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barry 2013
patho 1 test 2 (coagulation factors)
13
Other
Graduate
03/24/2011

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Term
Factor I
Definition
Fibrinogen
common pathway
converted to fibrin, which is the web-like substance of clot
Term
Factor II
Definition
Prothrombin
common pathway
converted to thrombin, which enzymatically converts fibrinogen to fibrin
Term
Factor III
Definition
Tissue factor or tissue thromboplastin
activates Extrinsic pathway
Term
Factor IV
Definition
Calcium ions
needed for almost all stages of coagulation process
Term
Factor V
Definition
Proaccelerin, labile factor, or platelet accelerator
Both extrinsic and intrinsic
Term
Factor VI
Definition
no other name; now thought to be same substance as factor V
Term
Factor VII
Definition
Serum prothrombin conversion accelerator (SPCA) or stable factor
Both extrinsic and intrinsic
Term
Factor VIII
Definition
Antihemophilic factor (AHF)
Intrinsic pathway
Term
Factor IX
Definition
Plasma thromboplastin component OR Christmas factor
Intrinsic Pathway
Term
Factor X
Definition
Stuart factor OR thrombokinase
Both extrinsic and intrinsic pathways
Term
Factor XI
Definition
plasma thromboplastin antecedent (PTA)
Intrinsic pathway
Term
Factor XII
Definition
Hageman factor OR glass factor
Intrinsic pathway
activates plasmin
Term
Factor XIII
Definition
Fibrin stabilizing factor
Cross-links fibrin and renders it insoluble
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