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the smallest blood vessels Location of exchange between blood and interstitial fluid |
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(inner layer) Includes endothelium and surrounding CT |
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(middle layer) Smooth muscle in a framework of loose CT Muscle activity influences vessel diameter and blood flow |
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(outer layer) Connective tissue sheath, fibers typically blend into nearby tissues to anchor the blood vessel |
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occurs as smooth muscle contracts |
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occurs as smooth muscle relaxes |
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A bulge in an arterial wall Is caused by weak spot in elastic fibers Pressure may rupture vessel |
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Large vessels such as pulmonary trunk and aorta Tunica media has many elastic fibers and few muscle cells Elasticity evens out pulse force |
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Are medium sized (most arteries) Many muscle cells in tunica media |
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Are small with little/no tunica externa and thin/incomplete tunica media |
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Are the only vessels that permit exchange between blood and interstitial fluid |
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Permit diffusion of water, small solutes, and lipid-soluble materials Have very restricted permeability (tight junctions) For example, the blood–brain barrier |
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Have pores in endothelial lining Permit rapid exchange of water and larger solutes between plasma and interstitial fluid Are found in choroid plexus, endocrine organs, kidneys, intestinal tract |
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Sinusoids (Sinusoidal Capillaries) |
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Have gaps between adjacent endothelial cells that permit free exchange of water and large plasma proteins Found in liver, spleen, bone marrow, and some endocrine organs |
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a band of smooth muscle that regulates flow into the capillary |
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a joining of blood vessels |
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The cycling of contraction and relaxation of capillary sphincters Causes blood flow in capillary beds to constantly change routes |
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Folds of tunica intima Prevent backward flow |
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Heart, arteries, and capillaries contain |
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Capillary blood flow is determined by |
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Flow (F) is directly proportional to |
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Flow (F) is inversely proportional to resistance (R) |
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Arterial pressure in the systemic circuit |
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resistance to flow caused by interactions among molecules and suspended materials in a liquid |
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Whole blood viscosity is about _____ times greater than water |
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swirling action that disturbs the smooth flow of a liquid |
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As blood flows from the aorta to the capillaries, the cross-sectional area _____ and blood velocity _____ |
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Peak arterial pressure during ventricular systole |
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Minimum arterial pressure during diastole |
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Difference between systolic pressure and diastolic pressure |
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Hypertension is abnormally high BP Greater than |
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Hypotension is abnormally low BP Less than |
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Arterial walls stretch during systole and rebound (recoil to original shape) during diastole Keeps blood moving during diastole |
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the 3 most important processes driving capillary exchange |
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Diffusion, filtration, and reabsorption |
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movement of ions or molecules from areas of higher concentration to areas of lower concentration |
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is the movement of a fluid across a membrane whose pores restrict certain solutes based on their size Driven by hydrostatic pressure |
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is the return of fluids into the bloodstream |
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Net capillary hydrostatic pressure tends to |
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push water and solutes out of capillaries and into the interstitial fluid |
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Net capillary colloid osmotic pressure (plasma proteins) tends to |
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pull water and solutes into a capillary from the interstitial fluid |
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Net filtration pressure = |
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hydrostatic pressure – osmotic pressure |
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Tissue perfusion is affected by (3 things): |
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Cardiac output Peripheral resistance Blood pressure |
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