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Blood Dos
BLOOOD
52
Medical
Undergraduate 4
04/11/2012

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Term
anemia
Definition
deficiency in erythrocytes or hemoglobin. the most common type of anemia is iron deficiency anemia
Term
aplastic anemia
Definition
failure of blood cell production in the bone marrow. cause is unknow
Term
pancytopenia
Definition
occurs when stem cells fails to produce leukocytes, platelets and erythrocytes
Term
hemolytic anemia
Definition
reduction in red cells due to excessive destruction
Term
congenitaql spherocytic anemia
Definition
red blood cells are less biconcave and fragile
Term
pernicious anemia
Definition
lack of mature erythrocytes caused by inability to absorb vitamin B12 into the body
Term
vitamin B12
Definition
necessary for proper development and maturation of erythrocytes. It cannot be absorbed into the bloodstream without the aid of a intrinsic factor that is normally found in gastric juice
Term
sickle cell anemia
Definition
hereditary condition characterized by abnormal sickle shape of erythrocytes and by hemolysis. cannot pass through small blood vessels normally, leading t thrombosis and infarction
Term
thalassemia
Definition
inherited defect in the ability to produce hemoglobin, usually seen in persons of mediterranean background. thalassa means sea
Term
hemochromatosis
Definition
excess iron deposits throughout the body. makes you copper colored. enlarged liver
Term
polycythemia vera
Definition
general increase in red blood cells (erthremia). thick blood
Term
hemophilia
Definition
excessive bleeding caused by hereditary lack of blood clotting factors (factor VIII or IX) necessary for blood clotting
Term
purpura
Definition
multiple pinpoint hemorrhages and accumulation of blood under the skin. can be caused by have too few platelets
Term
petechiae
Definition
tiny purple or red flat spots appearing on the skin as a result of hemorrhages
Term
ecchymoses
Definition
larger blue or purplish patches on the skin (bruises)
Term
autoimmune thrombocytopenic purpura
Definition
condition in which a patient makes an antibody that destroys platelets. bleeding time is prolonged; splenectomy
Term
leukemia
Definition
increase in cancerous white blood cells . fatigue, fever, bleeding, bone pain, hepatomegaly
Term
acute myelogenous (myelocytic) leukemia (AML)
Definition
immature granulocytes predominate. platelets and erythrocytes are diminshed because of infilitration and replacement of bone marrow by large numbers of myeloblast
Term
acute lymphocytic leukemia (ALL)
Definition
immature lymphocytes predominate- most common in children and adolescents
Term
chronic myelogenous (myelocytic) leukemia (CML)
Definition
both mature and immature granulocytes and present in large numbers in the marrow and bloodstream
Term
chronic lymphocytic leukemia (CLL)
Definition
abnormal numbers of relatively mature lymphocytes pred
Term
remission
Definition
disappearance of signs and symptoms
Term
relapse
Definition
occurs when disease symptoms and signs reapper necessitating further treatment
Term
granulocytosis
Definition
abnormal increase in granulocytes in the blood
Term
eosinophilia
Definition
is an increase in eosinphilic granulocytes seen in certain allergic conditions, such as asthma or in parastitic infections
Term
basophilia
Definition
increase in basophilic granulocytes seen in certain types of leukemia
Term
mononucleosis
Definition
infectous disease markeed by increase numbers of leukocytes and enlarged cervical lymph nodes. Epstein- Barr virus
Term
multiple myeloma
Definition
malignant neoplasm of bone marrow. the malignant cells destroy bone tissue and cause overproduction of immunoglobulins, including Bence Jones protein an immunoglobulin fragment in urine
Term
palliative
Definition
relieving symptoms
Term
autologous bone marrow transplantation (ABMT)
Definition
in which the patient serves as his or her won donor for stem cells, may lead to prolonged remission
Term
antiglobulin test
Definition
test for the presence of antibodies that coat and damage erythrocytes
Term
bleeding time
Definition
time required for blood to stop flowing from a tiny puncture wound
Term
coagulation time
Definition
time required for venous blood to clot in a test tube
Term
complete blood count (CBC)
Definition
determination of numbers of blood cells, hemoglobin concentration hematocrit, and red cell values- MC, MCV, MCHC
Term
erythrocyte sedimentation rate (ESR)
Definition
speed at which erythrocytes settle out of plasma
Term
hematocrit (HcT)
Definition
percentage of erythrocytes in a volume of blood
Term
hemoglobin test (H, Hg, Hgb,HGB)
Definition
total amount of hemoglobin in a sample of peripheral blood
Term
platelet count
Definition
number of platelets per cubi millimeter or microliter of blood
Term
prothrombin time (PT)
Definition
test of the ability of blood to clot
Term
red blood cell count (RBC)
Definition
number of erythrocytes per cubic millimeter or microliter of blood
Term
red blood cell morphology
Definition
microscopic examination of a stained blood smear to determine the shape of individual red cells
Term
white blood cell count (WBC)
Definition
number of leukocytes per cubic millimeter or microliter of blood
Term
white blood cell differential count
Definition
percentages of different types of leukocytes in the blood
Term
"shift to the left"
Definition
describes an incerase in inmature neutrophils in the blood
Term
apheresis
Definition
separation of blood into component parts and removal of a select poriton from the blood
Term
blood transfusion
Definition
whole blood or cells are taken from a donor and infused into a patient
Term
autologous transfusion
Definition
collection and later reinfusion of a patients own blood or blood components
Term
packed cells
Definition
preparation of red blood cells separation from liquid plasma and administered in severe anemia t restore levels of hemoglobin and red cells without overfiluting the blood with excess fluid
Term
bone marrow biopsy
Definition
microscopic examination of a core of bone marrow removed with a needle
Term
hematopoietic stem cell transplantation
Definition
peripheral stem cells from a compatible donor are administered to a recipient
Term
allogeneic transplantation
Definition
in hwich a relative or unrelated person having a close or identical HLA type is the donor
Term
autologous transplantation
Definition
stem cells or bone marrow cells are removed from the patient during a remission phase and given back to the patient after intensive chemotherapy (drug treatment)
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