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-G1 Cell growth and activity -cells spend most time in interphase -Synthesis- chromosomes replicate G2- cell prepares to divide |
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Holds two sister chromatids together |
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maternal and paternal copies of same chromosome |
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identical copies of a chromosome |
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"wed" of microtunules -pull chromosomes apart |
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microtubules- organizing center; organizes the spindle |
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Produces cells that are exactly the same prophase metaphase anaphase telophase |
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-chromatin condenses -spindle forms -nuclear membrane disappears |
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choromosomes line up in central region of the cell (spindle equator) |
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sister chromatids split and move toward opposite poles |
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chromosomes become diffuse -daughter nuclei form -nuclear membrane reappears |
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physical division of the cell formation of -cleavage furrow-animals -cell plate- plants |
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-all organisms are made up of one or more cells -cells are the basic unit of life and the smallest unit of life -every new cell comes from a pre-existing cell |
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maintains the cell as a distinct entity |
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consists of semi-fluid material and organelles |
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tiny compartments within a cell that have specific functions |
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hereditary info -found within distinct nucleus (eukaryote) -no distinct nucleus (prokaryote) |
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store information -like: dna catalyze reactions like proteins |
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hydrophilic heads- outside hydrophobic tails- inside -proteins and other lipids are embedded within the membrane |
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Plasma membrane functions |
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-separates internal and external enviroment -controls movement of meterials in and out of cell -allos cell to interact with other cells |
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found in prokaryotes and eukaryotes -structure: composed of RNA and proteins -function: assemble amino acids into proteins |
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bacteria and Archaea -have no distinct nucleus (DNA is in the cytoplasm) -contain few organelles other than ribosomes -cell wall |
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-nucleus -endomembrane system -mitochondria -chloroplasts (plants only) -cytoskeleton |
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nuclear envelope houses DNA --chromatin: DNA and proteins -where RNA is made |
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-endoplasmic recticulumn (ER) -gogli complex -various vesicles --organelles involved in the synthesis, storage, and transportation of important molecules |
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-within the endomembrane system Network of membranes -rough ER: has ribosomes (where protein synthesis occurs) -smooth ER: site of lipid synthesis (phospholipids and cholesterol) and transport |
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-recieve macromolecules from the ER -assemble, modify, and package macromolecules for exporting from the cell |
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-transport, storage, and recycling --lysosomes (animals): house enzymes that digest macromolecules (like carbs and proteins) --vacoules (plants): store water |
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-sites of cellular respiration: production of energy (ATP) using sugar from foods -have their own DNA |
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-only in plants -sites of phtosynthesis -have their own DNA |
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-microfilaments- actin -intermediate filaments- fibrous proteins -microtubules- tubulins |
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movement- cilia and flagella internal shape and structure- anchor organelles and serve as tracks for organelles movement -cell division |
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found in plants, fungi, and algae -cellulose (plants) -silica (diatoms) outside plasma membrane |
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a trait becomes more common in a population over time (evolution) |
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trait that gives the individual an advantage in survival or reproduction, under a given set of circumstances |
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the production of haploid gametes |
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-Interphase (DNA is replicated) -Mitosis -cytokinesis -produces 2 genetically identical cells |
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-chromatin condenses -spindle forms -nuclear membran disappears -***homologous pair up- form tetrads |
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homologous line up at equator as tetrads |
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homologues split and move toward opposite poles -sister chromatids remain together |
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Telophase and Cytokinesis (Meiosis) |
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spindle disappears -daughter nuclei form |
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Meiosis I Vs. Meiosis II!!!!!! |
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Meiosis I: -homologous chromosomes are seperated -sister chromatids are still attached to one another Meiosis II: seperation of the sister chromatids |
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Mitosis: -growth and maintenance of size -asexual reproduction
Meiosis -production of haploid gametes for sexual reproduction |
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Advantage of sexual VS. asexual reproduction |
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-genetic variation --combination of alleles -material for natural selection |
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Process of generating genetic variation |
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-crossing over -random assortment of chromosomes into gametes -fertilization |
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Occurs only in Prophase I of meiosis!! -homologues exchange genetic info -produce gene combinations different from those of original chromosomes |
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-occurs during metaphase I -pairs of homologous chromosomes line up randomly -results in different possible combinations or chromosomes in gametes |
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Mendel's Theory of Independent Assortment |
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-Different traits assort independently of one another -Explanation: random assortment of homologous chromosomes during meiosis |
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medical conditions caused by inherited alleles |
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Autosomal Dominant Disorders |
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a condition arising from a dominant allele on an autosome |
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Autosomal Dominant Disorders |
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Huntingtons -symptoms show at 35-40 -gradual degeneration of nervous system and personality disorders -100% fatal :( |
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Autosomal Recessive Disorders |
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a condition arising from a recessive allele on an autosome |
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Autosomal Recessive disorders |
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Albinism PKU- defective enzyme- cant break down phenylalanine -build up of excess phentlalanine in blood and brain cells -causes damage to the nervous system and mental impairment |
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comes from Autosomal Recessive Disorders -gene located on chromosome 21 -easy to detect at birth by blood test -treatment: restrict dietary intake to phenylalanine |
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X-linkes recessive disorder |
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a condition arising from a recessive allele on an X chromosome |
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How can we test for genetic problems |
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-genetic screening -genetic counseling -prenatal diagnosis -preimplantation diagnosis |
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Mendel's Theory of Segregation |
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Gametes only get one copy of each gene |
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Mendel's Theory of Independent Assortment |
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Different pairs of alleles assort independently of one another -Result: Huge gamete diversity |
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One allele is not fully dominant over its partner |
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two alleles share dominance |
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when one gene affects more than one trait |
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When one gene overrides the effect of a separate gene ex- coat color in labradors |
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a trait influenced by multiple genes -continuous variation ex- height and eye color (remember poly=many?) |
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influence of the environment on the expressive of a genotype ex-goat color of himalayan rabbits -how their coat grows dark on feet, ears and face to keep those coldest parts warm |
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