Shared Flashcard Set

Details

Bb- preparation and use of blood and blood component
test 1
40
Health Care
Undergraduate 4
06/14/2009

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Cards

Term
What percent of transfused red cells should be viable 24 hours post transfusion?
Definition
75%
Term
What temperature are RBC's stored at?
Definition
1-6 C
Term
What is the maximum temperature for transporting RBC's?
Definition
10 C
Term
What temperature are platelets and granulocytes stored?
Definition
20-24 C
Term
What happens to the pH of stored blood over time?
Definition
It decreases/acidifies
Term
What happens to the 2,3-DPG of stored red cells over time?
Definition
It decreases. It returns to normal within 24 hours after being transfused.
Term
What happens to the amount of ATP in stored blood over time?
Definition
It decreases.
Term
What happens to plasma potassium levels of stored blood over time?
Definition
It increases because potassium leaks out of cells.
Term
What happens to plasma hemoglobin in stored blood over time?
Definition
it increases as cells lyse
Term
What is a cellular metabolite that increases over time in stored blood?
Definition
plasma NH3
Term
After collecting the whole blood, the first centrifugation is done, separating the blood into what two components?
Definition
platelet rich plasma and RBC's.
Term
The second centrifugation separates what two components?
Definition
platelets and plasma.
Term
What do you do after separating the platelets from the plasma?
Definition
Let the platelets rest for an hour, then rotate them slowly.
Term
If something happens to the bag and it becomes an open system, how long can you keep a product stored at 1-6 C?
Definition
24 hours.
Term
If something happens to the bag and it becomes an open system, how long can you keep a product stored at 20-24 C?
Definition
4 hours.
Term
How long can you keep platelets after pooling them?
Definition
4 hours.
Term
What is the minimum dose of radiation targeted to the center portion of the container when irradiating blood components? WHat is the minimum dose for other parts?
Definition
25 Gy to the center, 15 Gy to other parts.
Term
What is the purpose of irradiating blood components?
Definition
to prevent graft vs host reaction.
Term
Irradiation prevents proliferation of what cells?
Definition
T-lymphocytes.
Term
What two situations call for irradiation of blood products?
Definition
immunodeficient patient or recipients of blood from any blood relative
Term
When transporting red cells, what do you use to keep them between 1-10 C?
Definition
wet ice.
Term
How long does it take, at room temperature, for rbc's to warm up to 10 C?
Definition
about 30 minutes.
Term
When transporting fresh frozen plasma, what temperature does it have to be kept at?
Definition
at or below -18 C. Dry ice is usually used.
Term
What is the shelf life of whole blood using CPD?
Definition
21 days.
Term
What is the shelf life of whole blood using CPDA-1?
Definition
35 days
Term
How long can you keep irradiated whole blood?
Definition
original outdate or 28 days from date of irradiation, whichever is sooner.
Term
What is the maximum hematocrit of packed red cells?
Definition
80 %
Term
How long can you keep frozen deglycerolized red blood cells?
Definition
10 years.
Term
how long can you keep washed red blood cells?
Definition
24 hours at 1-6 C after washing.
Term
How long can you keep granulocytes from granulocyte pheresis?
Definition
24 hours after collection; best if used in 6 hours.
Term
After collecting the blood donation, how long do you have to separate platelets from whole blood?
Definition
platelets must be separated from whole blood within 8 hours.
Term
How long can you keep platelet pheresis from a single donor?
Definition
5 days.
Term
How long can you keep fresh frozen plasma after thawing?
Definition
24 hours at 1-6 C
Term
How long can you keep FFP if frozen at -18C?
Definition
12 months.
Term
How long can you keep FFP if frozen at -65C?
Definition
7 years.
Term
How long can you keep frozen cryoprecipitate?
Definition
12 months.
Term
How long can you keep cryoprecipitate after thawing?
Definition
6 hours.
Term
What temperature is cryoprecipitate frozen at?
Definition
-18 C
Term
What temperature is thawed cryoprecipitate stored at?
Definition
20-24C
Term
How long can you keep cryoprecipitate after pooling?
Definition
4 hours.
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