Term
What are the two types of food processing? |
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Definition
Mechanical: chewing, tearing, grinding etc
Chemical: catabolic reactions, enzymatic hydrolysis |
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Term
What are the 6 phases of food processing? |
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Definition
1. Ingestion
2. Secretion
3. Mixing and propulsion
4. Digestion
5. Absorption
6. Defecation |
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Term
What is the order of the GI tract? |
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Definition
Mouth to pharynx to esophagus to stomach to small intestine to large intestine |
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Term
What are the accessory organs of the digestive system? |
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Definition
Teeth, tongue, salivary glands, liver, gallbladder, pancreas |
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Term
What is the purpose of mucosa? |
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Definition
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Term
What is the purpose of submucosa? |
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Definition
Controls release of secretion by GI organs, extends entire length of GI tract |
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Term
What is the purpose of the muscularis? |
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Definition
Swallowing and defecation using skeletal muscle, 2 layers of smooth muscle used for compressing and mixing and peristalsis |
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Term
What is the purpose of the serosa? |
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Definition
Visceral serosa cover organs, parietal serosa line walls of abdominopelvic cavity |
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Term
What are the 4 layers of the GI tract? |
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Definition
1. Mucosa
2. Submucosa
3. Muscularis
4. Serosa |
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Term
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Definition
Falciform ligament which attaches liver to anterior abdominal wall and diaphragm |
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Term
What are the functions and components of the mouth? |
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Definition
Functions: food acquisition and chewing
Components: uvula which closes nasal cavity and vestibule which is the sapce bound by cheeks/lips and gums/teeth |
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Term
What are the 3 main sets of salivary glands? |
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Definition
Parotid, submandibular, and sublingual. |
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Term
What is the function of the salivary glands? |
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Definition
Lubricate, moisten, soften food, chemical digestion using enzymes |
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Term
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Definition
Bolus formation, speech, chewing, lingual glands, taste, papillae (some have taste buds) |
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Term
What are the parts of the teeth? |
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Definition
Dentin is the calcified CT which forms most of the tooth, enamel is the covering over the dentin, cementum and ligaments hold the tooth in the socket |
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Term
What are the 3 regions of the pharynx? |
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Definition
Nasopharynx, oropharynx, laryngopharynx, function in swallowing |
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Term
What are the functions of the esophagus and what layer of the GI tract is it? |
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Definition
Secrete mucus, transport food, composed of muscularis |
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Term
What is the mechanism of wavelike contractions that propel th ebolus down the esophagus to the stomach? |
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Definition
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Term
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Definition
Act of swallowing food, bolus moving from mouth to stomach, voluntary when the tongue forces bolus to back of the oral cavity and in oropharynx, involuntary when passing into oropharynx, involuntary when moving into esophagus |
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Term
What is Gastroesophageal Reflux Disease? |
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Definition
Also called heartburn, inadequate closure of lower esophageal sphincter, HCl from stomach irritates esophagus, chronic can bring risk of esophageal ulxers and cancer, treated with HCl secretion inhibitors |
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Term
What are the functions of the stomach? |
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Definition
Mix food, food reservoir, chemical digestion, antibacterial because acidic, absorbs B12/alcohol/water/ions/some drugs, pH of 2.5 |
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Term
What are the 4 main regions of the stomach? |
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Definition
Cardia, fundus, body, pylorus |
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Term
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Definition
Pyloric sphincter muscle abnormality |
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Term
What is pyloric stenosis? |
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Definition
Chyme prevented form moving to small intestine resulting in projectile vomiting |
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Term
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Definition
Visualization via fiber optic instruments |
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Term
What are the 3 muscle layers of the stomach? |
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Definition
Oblique, circular, longitudinal |
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Term
How is the stomach protected from gastric juice? |
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Definition
1-3 mm layer of alkaline mucus |
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Term
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Definition
Soupy liquid produced by digestion |
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Term
How long is food in the stomach? |
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Definition
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Term
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Definition
Forcible expulsion of chyme, stimulated by unpleasant sights/anesthesia/dizziness/drugs, nerve impulses sent to vomiting center in medulla oblongata |
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Term
What are the parts of the pancreas? |
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Definition
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Term
What cells are in the pancreas? |
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Definition
Langerhans cells and acini cells |
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Term
What is the pancreas regulated by? |
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Definition
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Term
What enzymes and compounds are a part of pancreatic juic? |
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Definition
Pancreatic amylase, trypsin, chymotrypsin, carboxypeptidase, pancreatic lipase, ribonuclease |
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Term
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Definition
Inflammation, trypsin digests pancreatic cells, caused by alcoholism/gallstones/cystic fibrosis/high levels of calcium or fats in blood |
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Term
What is pancreatic cancer linked to? |
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Definition
Linked to alcohol consumption/fatty foods/smoking/chronic pancreatitis |
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Term
What is the liver and its functions? |
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Definition
Largest gland, second largest organ, bile is produced by the hepatocytes, functions in metabolism of carbs/proteins/lipids, synthesis of bile salts, storage of vitamins/minerals, removal of drugs/hormones from blood, excretion of bilirubin, activates vitamin D, phagocytosis of RBC/WBC/bacteria |
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Term
What is the path of blood in the liver? |
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Definition
1. Hepatic artery or hepatic portal vein
2. Liver sinusoids
3. Central vein
4. Hepatic vein
5. Inferior vena cava
6. Right atrium of heart |
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Term
What are the functions of the gallbladder? |
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Definition
Stores and concentrates bile until needed, CCK causes ejection of bile |
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Term
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Definition
Form from crystallized cholesterol due to insufficient bile salts or excessive cholesterol, risk factors are being obese/middle aged/female, treatments include gallstone-dissolving drugs/lithotripsy/surgery |
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Term
What are the 3 regions of the small intestine? |
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Definition
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Term
What is the purpose of microvilli in the small intestine? |
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Definition
Increase surface area for absorption of nutrients |
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Term
What is segmentation in the small intestine? |
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Definition
Localized mixing contractions which mix chyme and bring it in contact with mucosa for absorption |
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Term
How does chemical digestion in the small intestine work? |
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Definition
Uses enzymes peptidase/sucrase/lactaste/maltase/lipase/nuclease, enzymatic digestion takes place at absorptive cells lining villi |
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Term
How does the small intestine play a role in absorption? |
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Definition
90% of all absorption occurs in small intestine, water absorbed by osmosis, electrolytes by active transport |
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Term
How does the nervous system affect the small intestine? |
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Definition
Parasympathetic stimulation increases motility, sympathetic stimulation decreases motility |
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Term
How does the presence of chyme affect the small intestine? |
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Definition
Increases motility/secretions |
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Term
Where does the large intestine go from? |
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Definition
Extends from ileocecal sphincter to the anus |
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Term
How does large intestinal mechanical digestion work? |
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Definition
Called haustral churning, peristalsis allows for 3-12 contractions per minute |
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Term
How does chemical digestion work in the large intestine? |
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Definition
Bacterial digestion not enzymatic, fermentation of carbs and amino acids |
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Term
How much absorption does the large intestine have? |
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Definition
Out of 9L only 1L is large intestine |
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Term
What is feces and what are the components? |
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Definition
Dehydrated chyme, components are water/inorganic salts/sloughed-off epithelial cells/bacteria/bacterial waste products |
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Term
What is the defecation reflex? |
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Definition
Elimination of feces from rectum, initiated by stretch receptors as rectum becomes filled |
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Term
What is diarrhea and constipation? |
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Definition
Diarrhea is increased motility and decreased absorption, constipation is decreased motility and increased absorption |
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Term
What are the 3 phases of digestion? |
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Definition
1. Cephalic phase
2. Gastric phase
3. Intestinal phase |
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Term
What is the cephalic phase of digestion? |
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Definition
Sights, thoughts, tastes, CN X stimulates secretion of gastric juice during this phase |
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Term
What is the gastric phase of digestion? |
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Definition
When food reaches stomach, neural and hormonal mechanisms, promotes secretion of gastric juice, increases gastric motility |
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Term
What is the intestinal phase of digestion? |
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Definition
When food enters the small intestine, neural and hormonal mechanisms, stimulates secretion of bile/pancreatic juice |
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Term
How does aging affect digestion? |
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Definition
Decreased secretions, decreased motility, loss of muscular strength and tone, reduced hormone levels |
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Term
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Definition
Tooth decay, plaque contains acid-producing bacteria, acids demineralize enamel and dentin |
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Term
What is periodontal disease? |
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Definition
Inflammation and degeneration of gingivae/alveolar bone/periodontal ligament/cementum |
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Term
What is peptic ulcer disease? |
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Definition
Craterlike lesions in GI tract, bleeding and perforation can be very serious, caused by Heliobacter pylori and aspirin and HCl hypersecretion |
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Term
What is colorectal cancer? |
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Definition
2nd deadliest cancer in males, 3rd deadliest cancer in females |
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Term
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Definition
Inflammation of liver caused by different viruses |
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Term
How is Hepatitis A trasnmitted? |
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Definition
Fecal contamination on food/clothes/toys/eating utensils, prevented by vaccine |
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Term
How is Hepatitis B trasnmitted? |
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Definition
Transmitted by sexual contact/shared needles/saliva/tears, prevented by vaccine |
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Term
What is anorexia nervosa? |
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Definition
Chronic self-induced weight loss, genetic basis, may die of starvation, treated by psychotherapy and diet regulation |
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Term
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Definition
Binge-purge syndrome, overeating followed by exercise/emesis/laxatives |
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Term
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Definition
Intestinal growling, gases moving through intestines |
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Term
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Definition
Gallbladder inflammation, blocked cystic duct by bile stones or autoimmune attack |
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Term
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Definition
Colon-rectum mucous membrane inflammation, autoimmune condition, causes diarrhea/cramps/bloody stools |
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Term
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Definition
Surgical stoma produced in body wall, diverts feces from anus to collection bag |
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Term
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Definition
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Term
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Definition
Inflammation of intestine, especially SI |
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Term
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Definition
Belching, release of stomach gas, chronic belching usually not sign of disease but a learned behavior |
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Term
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Definition
Gas expelled through anus, from carbonated drinks/swallowing air/smoking/fermentation |
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Term
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Definition
Protrusion of all or part of organ through membrane, diaphragmatic or inguinal most common |
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Term
What are the 2 inflammatory bowel diseases? |
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Definition
Chron's disease and Ulcerative colitis |
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Term
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Definition
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Term
What is ulcerative colitis? |
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Definition
Large intestine inflammation and bleeding |
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Term
What is irritable bowel syndrome? |
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Definition
Stress induced, alternating periods of diarrhea and constipation |
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Term
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Definition
Poor fit of upper and lower teeth |
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Term
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Definition
Foodborne, wound is infected by Clostridium botulinum, in infants they can consume spores of C. botulinum which grow in intestines and release the toxin |
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Term
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Definition
Painful mucous membrane ulcer, females more susceptible than males, may be food allergy or autoimmune reaction |
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Term
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Definition
Enlarged/scarred liver, caused by chronic inflammation |
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Term
What are the benefits of alcohol consumption? |
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Definition
Moderate drinking may stave off mental decline, may result in lower coronary risk, may increase angiogenesis in tumors, overall alcohol is more negative than positive |
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Term
What are treatments for nausea and vomiting? |
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Definition
Drink small amounts of clear sweetened liquids, no solid food, rest |
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