Term
| What is the most common benign bone tumor? |
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Definition
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Term
| What is the most common malignant bone tumor? |
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Definition
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Term
| What is the most common primary malignant bone tumor? |
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Definition
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Term
| What is the second most common primary malignant bone tumor? |
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Definition
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Term
| What diagnostic test must be done prior to beginning treatment for bone tumors? |
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Definition
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Term
| What are the three benign reactive conditions that can mimic bone tumors? |
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Definition
Aneurysmal bone cyst
Fibrosis Dysplasia
Brown Tumor of Bone |
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Term
| What age group and sex are Aneurysmal bone cysts common in? |
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Definition
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Term
| What is the most common location for Aneurysmal bone cysts? (2) |
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Definition
metaphysis of long bone
spine |
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Term
| What is the characteristic finding in a patient with aneurysmal bone cysts? |
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Definition
| multiple cysts filled with blood |
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Term
| Where is fibrous dysplasia mostly located in the body? |
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Definition
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Term
| What gene is often mutated in fibrous dysplasia? |
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Definition
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Term
| What does the mutation in the gene involved in fibrous dysplasia lead to? (2) |
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Definition
endocrine problems
fibroblast proliferation forming lesions |
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Term
| What are the three classification categories of fibrous dysplasia? |
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Definition
monostotic
polyostotic
McCune Albright |
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Term
| What unique clinical feature is present in the McCune Albright presentation of fibrous dysplasia? |
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Definition
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Term
| What is the histological feature of fibrous dysplasia? |
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Definition
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Term
| What is the brown tumor of bone caused by? |
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Definition
metabolic bone disease
increased PTH |
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Term
| What bone disease presents with frontal sinus involvement? |
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Definition
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Term
| What other condition is often associated with osteoma? |
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Definition
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Term
| Give two examples of benign bone tumors? |
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Definition
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Term
| What is the classic clinical presentation of osteiod osteoma? |
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Definition
| increased pain at night with ASA relief |
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Term
| What are the most common bones for osteiod osteoma to involve? |
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Definition
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Term
| What is true of the size of the lesions in osteiod osteoma? |
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Definition
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Term
| What does the osteiod osteoma tumor produce? |
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Definition
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Term
| What bone tumor presents with a bulls eye on Xray? |
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Definition
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Term
| What happens to the bone in a patient with osteiod osteoma? and what type of bone? |
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Definition
| get dense sclerotic nidus (woven bone) |
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Term
| What age and sex is osteosarcoma most common in? |
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Definition
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Term
| What is the common location for osteosarcoma in the bone itself? |
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Definition
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Term
| What joint is most effected by osteosarcoma? |
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Definition
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Term
| What is the unique pathology of osteosarcoma? |
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Definition
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Term
| What is codman's Triangle? |
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Definition
| when the periosteum is raised |
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Term
| Is codman's triangle beinign or malignent? |
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Definition
| benign despite the fact that osteosarcoma is malignent |
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Term
| What cell produces the osteoid in osteosarcoma? |
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Definition
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Term
| What is true of the prognosis trend in osteosarcoma? |
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Definition
| it has inproved over the years |
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Term
| What are three diseases and one treatment put you at risk of secondary and primary osteosarcoma, respectively? |
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Definition
Retinoblastoma
Pagets
fibrous dysplasia
Radiation therapy |
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Term
| What is the most common location for osteochondroma involvement? |
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Definition
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Term
| What often forms in an osteochondroma? |
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Definition
| bony outgrowth from cortical surface that is covered in cartilage |
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Term
| Give two examples of cartilage forming benign tumors? |
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Definition
osteochondroma
Enchondroma |
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Term
| Do the cartilage producing benign tumors have a high or low potential for becoming malignant? |
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Definition
|
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Term
| What is the common location for encondroma to effect? |
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Definition
distally,
the hands and feet |
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Term
What are the most common location for chondrosarcoma?
(2) |
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Definition
proximal long bones
axial skeleton |
|
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Term
| What location within the bone does enchondroma effect? |
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Definition
|
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Term
| What type of cartilage is produced in an enchondroma tumor? |
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Definition
|
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Term
| What is the common age and sex for chondrosarcoma? |
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Definition
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Term
What are the common age and sex for the following:
Aneurysm Bone Cysts
Osteosarcoma
Chondrosarcoma
Giant Tumor Cell
Ewing Sarcoma |
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Definition
Aneurysm Bone Cysts young female
Osteosarcoma young male
Chondrosarcoma adult male
Giant Tumor Cell adult female
Ewing Sarcoma childhood and adolescent male |
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Term
| What grade are most chondrosarcomas? |
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Definition
|
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Term
| What is the most common location of metastatic chondrosarcoma? |
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Definition
|
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Term
| What is true of the cells often found in chondrosarcoma? |
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Definition
|
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Term
| What two categories of chondrosarcomas exist/where they effect in the bone? |
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Definition
intramedullary (central)
on the surface (periphery) |
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Term
| What is the characteristic of the medullary cavity in central chondrosarcoma? |
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Definition
| glistening bluish transluscent mass |
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Term
| What is the most common sex and age of Giant Tumor Cell? |
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Definition
|
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Term
| What is the most common location in the bone and what is the most common type of bone effected by Giant Tumor Cell? |
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Definition
|
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Term
| What does the Giant Tumor cell often get confused with? |
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Definition
|
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Term
| Is Giant Tumor Cell indolent or aggressive? |
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Definition
|
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Term
| IS Giant Tumor cell malignent or benign? |
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Definition
|
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Term
| What is the prognosis for Giant Tumor Cell? |
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Definition
|
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Term
| What is seen on the xray of giant cell tumor? |
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Definition
| thined cortex with expansile mass |
|
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Term
What is the most common cancer that bone cancer arises from in men?
women? |
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Definition
|
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Term
| Other than the breast and prostate, what other cancers do secondary bone tumors come from? |
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Definition
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Term
| What is the most common age and sex of Ewings Sarcoma? |
|
Definition
| childhood and adolescent males |
|
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Term
| What is the most common location for Ewing Sarcoma? |
|
Definition
| medullary cavity of diaphysis |
|
|
Term
| What is the genetic translocation present in Ewing's Syndrome? |
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Definition
|
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Term
| What disease presents with bone pain, tenderness, fever, increased sed rate, and leukocytosis? |
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Definition
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Term
| What disease, which is a better prognosis needs to be r/o in a patient suspected of having Ewings Sarcoma? |
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Definition
|
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Term
| What is the characteristic finding on an Xray for Ewings sarcoma? |
|
Definition
onion skin
this is due to the sarcoma causing a periosteal reaction due to the rapid division |
|
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Term
| What sarcoma is a primitave neuroectodermal tumor (PNET) |
|
Definition
|
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Term
| What is true of the cells in Ewing Sarcoma? |
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Definition
| small round and blue tumor cells |
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