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Biosystems
The Integumentary System
23
Anatomy
Undergraduate 1
09/05/2011

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Term
integumentary system made up of
Definition
skin, glands, hair, nails
Term
skin functions
Definition
-protection
-body temp regulation
-collect sensory info
Term
skin 3 regions
Definition
-epidermis
-dermis (majority)
-hypodermis
Term
hypodermis
Definition
-not technically part of skin
-mostly adipose tissue
Term
epidermis
Definition
-stratified squamous with keratin
-AVASCULAR
-keratinocytes
-melanocytes
-epidermal dendritic (Langerhans) cells
-tactile (Merkel) cells
Term
keratinocytes
Definition
produce fibrous keratin protein
Term
melanocytes
Definition
-10-25% of cells in lower epidermis
-produce pigment melanin
Term
epidermal dendritic (Langerhans) cells
Definition
macrophages that help activate immune system
Term
tactile (Merkel) cells
Definition
touch receptors
Term
layers of epidermis
Definition
-stratum corneum
-stratum lucidum
-stratum granulosum
-stratum spinosum
-stratum basale
Term
stratum basale (germinativum)
Definition
-single row of stem cells
-25-45 days to reach top
Term
stratum spinosum (prickly layer)
Definition
-layers of keratinocytes (prickly) attached to desmosomes
-abundant melanin and dendritic cells
Term
stratum granulosum (granular layer)
Definition
-3-5 layers of keratinocytes
-cells flatten and begin to disintegrate
-last layer to receive nutrients
Term
stratum lucidum
Definition
-in thick skin
-flat dead keratinocytes
Term
stratum corneum (horny layers)
Definition
-20-30 rows of dead keratinocytes
-majority
-protects, waterproofs
Term
how topical meds act
Definition
-lipid soluble
-chem disruption
-mechanical disruption (radiation)
Term
dermis
Definition
-strong, flexible CT
-papillary
-reticular
Term
papillary layer of dermis
Definition
-smaller
-areolar CT
-vascular
-capillary loops
-Meissner's corpuscles (touch)
-free nerve endings
Term
reticular layer of dermis
Definition
-80% of dermis
-all 3 fibers
-more fibrous
Term
hypodermis
Definition
-protective layer
-primary anchor
-stores fat
Term
excessive sun exposure
Definition
-damages DNA
-bundles elastin
-suppresses immune system
-breaks down folic acid (DNA repair, RBC production)
Term
sweat glands and sebaceous glands are
Definition
epithelial tissue
Term
hair, hair follicles, nails are
Definition
keratin
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