaerobic:N
Other:PCP, Toxo
MRSA:Y
VRE:N
Pseudo:Y |
|
|
Term
|
Definition
Bactericidal
Produces free radicals |
|
|
Term
|
Definition
Gram positive:Ok (Clostridium)
Gram Negative: Ok
Anaerobic: Great
Other: Protozoa
MRSA:N
VRE:N
Pseudo:N |
|
|
Term
|
Definition
Bactericidal
Attacks cell membranes |
|
|
Term
|
Definition
Gram positive:Not really
Gram Negative:Good (Klebsiella, Acinetobacter)
Anaerobic: Not really
Other:
MRSA:N
VRE:N
Pseudo:Y |
|
|
Term
|
Definition
Nephrotoxicity
Neurotoxicity |
|
|
Term
| Natural Penicillin Spectrum |
|
Definition
Gram positive:
Gram Negative:
Anaerobic:
Other: Mainly Syphilis, GAS, Actinomyces
MRSA:
VRE:
Pseudo: |
|
|
Term
| Penicillinase resistant Penicillins |
|
Definition
| Nafcillin, Oxacillin, Methicillin |
|
|
Term
| Penicillinase Resistant Penicillins' Spectrum |
|
Definition
Gram positive:Yes, (MSSA,listeria no MRSA)
Gram Negative:Good
Anaerobic:N
Other:
MRSA:N
VRE:N
Pseudo:N |
|
|
Term
|
Definition
|
|
Term
| Aminopenicillins Spectrum |
|
Definition
Gram positive:Good (listeria)
Gram Negative:Some (HiB)
Anaerobic:N
Other:
MRSA:N
VRE:Y
Pseudo:N |
|
|
Term
|
Definition
Amoxicillin or Ticarcillin with Clavulanic acid
Piperacillin with Tazobactam
Ampicillin with sulbactam |
|
|
Term
| Penicillins plus spectrum |
|
Definition
Gram positive:Good (good for mixed oral or GI)
Gram Negative:Some
Anaerobic: Good
Other:Not SPACE (Serratia, Pseudo, Acineto, Citro, Entero)
MRSA:N
VRE:N
Pseudo:N |
|
|
Term
| First generation cephalosporins |
|
Definition
|
|
Term
| First generation cephalosporin spectrum |
|
Definition
Gram positive:Good
Gram Negative:weak
Anaerobic:N
Other: good for surgical prophylaxis
MRSA:N
VRE:N
Pseudo:N |
|
|
Term
| Second Generation Cephalosporins |
|
Definition
| Cefuroxime, Cefoxitin, Cefotetan |
|
|
Term
| Second Generation Cephalosporins spectrum |
|
Definition
Gram positive:Good
Gram Negative:Some
Anaerobic:N
Other:
MRSA:N
VRE:N
Pseudo:N |
|
|
Term
| Third Generation Cephalosporins |
|
Definition
| Ceftriaxone, Ceftazidime, etc. |
|
|
Term
| Third Generation Cephalosporins' spectrum |
|
Definition
Gram positive:Less (S. pneumo)
Gram Negative:More (H. Inf)
Anaerobic:N
Other:
MRSA:N
VRE:N
Pseudo: Ceftazidime |
|
|
Term
| Fourth Generation Cephalosporins |
|
Definition
|
|
Term
|
Definition
Gram positive:Good
Gram Negative:Good
Anaerobic:Limited
Other:
MRSA:N
VRE:N
Pseudo:Y |
|
|
Term
| Fifth Generation Cephalosporins |
|
Definition
| Ceftaroline, Ceftobiprole |
|
|
Term
| Fifth Generation Cephalosporins Spectrums |
|
Definition
Gram positive:Good (S. pneumo)
Gram Negative:Good (Klebsiella)
Anaerobic:
Other:
MRSA:Y
VRE:N
Pseudo:N |
|
|
Term
|
Definition
| Imipenem, Meropenem, Ertapenem, Doripenem |
|
|
Term
|
Definition
Gram positive:Good (except MRSA & entero)
Gram Negative:Good including ESBL
Anaerobic: Good
Other:
MRSA:N
VRE:N
Pseudo:Y (not Ertapenem) |
|
|
Term
|
Definition
|
|
Term
|
Definition
Gram positive:N
Gram Negative:Good
Anaerobic:N
Other:
MRSA:N
VRE:N
Pseudo:Y |
|
|
Term
|
Definition
| Isoniazide, Rifampin, Pyrazinamide, Ethambutol |
|
|
Term
|
Definition
| Erythromycin (gernerally only used for diabetic gastroparesis), Azithromycin, Clarithromycin |
|
|
Term
|
Definition
Bacteriostatic
Inhibits 50S subunit |
|
|
Term
|
Definition
Gram positive:S. pneumo and Beta-strep, NOT Staph
Gram Negative:H. inf, Moraxella
Anaerobic: N
MRSA:N
VRE:N
Pseudo:N
Other: Legionella, Mycoplasma, Chlamydia, H. pylori, MAC |
|
|
Term
|
Definition
|
|
Term
|
Definition
Bacteriostatic
Inhibits 50S subunit |
|
|
Term
|
Definition
Gram positive:MRSA(Community and D-test neg), TSS, mouth org, osteo
Gram Negative:N
Anaerobic: N
MRSA:Y(Community and D-test neg)
VRE:N
Pseudo:N
Other: Attains high concentrations in abscesses |
|
|
Term
|
Definition
Bacteriostatic
Inhibits 50S subunit |
|
|
Term
|
Definition
Gram positive:Cocci only
Gram Negative:N
Anaerobic: Some
MRSA:Y
VRE:Y
Pseudo:N
Other: |
|
|
Term
|
Definition
Case reports of serotonin syndrome
Bone marrow suppression
Long term use: Peripheral neuropathy and Ocular toxicity |
|
|
Term
|
Definition
| Tetracycline, Minocycline, Doxycycline |
|
|
Term
|
Definition
Bacteriostatic
Inhibits 30S subunit |
|
|
Term
|
Definition
Gram positive:S. aureus, coag neg staph
Gram Negative:N
Anaerobic: N
MRSA:N
VRE:N
Pseudo:N
Other: Mycoplasma, C. psittaci, Chlamydia, Lyme, Rickettsiae, Acne, Syphilis |
|
|
Term
| Tetracycline dosing considerations |
|
Definition
Don't give with Ca, Mg, Fe, Al
Tetracycline has highest urine levels |
|
|
Term
|
Definition
Teeth discoloration in children and preg
Photosensitivity
Pill esophagitis
Reversible vertigo (esp Mino) |
|
|
Term
|
Definition
| Bacteriostatic Inhibits 30S subunit |
|
|
Term
|
Definition
Gram positive:Very broad
Gram Negative:Good
Anaerobic: Good
MRSA:Y
VRE:Y
Pseudo:N
Other: No 3P's, (Pseudo, Proteus, Providencia), Does not get high blood levels or urine levels, best for soft tissue infections |
|
|
Term
|
Definition
| Gentamicin, Tobramycin, Amikacin, Streptomycin |
|
|
Term
|
Definition
Bactericidal
Inhibit 30S subunit |
|
|
Term
|
Definition
Gram positive:None except in synergy with Beta-lactams for E. Fec
Gram Negative:Esp rods
Anaerobic: None at all
MRSA:N
VRE:N
Pseudo:Tobra>Genta
Other: |
|
|
Term
|
Definition
| Nephrotoxicity, Ototoxicity, Rare neuromuscular paralysis |
|
|
