Term
| What are the three general functions of blood? |
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Definition
- Transport
- Immune Response
- Coagulation
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Term
| In a 70kg male, how much blood on average will that person have? |
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Definition
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Term
| If you have a lean body mass, you have less blood, true or false? |
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Definition
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Term
| What are the two components of blood? |
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Definition
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Term
| What two things is plasma comprised of? |
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Definition
- Water (90%)
- Proteins and solutes (10%)
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Term
| What are some functions of Albumins? |
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Definition
| Maintaining osmotic pressure, as a buffer, to bind and transport insoluble substances, some are hormones, some are coagulation factors |
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Term
| What are the three main types of cells found in the blood? |
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Definition
| White blood cells, Red blood cells, Platelets |
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Term
| Do all the cells found in the blood originate from the same progenitor cells? |
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Definition
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Term
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Definition
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Term
| How can you separate the components of Blood? |
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Definition
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Term
What fraction of haematocrit is taken up by Red Blood Cells in:
Males
Females |
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Definition
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|
Term
Males = 0.40-0.54
Females = 0.37-0.47 |
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Definition
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Term
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Definition
| Having few Red Blood Cells |
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Term
| What is wrong with you if you are Polycythemic? |
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Definition
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Term
| What is the reason for the main difference in Red Blood Cell amount in men and women? |
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Definition
| The presence of Testosterone |
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Term
| What are the two main groups of White Blood Cells and what defines them? |
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Definition
- Granulocytes - Multi-nuclear
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Term
| What is the largest type of White Blood Cell? |
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Definition
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Term
| What are the major difference between Lymphocytes and Monocytes? |
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Definition
| Lymphocytes have a large rounded nucleus and produce antibodies. Monocytes have a horseshoe shaped nucleus and are phagocytic. |
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Term
| Red Blood Cells are rigid, true or false? |
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Definition
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Term
| What is the production of Red Blood Cells known as? |
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Definition
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Term
| What is the production of Red Blood Cells stimulated by? |
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Definition
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Term
| What is the life span of a Red Blood Cell? |
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Definition
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Term
| What removes dead or damaged Red Blood Cells? |
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Definition
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Term
| What is the process by which Platelets and Thrombocytes are created called? |
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Definition
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Term
| What are the three main causes of Anaemia? |
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Definition
- Decreased Red Blood Cell production
- Increased Red Blood Cell destruction
- Bleeding
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Term
| What three steps does the blood take when an injury occurs? |
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Definition
- Constriction of blood vessels
- Formation of platelet plug
- Formation of a blood clot
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Term
| What are the unique parts of the Extrinsic Coagulation pathway? |
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Definition
Tissue damage --> Tissue Factor
Tissue Factor + Factor VII --> Factor X |
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Term
| What are the unique parts of the Intrinsic blood coagulation pathway? |
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Definition
Cotact with damaged blood vessel --> Actiated factor XII
Factor XII --> Activated factor X |
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Term
| What is the cascade pathway that both the Intrinsic and Extrinsic Blood Coagulation pathways have in common? |
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Definition
Factor X --> Prothrombin
Prothrombin + Prothrombin activator + Calcium --> Thrombin
Thrombin + Fibrinogen --> Fibrin
Fibrin --> Blood clot |
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Term
| In blood vessels, what opposes Clot formation? |
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Definition
| Smooth endothelial surface, Tissue factor pathway inhibitors, Thrombin inhibition, Asprin |
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Term
| How is a blood clot dissolved? |
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Definition
Tissue-plasminogen activator (t-PA) --> plasminogen
Plasminogen --> Plasmin
Plasmin --> break down of fibrinogen |
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Term
| How many genes are the four different blood groups caused by? |
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Definition
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Term
| People with AB blood can safley recieve blood from people with what type(s) of blood? |
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Definition
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Term
| People wih O type blood can recieve blood from which type(s) of blood? |
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Definition
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Term
| What is the the Rhesus system? |
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Definition
| People with a 'D-antigen' (positive and negative) |
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Term
| What complications can arise from a Rh- mother have Rh+ children? |
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Definition
| First baby the mother will develop antibodies to the D-antigen. When the second baby is developing, these antibodies will attack the blood of the developing foetus, as they can cross the placenta |
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