Term
| tyrosine hydroxylase inhibitors |
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Definition
| for pheochromocytoma (Pheochromocytoma is a rare catecholamine-secreting tumor derived from chromaffin cells) |
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Term
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Definition
| treats Hypertension (by blocking DA and NE transport into synaptic vesicles ie blocking VMAT. they are hence degraded by MAO) |
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Term
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Definition
| Treats Hypotension, heart failure. Alpha selective; Increases TPR, Reflex bradycardia |
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Term
| oxymetazoline (a1 agonist) |
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Definition
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Term
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Definition
| a2 agonist to treat chronic pain, hypertension |
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Term
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Definition
| antidepressant (blocks PM transporter; NE > 5HT) |
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Term
|
Definition
| antidepressant (blocks PM transporter): NE>5HT |
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Term
|
Definition
| to suppress appetite (Blocks PM transporter; NE >> 5HT) |
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Term
| Methylphenidate (Ritalin) |
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Definition
| for ADHD (Blocks PM transporter; DA>NE>>5HT) |
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Term
|
Definition
| Blocks PM transporter: NE = 5HT = DA |
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Term
|
Definition
| Blocks PM transporter: NE = DA >> 5HT |
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Term
| Taking aged cheese, beer, yeast products and red wine -- ie ingesting tyramine: can cause sympathetic overactivation and hypertensive crisis in patients on this drug |
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Definition
| nonselective MAO inhibitors (but not selective MAO-A or MAO-B inhibitors) |
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Term
|
Definition
| short acting nasal decongestant aerosols (a1 agonist) |
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Term
|
Definition
| long-acting nasal decongestant aerosol (a1 agonist) |
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Term
|
Definition
| orally administered nasal decongestants (a1 agonist) |
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Term
|
Definition
| For neurogenic orthostatic hypotension (a1 agonist) |
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Term
Norepinephrine: vasocontrictor or vasodilator effects predominate?
Causes reflex bradycardia or tachycardia? |
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Definition
Vasoconstrictor, because higher affinity for alpha than beta receptors.
Reflex bradycardia due to sharp increase in TPR due to arteriolar constriction. |
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Term
| Effect of Epinephrine (Low dose) |
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Definition
| Beta effects predominate: Vasodilation in muscle beds, lowered pulse pressure |
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Term
| Epinephrine (High dose): why is it used for anaphylactic shock? |
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Definition
| both beta and a1 agonist properties predominate; for anaphylactic shock because it is the only drug that (1)stabilizes mast cells (2) causes bronchodilation (3) increases cardiac function and blood pressure |
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Term
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Definition
| (alpha 2 agonist) sedative, analgesic for ICU patients; does not depress respiration |
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Term
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Definition
| a2 agonist; Used for spasticity; little sedation or change in blood pressure. Imidazine action important? |
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Term
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Definition
| a2 agonist used forwide-angle glaucoma: reduces aqueous humor production |
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Term
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Definition
| B2 agonist used as inhaled bronchodilator |
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Term
|
Definition
| b2 agonist: uterine relaxant frequently used for treatment of preterm labor |
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Term
|
Definition
| b2 agonist; uterine relaxant |
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Term
| Vasodilation of renal and mesenteric beds and inhibits sodium reabsorption ==> reduce blood pressure. Used only intravenously in patients w severe congestive heart failure. |
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Definition
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Term
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Definition
| dopamine agonist; treat hypertension by lowering blood pressure via vasodilation; increases renal blood flow |
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Term
| To treat essential hypertension and benign prostatic hyperplasia |
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Definition
| a1 antagonists eg Prazosin, Terazosin, Doxazosin |
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Term
| Prazosin, Terazosin, Doxazosin |
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Definition
| Treat Hypertension and Benign Prostate Hypertrophy (a1 antagonist) |
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Term
| Alfuzosin, Tamsulosin, Silodosin |
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Definition
| for Benign prostatic hypertrophy (selective alpha 1A antagonists) |
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