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Block 2 Path lab Pulmonary
asdf
66
Medical
Graduate
12/07/2009

Additional Medical Flashcards

 


 

Cards

Term

65 y.o SOB goes away, several months later SOB, localized chest pain on right side.

 

pleural friction rub + thrombosis on right posterior tibial vein

Definition

Infarct

periphery

subpleural

wedge-shaped

well-demarcated.

 

fibrinous pleuritis: friction rub

 

embolism support.

 

 

Term
5 risk factors for thrombosis and PE
Definition

chronic immobilization

 

injury

 

previous episode

 

malignancy

 

Factor 5, protein C/S defect.

Term

9 mo difficulty breathing, fever

 

patchy bilateral infiltrate

 

Diffuse alveolar damage

 

bronchitis/bronchiolitis

 

multinucleated giant cell with intracytoplasmic inclusion

Definition
RSV until proven otherwise
Term

DDx:

 

multinucleated giant cell with nuclear inclusions

 

vs.

 

intracytoplasmic inclusions

Definition

nuclear:

HSV

VZ

 

intracytoplasmic:

RSV

parainfluenza

measles

Term

interstitial dz

 

adenocarcinoma

mesothelioma

 

hypoxemia inducecd pulm. HTN induced RHF

 

see asbestos body on surface Fe and protein

Definition
asbestosis
Term

bird, progresive SOB disappear only when bird removed

granulomas.

 

vs.

 

6 y.o. wheezes when see a cat

eosinophil infiltration

Definition

hypersensitivity pneumonia

 

vs. asthma

Term

33y.o. binge drinker, 3cm cavity mass with foul-smelling sputum

 

colony of actinomyces

 

dx:

 

from what

Definition

lung abscess

 

aspiration b/c actinomyces are common mouth organism

Term
5 ddx for cavity mass
Definition

TB

 

histo, other fungal

 

wegener's

 

abscess

 

SCC

Term

43 y.o. HIV apical infiltrate in both lung, pleural effusion

PPD negative.

necrotizing granuloma

 

vs.

 

midzone of lung

Definition

2ndary TB

PPD false negative in HIV

 

vs.

 

1ary TB

Term

ddx for necrotizing granuloma

 

vs.

 

non-necrotizing granuloma

Definition

histo

TB

crypto

 

vs.

 

sarcoidosis

Term

52 y.o. lung transplant, fever, patchy bilateral lung infiltrate

 

intranuclear + intracytoplasmic inclusion

Definition
CMV
Term

80 y.o. CHF with basilar and pleural effusion.

pleural fluid protein 2.0 g/dL

LD is 100IU

Definition

pulmonary edema

 

transudate

Term

emphysema

 

apical

 

middle

Definition

centriacinar

 

panacinar

Term

34 y.o. asymptomatic , enlarged mediastinal and hilar LN

 

giant cell w/o necrotizing centers

Definition
sarcoidosis
Term

several pneumonia over last 2 y.o.

well circumscribed 2 cm nodule in RUL at endobronchial nodule

diarrhea and flushing over last several  month

 

uniform cell with islands of neurosecretory granuules

 

dx:

 

what stain would u order

 

why diarrhea and flushing

Definition

carcinoid:

 

chromogranin A & synaptophysin

 

carcinoid syndrome: neuroendocrine cell

Term

carcinoid

 

carcinoma?

 

benign?

 

prognosis?

 

what runs a more aggresive course

Definition

not bronchogenic carcinoma

 

malignant

 

good prog

 

atypical carcinoid

Term
cough, fever, LLL infiltrate of PMN
Definition
acute pneumonia
Term

50 y.o. chest discomfort, peripheral infiltrate.

 

see proliferation in cytoplasm of macrophage

Definition
histo
Term
where does lymphatics course thru
Definition
interlobular septum
Term
hemosiderin-layden macrophage and edema fluid occupying alveoli
Definition
chronic passive congestion
Term
wedge shaped redness at subpleural
Definition
pulm. infarct
Term
IV drug abuser with polarizable substance present adjacent to blood vessel from
Definition
talcosis
Term
small artery dem. medial hypertrophy and aggregate of small capillary.
Definition
pulmonary HTN and plexiform lesion
Term
DAD and yaline membrane line alveolar septa
Definition
acute stage ARDS
Term
tan yellow spots center around airway and neutrophils fill bronchiole adn adjacent alveoli.
Definition
acute bronchcopneumonia from exudate
Term
suppurative exudate cover pleural surface form pleural rind and pleural adhesion imparing lung expansion
Definition
empyema
Term
aspirated oily substance phagocytied by mac on foamy appearance. fat trigger fibrosis.
Definition
exogenous lipoid pneumonia
Term
bronchial obstuction by tumor, aspirated oily substance phagocytized by macrophage appear foamy appearance, but no large fat collection
Definition
endogenous lipoid pneumonia
Term
suppurative necrosis of lung by bacterial infection appear consolidated at RLL.
Definition
aspiration caused abscess
Term
DAD, septa widened, prominent fibroblast proliferation, multinucleated giant cell with intracytoplasmic inclusion
Definition
RSV
Term
lungs red and firm, necrosis of bronchial epi, DAD
Definition
influenza A
Term
ronchiole and alveoli filled with acute inflammatory exudate, alveolar septa cannot be identified around bronchiole, basophilic intranuclear inclusion obscuring nuclear envelope
Definition
adenovirus induced necrotizing pneumonia. smudge cell
Term
multinucleated giant cell has intranuclear inclusion and ground glass nuclei. bronchial epi is ulcerated.
Definition
HSV-induced ulcerative tracheobronchitis.
Term
pulmonary mac has intranuclear inclusion and intracytoplasmic inclusion
Definition
CMV pneumonia
Term
alveoli has eosinophilic exudate with honeycomb appearance open spacec occupied by round cysts with central dot. with silver methenamine stain.
Definition
PCP
Term
apex of lung with pleural plaque with zone of consolidation
Definition
postprimary TB
Term
the infected pleural space marked by expanded and filled with white material representing caseating granuloma.
Definition
TB empyema
Term
multiple necrotizing granuloma with small yeaste under silver methenamine and narrow single budding. see clusters inside dead macrophage
Definition
histo
Term
mucoid capsule under mucicarmine stain, see halo
Definition
crypto
Term
entire left lung is infarcted due to thrombosis, see vascular invasion of numerous interwinded fungal hyphae admixed with red cell, broad, irregularly branching, and nonseptate.
Definition
angioinvasive mucomycosis. from zygomycetes: mucor, rhizopus, absidia.
Term
under silver methenamine stain, see septate hyphae with 45 degree branching
Definition
aspergillus infection
Term
large aggregate of hyphae fill pre-existing cavity in lung apex see numerous round colony of fungus
Definition
aspergilloma fungus ball
Term
diffuse pulmonary hemorrhage with red cecll in alveoli, see linear staining along BM in IF.
Definition
goodpasture's syndrome
Term
fibroblast focus , subpleural interstitial fibrosis ith honeycombing and lymphocyte
Definition
idiopathic pulmonary fibrosis
Term
alveoli filled with young CT
Definition
COP/BOOP
Term
interstitial fibrosis and asbestos body
Definition
asbestosis. body is fibers coated with hemosiderin-containing proteinaceous material
Term
young cellular nodule along side older fibrotic nodule.
Definition
silicosis
Term
carbon deposition with scarring
Definition
coal workers pmeumoconiosis
Term
enlarged air space in center of upper lobe from tobacco at respiratory bronchioles.
Definition
centriacinar emphysema
Term
enlarged airspace from respiratory bronchiole distally to involve the entire acinus, alveolar septa fragmented and reduced in number
Definition
panacinar emphysema
Term
bullae airfilled greater than 1cm.
Definition
bullous emphysema
Term
inccreased thickness of bronchial submucosa, increase mucus or mucopurulent secretion increased goblet cell thickened BM, metaplasia and dysplasia
Definition
chronic bronchitis
Term
eosinophil between squamous metaplasia of respiratory mucosa and mucus glands
Definition
asthma
Term
eosinophilia in peripheral blood, migratory pulmonary infiltrate, sinusitis, in asthmatic patient
Definition
churg-strauss syndrome
Term
bronchi marketed dilated distally
Definition
bronchiectasis
Term
warty exophytic tumor originated in proximal bronchus with keratin pearls
Definition
SCC
Term
nuclear pleomorphism and hyperchromasia thru full thickness of epi but remain superficial to BM
Definition
carcinoma in situ
Term
neoplasm in periphery of lung, form glands back to back and show intracellular mucin in mucicarmine stain
Definition
adenocarcinoma
Term
silver methenamine stain: round nonseptating vs. 45 angle branching vs. intertwined fungal hyphae
Definition
histo vs. aspergillus vs. mucor
Term
resembling pneumonia or single or multiple discrete nodules, spreads along alveolar septa without disrupting as stroma, well differentiated columnar or cuboidal epi with mucin
Definition
bronchoalveolar carcinoma
Term
salt and pepper appearance cell with high nuclear:cytoplasmic ratio and small nuclei with no nucleoli
Definition
small cecll carcinoma
Term
poly poid intraluminal mass with smooth surface, form nests have uniform nuclei with little pleomorphism, few mitosis, fibrovascular stroma, chromogranin stain is brown indicate neuroendocrine cecll
Definition
carcinoid
Term
well ccircumscribed tan-white nodule has lobulated appearance, benign hyaline cartilage, adipose tissue and fibrous tissue with clefted infoldings lined by respiratory epi
Definition
hemartoma
Term
cannonball next to lymphangitic spread
Definition
meta
Term
fibrin deposit on pleural surface with rheumatoid arthritis
Definition
fibrinous pleuritis
Term
aggressive neoplasm fill the pleuralspace and compress the lung
Definition
mesothelioma
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