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Cell Phys
Ch 1
84
Biology
Graduate
06/07/2011

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Term
simple squamous
Definition
single layer of flattened cells ex. air sacs of lungs, walls of blood and lymph vessels
Term
simple cuboidal
Definition
single layer of cube-shaped cells ex. surface of ovaries, linings of ducts in kidney and certain glands
Term
simple columnar
Definition
single layer of rectangular cells ex. lining of uterus, stomach and intestines
Term
pseudostratified columnar
Definition
single layer but looks like multiple layers because nuclei are in different planes, rectangular cells ex. lining of respiratory passages
Term
stratified squamous
Definition
multiple layers of flattened cells ex. skin, oral cavity, throat, vagina and anal canal
Term
transitional
Definition
multiple layers, changes shape when organ changes shape ex. bladder, ureters and urethra
Term
exocrine
Definition
secrete substances into ducts that open onto an external or internal surface
Term
endocrine
Definition
secrete substances into tissue fluid or blood
Term
merocrine
Definition
release fluid products by exocytosis
Term
apocrine
Definition
cellular products and portion of the free ends of cells pinch off during secretion
Term
holocrine
Definition
entire cells containing secretory products disintegrate
Term
loose connective tissue
Definition
binds organs together ex. beneath the skin and epithelial tissue, between muscles
Term
adipose
Definition
protects, insulates and stores fat ex. beneath skin, around kidneys and heart, behind eyeballs
Term
gene
Definition
a segment of a DNA molecule that contains the information required for the synthesis of functional biological products whether protein or RNA
Term
ribosomal RNA
Definition
constituents of ribosomes, the cellular machines that synthesize proteins
Term
Messenger RNA
Definition
encode the amino acid sequence of one or more polypeptides specified by a gene or set of genes
Term
Transfer RNA
Definition
read the information encoded in the mRNA and transfer the appropriate amino acid to a growing polypeptide chain during protein synthesis
Term
Exonucleases
Definition
degrading nucleic acids from one end of the molecule
Term
Endonucleases
Definition
degrades at specific internal sites in a nucleic acid strand
Term
DNA polymerase
Definition
enzyme that synthesizes DNA
Term
Helicases
Definition
enzyme that moves along the DNA and separates the strands using ATP.
Term
topoisomerases (gyrases)
Definition
relieves topological stress in the helical DNA structure caused by strand separation
Term
Primases
Definition
enzymes that synthesize short segments of RNA that are ultimately removed and replaced by DNA one of the many functions of DNA polymerase I
Term
substiution
Definition
replacement of one base pair for another
Term
insertion
Definition
addition of one or more base pairs
Term
deletion
Definition
deletion of one or more base pairs
Term
silent mutation
Definition
affects nonessential DNA or has negligible effect on the function of a gene
Term
activators
Definition
increase transcription
Term
repressors
Definition
block the synthesis mRNA at specific genes
Term
splicing
Definition
removes non-coding introns
Term
triplet codon
Definition
4 nucleotides (A,C,T,G) => 43 = 64 different combinations
Term
initiation codon
Definition
AUG
Term
translocation
Definition
the ribosome moves one codon toward the 3' end the mRNA
Term
proofreadng
Definition
incorrect aminoacyl-tRNAs dissociate from the A site
Term
polysome
Definition
multiple ribosomes translating a mRNA molecule simultaneously
Term
transferrin
Definition
iron carrying protein
Term
clathrin coated pits
Definition
proteins bind to receptors in invaginations of the membrane
Term
cayeolin dependent endocytosis
Definition
causes invagination of patches of membrane containing lipid rafts associated with certain types of receptors
Term
Sarcolemma
Definition
a Thin Membrane Enclosing a Skeletal Muscle Fiber
Term
A Bands
Definition
actin and myosin overlap
Term
Z disc
Definition
attachment of the ends of actin filaments
Term
Sarcomere
Definition
portion of the myofibril (or of the whole muscle fiber) that lies between two successive Z discs
Term
simple squamous
Definition
single layer of flattened cells ex. air sacs of lungs, walls of blood and lymph vessels
Term
simple cuboidal
Definition
single layer of cube-shaped cells ex. surface of ovaries, linings of ducts in kidney and certain glands
Term
simple columnar
Definition
single layer of rectangular cells ex. lining of uterus, stomach and intestines
Term
pseudostratified columnar
Definition
single layer but looks like multiple layers because nuclei are in different planes, rectangular cells ex. lining of respiratory passages
Term
stratified squamous
Definition
multiple layers of flattened cells ex. skin, oral cavity, throat, vagina and anal canal
Term
transitional
Definition
multiple layers, changes shape when organ changes shape ex. bladder, ureters and urethra
Term
exocrine
Definition
secrete substances into ducts that open onto an external or internal surface
Term
endocrine
Definition
secrete substances into tissue fluid or blood
Term
merocrine
Definition
release fluid products by exocytosis
Term
apocrine
Definition
cellular products and portion of the free ends of cells pinch off during secretion
Term
holocrine
Definition
entire cells containing secretory products disintegrate
Term
loose connective tissue
Definition
binds organs together ex. beneath the skin and epithelial tissue, between muscles
Term
adipose
Definition
protects, insulates and stores fat ex. beneath skin, around kidneys and heart, behind eyeballs
Term
gene
Definition
a segment of a DNA molecule that contains the information required for the synthesis of functional biological products whether protein or RNA
Term
ribosomal RNA
Definition
constituents of ribosomes, the cellular machines that synthesize proteins
Term
Messenger RNA
Definition
encode the amino acid sequence of one or more polypeptides specified by a gene or set of genes
Term
Transfer RNA
Definition
read the information encoded in the mRNA and transfer the appropriate amino acid to a growing polypeptide chain during protein synthesis
Term
Exonucleases
Definition
degrading nucleic acids from one end of the molecule
Term
Endonucleases
Definition
degrades at specific internal sites in a nucleic acid strand
Term
DNA polymerase
Definition
enzyme that synthesizes DNA
Term
Helicases
Definition
enzyme that moves along the DNA and separates the strands using ATP.
Term
topoisomerases (gyrases)
Definition
relieves topological stress in the helical DNA structure caused by strand separation
Term
Primases
Definition
enzymes that synthesize short segments of RNA that are ultimately removed and replaced by DNA one of the many functions of DNA polymerase I
Term
substiution
Definition
replacement of one base pair for another
Term
insertion
Definition
addition of one or more base pairs
Term
deletion
Definition
deletion of one or more base pairs
Term
silent mutation
Definition
affects nonessential DNA or has negligible effect on the function of a gene
Term
activators
Definition
increase transcription
Term
repressors
Definition
block the synthesis mRNA at specific genes
Term
splicing
Definition
removes non-coding introns
Term
triplet codon
Definition
4 nucleotides (A,C,T,G) => 43 = 64 different combinations
Term
initiation codon
Definition
AUG
Term
translocation
Definition
the ribosome moves one codon toward the 3' end the mRNA
Term
proofreadng
Definition
incorrect aminoacyl-tRNAs dissociate from the A site
Term
polysome
Definition
multiple ribosomes translating a mRNA molecule simultaneously
Term
transferrin
Definition
iron carrying protein
Term
clathrin coated pits
Definition
proteins bind to receptors in invaginations of the membrane
Term
cayeolin dependent endocytosis
Definition
causes invagination of patches of membrane containing lipid rafts associated with certain types of receptors
Term
Sarcolemma
Definition
a Thin Membrane Enclosing a Skeletal Muscle Fiber
Term
A Bands
Definition
actin and myosin overlap
Term
Z disc
Definition
attachment of the ends of actin filaments
Term
Sarcomere
Definition
portion of the myofibril (or of the whole muscle fiber) that lies between two successive Z discs
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