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Antigen Recognition by and Activation of Cytotoxic T Cells
process
7
Anatomy
Undergraduate 1
10/31/2012

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Term
start
Definition
Antigen Recognition
Term
Antigen Recognition

how does this occur?
Definition
when a CD8 T cell encounters an appropriate antigen on the surface of another cell that is bound to a Class I MHC protein.
Term
after Antigen Recognition is
Definition
Costimulation
Term
Costimulation describe
Definition
T cell must be chemically or physically stimulated by the abnormal target cell before it can be activated
Term
after Costimulation is
Definition
Activation and Cell Division
Term
Activation and Cell Division result in
Definition
T cell activation and cell division, producing active TC cells and memory TC cells
Term
last step
Definition
Destruction of Target Cells by
Perforin release:
Destruction of plasma membrane

Stimulation of apoptosis:
Disruption of cell metabolism

Cytokine release:
Lymphotoxin release
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