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anerobic pre. eukaryotic cell endocytosed aerobic cell |
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prokaryotic cell (DNA) NO NUCLEUS |
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transportation through compartments |
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Definition
1. GATED-in and out of the nucleus 2. TRANSMEMBRANE- whole molecule are moved 3. VESSICULAR- small molecules |
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in and out of nucleus proteins regulated |
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from cytosol to E.R whole molecules are moved |
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small molecules are moved we package cargo vessicles bud off |
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regulate membrane transports |
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gated-in and out of nucleus |
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nucleus has pores / complex |
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each complex moves 500 molecules/sec |
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PROTEINS OF NUCLEAR MEMBRANE |
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cytosolic fibres- transport molecules and cargo lock in over all shape -octagon shape |
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Span membrane. link cytosolic structures to nuclear structures |
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interact with cloumn and intermembrane space |
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extend into pore, gating mechanism |
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Extend into nucleus linked together as nuclear basket |
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is highly selective 5KDa passes freely |
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bind to NLS TO mediate proteins comming in and out |
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help in directionality need accesory molecule function diff than ATPase is in nucleus and cytosol |
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translocase of outer mito. membrane |
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beta - barrel in outter membrane |
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TIM 23-transport of mito. matrix protein TIM 22- " of inner membrane protein |
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SORTING PROTEINS PROTEIN SYNTHESIS has ribosomes attached connected to nuclear membrane |
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detoxification mediates b/w golgi and RER sterin production and lipid synthesis |
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1. CO-TRANSLATION translocation- protein syntesis and polypeptied transport occur same time 2. POST- TRANSLATION TRANSLOCATION- Protein synths. firts polypep. transport later |
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cytosolic protein determins if ribosome binds |
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