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| substrate for the TCA cycle, generated by the pathways for oxidation of fatty acids, amino acids, acetate and ketone bodies. |
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| a-ketoglutarate dehydrogenase - |
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| another name for the TCA cycle, based on the first compounds found to participate (citrate). |
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| isocitrate dehydrogenase - |
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| enzyme that catalyzes the oxidation of the alcohol group and subsequent cleavage of carboxyl group to release CO2, forming a-ketoglutarate. releases the first CO2 in the cycle. |
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| another name for the TCA cycle. |
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| coenzyme found in a-keto acid dehydrogenase complexes. it is synthesized from carbohydrate and amino acids but does not need a vitamin origin. lipoate is attached to the transacylase enzyme by its carboxyl group, that is bound covalently to terminal -NH2 of lysine in protein. |
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| neurotransmitter synthesis - |
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| pyruvate dehydrogenase complex - |
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| catalyzes the reaction that oxidizes pyruvate to acetyl CoA, this makes for an important connection of the glycolsis and the TCA cycle pathway. |
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| pyruvate dehydrogenase kinase - |
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| succinate dehydrogenase - |
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| succinyl CoA synthetase - |
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| succinate dehydrogenase - |
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| contains covalently bound FAD, resides in the inner mitochondrial membrane to transfer electrons directly to the ETC. |
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| tricarboxylic acid cycle occurring in the mitochondrial matrix and once phase in the inner membrane. this cycle of metabolism is designed to conserve energy from the oxidation of the 2 carbon acetyl group of acetyl CoA that is oxidized by 2 CO2 molecules. if efficiently stored energy by transferring electrons from the intermediates of the cycle to NAD+ and FAD. this cycle requires a large number of vitamins and minerals to function, including: niacin (NAD+), riboflavin (FAD and FMN), panthothenic acid (CoA), thiamine, Mg2+, Ca2+, Fe2+, and phosphate. Very efficient cycle in converting energy from chemical bonds of acetyl groups to other forms. |
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