Term
DNA polymerase III can _______ |
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Term
nucleotide excision repair |
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Definition
(1) enzymes detect an irregularity and cut damaged strand (2) enzyme excises nucleotides on damaged strand (e) DNA polymerase fills in gaps in 5-3 direction (4) DNA ligase links it together |
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Definition
• binds at replication fork • breaks H-bonds between bases and opens double helix |
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Definition
• binds ahead of the replication fork • breaks covalent bonds in DNA backbone to relive twisting forces cause by opening the helix |
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Term
single-strand binding protein |
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Definition
• binds after replication fork • prevents H-bonds between bases and stabilize single-stranded DNA |
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Definition
only one primer needed polymerase moves toward replication fork made continuously |
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Definition
polymerase moves away from replication fork made in segments multiple primers needed |
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both leading and lagging strand |
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Definition
synthesized in 5-3 direction |
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Definition
catalyzes synthesis of RNA primer |
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Term
DNA polymerase III's role in DNA synthesis |
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Definition
holds DNA polymerase in place during strand extension |
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Definition
removes RNA primer and replaces it with DNA |
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Definition
catalyzes joining of Okazaki fragments into a continuous strand |
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