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All the DNA in a cell
Can consist of a single DNA molecule (common in prokaryotic cells) ot a number of DNA molecules (common in eukaryotic cells) |
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Nonreproductive cells that have two sets of chromosomes |
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Reproductive cells
Have hals as many chromosomes as somatic cells |
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A complex of DNA and protein that condenses during cell division
Make up the chromosomes |
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An apparatus of microtubules that controls chromosome movement during mitosis
Assembly begins in the centrosome during prophase |
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The product of chromosome splitting during cell division |
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The narrow "waist" of duplicated chromosomes where two chromatids are most closely attached
[image] |
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The division of the nucleus [image] |
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The division of the cytoplasm
Is well under way by late telophase
[image] |
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A variation of cell division that produces gametes
Yields nonidentical daughter cells that only habe one set of chromosomes, half as many as the parent cell |
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A section of the cell cycle that consists of mitosis and cytokineses [image] |
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A section of the cell cycle during which cell growth and copying of chromosomes in preperation of cell division takes place
Takes up approximately 90% of the cell cycle
Can be divided into 3 subphases:
G1 Phase (first gap) -
S Phase (synthesis) -
G2 phase (second gap)
The cell grows during all three phases, but chromosomes are duplicated only during the S phase
[image] |
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-Prophase
-Prometaphase - spindle microtubules attach to the kinetochores of the chromosomes and begin to move the chromosomes
-Metaphase - A stage of mitosis at which the chromosomes are all lined up at the metaphase plate
-Anaphase A stage of mitosis during which sister chromatids seperate and move along the kinetochore microtubules toward the opposite ends of the cell
-Telophase A stage of mitosis during which genetically identical daughter nuclei form at opposite ends of the cell (Cytokinesis is well underway at this point) |
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The microtubule organizing center
Replicates, forming two centrosomes that migrate to opposite ends of the cell, as spindles of microtubules grow out of them
[image] |
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A radial array of short microtubules that extends from each centrosome
Is included in the spindle, along with the centrosomes and sprindle microtubules
[image] |
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A phase of mitosis, during which spindle microtubules attach to the kinetochores of the chromosomes and begin to move the chromosomes[image] |
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A stage of mitosis at which the chromosomes are all lined up at the metaphase plate
Def: The midway point between the spindles two poles[image] |
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A stage of mitosis during which sister chromatids seperate and move along the kinetochore microtubules toward the opposite ends of the cell
The microtubules shorten by depolymerizing their kinetochore ends
[image] |
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The midway point between the spindle's two poles at which the chromosomes are lined up during metaphase
[image] |
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A stage of mitosis during which genetically identical daughter nuclei form at opposite ends of the cell [image] |
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The process of cytonikesis in animal cells
Forms a cleavage furrow
[image] |
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What is grown between sperating plant cells in cytokinesis
[image] |
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A type of cell duvision used by prokaryotes in which chromosomes replicate (beginning at the origin of replication) and the two daughter cells actively move apart
Def: The particular location in a genome from which synthesis begins
Since prokaryotes evolved before eukaryotes, mitosis probably evolved from binary fission
Certain protists exhibit types of cell division that seem intermediate between binary fission and mitosis[image] |
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Cell Cycle Control System
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The system that regulates the sequential events of the cell cycle
Regulated by both internal and external controls
Would appear to be driven by specific chemical signals present in the cytoplasm
Has specific checkpoints where the cell cycle stops until a go-ahead signal is received
For many cells, the G1 checkpoint seems to be the most important one
If a cell receives a go-ahead signal at G1, it will usually complete S, G2 and M phases and divide
If a cell does not receive the go-ahead signal, it will exit the cycle, switching into a nondivided state called the G0 phase
[image] |
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a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes.
[image] |
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MPF (maturation-promoting factor) |
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A cycline-CDK complex that triggers a cell's passage past the G2 checkpoint into the M phase |
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Proteins released by certain cells that stimulate other cells to divide |
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Density-Dependent Inhibition |
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An external signal that prompts crowded cells to stop growing
Cancer cells do not exhibit this
[image] |
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Cells must be attached to a substratum in order to divide
Cancer cells do not exhibit this
[image] |
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