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a group of similar cells and cell products working together to perform a specific role in an organ |
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epithelial, connective, nervous, and muscular |
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how the 4 primary tissues differ from each other |
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Types and functions of their cells Characteristics of the matrix (extracellular material) Relative amount of space occupied by cells versus matrix |
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what matrix (extracellular material)is made of |
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-Fibrous proteins -Clear gel called ground substance Also known as tissue fluid, extracellular fluid (ECF), interstitial fluid, or tissue gel |
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the three primary germ layers |
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ectoderm (outer) endoderm (inner) mesoderm (middle) |
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Gives rise to epidermis and nervous system |
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Gives rise to mucous membrane lining digestive and respiratory tracts, digestive glands, among other things |
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Wispy collagen fibers and fibroblasts in gel matrix Gives rise to muscle, bone, blood |
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tissue is rubbed across a slide Example: blood |
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some membranes and cobwebby tissues are laid out on a slide Example: areolar tissue |
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(does not have blood vessels) Usually nourished by underlying connective tissue |
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layer between an epithelium and underlying connective tissue |
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surface of epithelial cell facing the basement membrane |
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surface of epithelial cell that faces away from the basement membrane |
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Contain one layer of cells Named by shape of cells All cells touch basement membrane |
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Contain more than one layer Named by shape of apical cells Some cells rest on top of others and do not touch basement membrane |
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epithelia with only one layer |
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Simple squamous (thin, scaly cells) Simple cuboidal (square or round cells) Simple columnar (tall, narrow cells) Pseudostratified columnar |
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wineglass-shaped mucus-secreting cells in simple columnar and pseudostratified epithelia |
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simple squamous epithelia |
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Single row of thin cells Permits rapid diffusion or transport of substances Secretes serous fluid Locations: alveoli, glomeruli, endothelium, and serosa |
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simple cuboidal epithelia |
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Single layer of square or round cells Absorption and secretion, mucus production and movement Locations: liver, thyroid, mammary and salivary glands, bronchioles, and kidney tubules |
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simple columnar epithelia |
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Single row of tall, narrow cells Oval nuclei in basal half of cell Brush border of microvilli, ciliated in some organs, may possess goblet cells Absorption and secretion; secretion of mucus Locations: lining of GI tract, uterus, kidney, and uterine tubes |
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pseudostratified epithelia |
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Looks multilayered, but all cells touch basement membrane Nuclei at several layers Has cilia and goblet cells Secretes and propels mucus Locations: respiratory tract and portions of male urethra |
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Range from 2 to 20 or more layers of cells |
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most widespread epithelium in the body |
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found on skin surface, abrasion resistant |
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lacks surface layer of dead cells |
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keratinized stratified squamous |
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Multiple cell layers; cells become flat and scaly toward surface Resists abrasion; retards water loss through skin; resists penetration by pathogenic organisms Locations: epidermis; palms and soles heavily keratinized |
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nonkeratinized stratified squamous |
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Same as keratinized epithelium without surface layer of dead cells Resists abrasion and penetration of pathogens Locations: tongue, oral mucosa, esophagus, and vagina |
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stratified cuboidal epithelium |
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Two or more cell layers; surface cells square or round Secretes sweat; produces sperm, produces ovarian hormones Locations: sweat gland ducts; ovarian follicles and seminiferous tubules |
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Multilayered epithelium with surface cells that change from round to flat when stretched Allows for filling of urinary tract Locations: ureter and bladder |
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a diverse, abundant type of tissue in which cells occupy less space than matrix |
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produce fibers and ground substance of matrix |
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phagocytize foreign material and activate immune system when they sense foreign matter (antigens) |
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synthesize antibodies (proteins) |
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often found alongside blood vessels Secrete heparin to inhibit clotting Secrete histamine to dilate blood vessels |
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the fibers of fibrous connective tissue |
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collagenous reticular elastic |
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Long polysaccharides composed of amino sugars and uronic acid (disaccharides) Regulate water and electrolyte balance of tissues |
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Much gel-like ground substance between cells Types Areolar Reticular |
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Fibers fill spaces between cells Types vary in fiber orientation Dense regular connective tissue Dense irregular connective tissue |
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loosely organized fibers, abundant blood vessels, and a lot of seemingly empty space |
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Loosely organized fibers, abundant blood vessels Underlies epithelia, in serous membranes, between muscles, passageways for nerves and blood vessels |
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Mesh of reticular fibers and fibroblasts Forms supportive stroma (framework) for lymphatic organs Found in lymph nodes, spleen, thymus, and bone marrow |
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dense regular connective tissue |
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Densely packed, parallel collagen fibers Compressed fibroblast nuclei Elastic tissue forms wavy sheets in some locations Tendons attach muscles to bones and ligaments hold bones together |
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dense irregular connective tissue |
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Densely packed, randomly arranged, collagen fibers and few visible cells Withstands unpredictable stresses Locations: deeper layer of skin; capsules around organs |
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main type (only fat in adults) |
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in fetuses, infants, children |
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cartilage cells that produce the matrix that will trap them |
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cartilage cells that are trapped in lacunae (cavities) |
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sheath of dense irregular connective tissue that surrounds elastic and most hyaline cartilage (not articular cartilage) |
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sheath of dense irregular connective tissue that surrounds elastic and most hyaline cartilage (not articular cartilage) |
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No blood vessels Diffusion brings nutrients and removes wastes Heals slowly |
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Clear, glassy appearance because of fineness of collagen fibers Eases joint movement, holds airway open, moves vocal cords, growth of juvenile long bones Locations: articular cartilage, costal cartilage, trachea, larynx, fetal skeleton |
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Cartilage containing abundance of elastic fibers Covered with perichondrium Provides flexible, elastic support Locations: external ear and epiglottis |
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Cartilage containing large, coarse bundles of collagen fibers Resists compression and absorbs shock Locations: pubic symphysis, menisci, and intervertebral discs |
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calcified connective tissue |
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porous appearance Delicate struts of bone: trabeculae Covered by compact bone Found in heads of long bones and in middle of flat bones such as the sternum |
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denser, calcified tissue with no visible spaces More complex arrangement Cells and matrix surround vertically oriented blood vessels in long bones |
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arranged in cylinders that surround central (haversian or osteonic) canals that run longitudinally through shafts of long bones |
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Onion-like layers around each central canal |
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central canal and its surrounding lamellae |
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mature bone cells within lacunae |
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delicate canals radiating from each lacuna to its neighbors, allowing osteocytes to contact each other |
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tough fibrous connective tissue covering the whole bone |
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ability to respond to stimuli by changing membrane potential |
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electrical charge difference (voltage) that occurs across the cell membrane |
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specialized for communication by electrical and chemical signals |
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Protect and assist neurons “Housekeepers” of nervous system More numerous than neurons |
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Detect stimuli Respond quickly Transmit coded information rapidly to other cells |
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(cell body) Houses nucleus and other organelles Controls protein synthesis |
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Multiple short, branched processes Receive signals from other cells Transmit messages to neurosoma |
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(nerve fiber) Sends outgoing signals to other cells Can be more than a meter long |
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elongated cells that are specialized to contract in response to stimulation |
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skeletal, cardiac, and smooth |
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Primary job is to exert physical force on other tissues and organs |
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Made of muscle fibers—long thin cells |
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Limited to the heart Myocytes or cardiocytes are branched, shorter than skeletal muscle fibers Contain one centrally located nucleus |
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Made of fusiform myocytes lacking striations Cells are relatively short and have one central nucleus Involuntary function Most is visceral muscle—making up parts of walls of hollow organs |
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connections between two cells |
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linkage between two adjacent cells by transmembrane cell-adhesion proteins |
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patch that holds cells together (like a clothing snap) |
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half desmosomes that anchor basal cells of an epithelium to underlying basement membrane |
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formed by ring-like connexons |
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cell or organ that secretes substances for use elsewhere in the body or releases them for elimination from the body |
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maintain their contact with surface of epithelium by way of a duct |
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have no ducts; secrete hormones directly into blood |
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chemical messengers that stimulate cells elsewhere in the body |
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found in an epithelium that is predominantly nonsecretory |
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connective tissue covering of exocrine gland |
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extensions of capsule that divide interior of gland into compartments (lobes and lobules) |
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connective tissue framework of the gland |
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cells that perform the tasks of synthesis and secretion |
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Tubular: narrow secretory portion Acinar: secretory cells form dilated sac (acinus or alveolus) Tubuloacinar: both tubular and acinar portions |
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Produce thin, watery secretions |
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Produce glycoprotein, mucin, which absorbs water to form mucus |
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Contain both serous and mucous cell types and produce a mixture of the two types of secretions |
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Release whole cells (sperm and egg cells) |
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(used by eccrine glands) uses vesicles that release their secretion by exocytosis |
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lipid droplet covered by membrane and cytoplasm buds from cell surface |
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cells accumulate a product until they disintegrate |
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cutaneous membrane (the skin) |
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largest membrane in the body |
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lines passages that open to the external environment (example: digestive tract) |
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sublayers of mucous membrane |
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epithelium, lamina propria (areolar tissue), muscularis mucosa (smooth muscle) |
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growth through cell multiplication |
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enlargement of preexisting cells |
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development of more specialized form and function by unspecialized tissue |
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Changing from one type of mature tissue to another |
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undifferentiated cells that are not yet performing any specialized function |
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ability of a stem cell to give rise to a diversity of mature cell types |
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have potential to develop into any type of fully differentiated human cell including accessory organs of pregnancy |
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can develop into any type of cell in the embryo (but not accessory organs of pregnancy) |
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replacement of dead or damaged cells by the same type of cell as before |
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replacement of damaged cells with scar tissue |
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shrinkage of a tissue through loss in cell size or number |
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pathological tissue death due to trauma, toxins, or infections |
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artificial production of tissues and organs in the lab for implantation in the human body |
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