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Cardiac
Cardiac Physiology
14
Physiology
Undergraduate 2
11/12/2012

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Cards

Term
Cardiac muscle fibers are interconnected by intercalated discs. They form a functional syncytia that is:
Definition
myogenic
Term
Depolarization in heart is due to
Definition
Decreased outward K+ current
Term
Depol and repol due to:
Definition
L-type Ca++ channels and voltage-activated K+ channels
Term
To increase HR:
Definition
Decrease K conductance
Term
complete heart block
Definition
atria 70 bpm; ventricles 30 bpm
Term
too much extracellular K+ ==>
Definition
depolarize cell, ectopic foci and arrhythmias, stop heart
Term
Verapamil
Definition
blocks Ca influx to reduce contraction force
Term
Digitalis
Definition
Increase extracellular CA (increase contraction strength)
Term
Isovolumetric ventricular contraction
Definition
contraction w/o change in bld vol of heart
Term
Isovolumetric Ventricular Relaxation
Definition
no bld movement from atrium into vents until pressure is lower in vents than atrium
Term
Norepinephrine released from sympathetic nerves bind___
Definition
B1 adrenergic receptrorc causing a decrease in K+ permeability in the SA node by accelerating inactivation of K+ channels
Term
Acetlycholine_____ K+ permeability of SA node by_____. Results in___
Definition
increases; slowing closure of K+ channels. Decreased HR
Term
Frank-Starling Law of the heart
Definition
increased venous return results in increased stroke vol
Term
Adenosine
Definition
mediates vasodilation
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