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BIO 111
Module 6
50
Biology
Undergraduate 1
07/21/2012

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Term
a genomic library is:
Definition
a collection of cloned DNA pieces from an organism's genome
Term
the process of making multiple copies of a gene by inserting it into a host genome and culturing the host is called
Definition
gene cloning
Term
a gene that can cause cancer when present in a single copy in a cell is called a(n)
Definition
oncogene
Term
the use of organisms to develop useful produce is called:
Definition
biotechnology
Term
a________is required to transfer genes from one organism to another
Definition
vector
Term
which DNA sequence below would be a palindrome sequence
Definition
AGCGCT
Term
a chromosome library is a collection of all of the DNA:
Definition
contained in one chromosome
Term
to avoid the introduction of introns into the vector, a _____copy of mature mRNA is made, using the enzyme_____
Definition
cDNA; reverse transcriptase
Term
the area of genomics that is concerned with mapping and sequencing genomes is called________genomics
Definition
stuctural
Term
the FBI currently determined an individual's DNA profile using;
Definition
13 STR markers
Term
an organism in which foreign genes have been incorporated is called a
Definition
transgenic organism
Term
which technique rapidly replicates specific DNA fragments in vitro
Definition
polymerase chain reaction
Term
a probe is which of the following
Definition
a piece of radioactively labeled DNA that is used to find a specific gene
Term
in the southern blot technique_____is/are transferred from a gel to a nitrocellulose or nylon membrane
Definition
DNA
Term
which sex chromosomes number abnormally occurs when there is a nondisjunction of the two X chromosomes of the egg? (The individual has sex chromosomes XXY)
Definition
klinefelter syndrom
Term
if a chromosome fragment breaks off and then reattaches to the original chromosome but in the reverse direction, the resulting chromosomal abnormality is called a(n)
Definition
inversion
Term
karyotyping is useful for determining
Definition
the number of chromosomes in an individual
Term
the normal human karyotype contains______chromosomes
Definition
46
Term
autosomal aneuploidies arise by:
Definition
nondisjunction
Term
turner syndrome is an example of a _______ condition
Definition
monosomic
Term
persons having an XO karyotype are sterile females. they have______syndrome
Definition
turner
Term
down syndrome is an example of a _____ condition
Definition
trisomic
Term
cutting DNA with a particular restriction enzyme produces_____that can be separted by gel electrophoresis
Definition
restriction fragments
Term
an advantage of chorionic villus sampling (compared with amniocentesis) is that:
Definition
chorionic villus sampling can be performed much earlier than can amniocentesis
Term
genetic screening can be used to identify all of the following except
Definition
none of these; all can be identified using genetic screening techniques
Term
polyploidy is:
Definition
the presence of multiple sets of chromosomes
Term
translocation occurs when:
Definition
part of a chromosome breaks off and attaches to a nonhomologous chromosome
Term
gene therapy is:
Definition
replacing a mutant allele in certain body cells with a normal allele
Term
preimplantation genetic diagnosis is done
Definition
after in vitro fertilization on cells from the embryo
Term
cells become progressively committed to specific patterns of gene activity and developmental fate through a process known as
Definition
determination
Term
cells becoming progressively more specialized in their structure and gene activity is known as
Definition
differentiation
Term
the concept of nuclear equivalence states that
Definition
all of the somatic cells in an adult organism have the same genes
Term
differential gene expression is defined as
Definition
regulation during development that varies the type and quantity of gene products among cells
Term
DNA ligase binds
Definition
nucleotides together
Term
the significance of totipotency is that
Definition
genes are not regularly lost during development
Term
totipotent nuclei are capable of
Definition
directing normal development of an organism
Term
undifferentiated cells that can divide and specialize to form a variety of different cells are called
Definition
stem cells
Term
cells able to divide and form some types of cells in an organism are called
Definition
pleuripotent stem cells
Term
totipotent human stem cells can apparently be obtained only from
Definition
zygotes
Term
in the process known as______, the fate of a cell is influenced by interactions with neighboring cells
Definition
induction
Term
instances in which cells die shortly after they are produced in development is called
Definition
apoptosis
Term
proto-oncogenes can be converted to oncogenes by
Definition
mutation
Term
genes that normally block cell division are called
Definition
tumor suppressor genes
Term
proto-oncogenes code for
Definition
growth factor receptors and other components of the growth control cascade
Term
gel electrophoresis sorts DNA molecules on the basis of their
Definition
size
Term
in______, a genetic mutation codes for an abnormal hemoglobin molecule that is less soluble than usual and more likely than normal to deform the shape of the red blood cell
Definition
sickle cell anemia
Term
if you commit a crime, you need to make sure that you do not leeave even the smallest speck of blood, hair, etc. from your body behind because if you do, the DNA in this material can be amplified by_______, subjected to genetic analysis, and used to identify you as the perpetrator of the crime
Definition
PCR
Term
in recombinant DNA experiments, _____is used to cut pieces of DNA, and _____ joins these segments to form recombinant DNA
Definition
restriction enzyme...DNA ligase
Term
restriction enzymes
Definition
cut DNA at specific sites
Term
the enzyme that adds nucleotides to a new strand of DNA, using the old strand as a pattern is called
Definition
DNA polymerase
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