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- extends from Foramen Magnum to the level of the disk betweenL1/L2 vertebrae - provides nervous pathways for nerve impulses between thePeripheral Nervous System and the Brain - provides simple integrative functions (reflexes) - 31 pair of spinal nerves come off of the cord to exitthrough the intervertebral foramen |
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- outer most layer - anchors the meninges with in the spinal canal - Epidural Space = lies outside the Dura that is filledwith fat and other connective tissues |
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lies outside the Dura that is filledwith fat and other connective tissues |
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- middle layer - Subdural Space = lies outside of the arachnoid mater,contains interstitial fluid (lymph) |
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- covers the surface of the Brain and Spinal Cord - Subarachnoid Space = lies outside of the Pia, containsCerebral Spinal Fluid (CSF) |
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lies outside of the arachnoid mater,contains interstitial fluid (lymph) |
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Fluid (CSF) - Denticulate ligaments = |
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thickened Pia Mater thatprojects laterally to fuse with the Dura Mater, actsas a shock absorber |
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- located between C4 and T1 vertebrae - supplies nerves to the upper extremities |
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- located between T9 and T12 vertebrae - supplies nerves to the lower extremities |
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- located between L1 and L2 vertebrae - the end of the spinal cord |
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- a fibrous band of Pia that extends from the Conus Medullaristo the Coccyx - anchors the spinal cord |
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- contains the nerves that leave the spinal cord then runinferiorly to exit from lower Intervertebral foramen |
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- is mostly white matter (myelinated fibers) providing nerveimpulse transmission to and from the Brain - contains Posterior, Lateral and Anterior Columns - Anterior Median Fissure - Posterior Median Sulcus |
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- contains gray matter (non-myelinated neurons) - provides integrative functions - contains the Anterior and Posterior Horns - Gray Commissure and Central Canal (filled with CSF) |
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- made up of sensory neurons - enters into the Posterior Horns |
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contains the cell body's of thesensory neurons Ganglion = a group of neuron cell bodies located outside theCNS |
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- made up of motor neurons - exits from the Anterior Horns |
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- combination of Dorsal and Ventral Roots (a mixed nerve) thatcome together in the intervertebral foramen |
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- located in the Columns of the spinal cord |
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a bundle of nerve axons in the CNS (as opposed to anerve which is located outside the CNS) |
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Lateral and Anterior Spinothalamic Tracts |
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- convey nerve impulses assoc. with pain, temperature change, deep pressure, |
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- convey nerve impulses assoc. with proprioception (positionsense), discriminitive touch, two point discrimination,light pressure, vibration |
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a fast, involuntary, unplanned sequence of actionsthat occur in response to a particular stimulus |
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- the pathway followed by nerve impulses that produce a reflex |
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- a structure that responds to a specific stimulus |
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- carrys the nerve impulse to the spinal cord |
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- located in the gray matter |
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a. Sensory Receptor b. Sensory Neuron c. Integrating Center d. Motor Neuron e. Effector |
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- simplest type - the sensory neuron synapses directly with themotor neuron |
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- assoc. with two or more synapses - assoc. with Interneuron (a neuron located in thespinal cord) involvement |
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- carrys the nerve impulse away from the spinal cord. |
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- the body part that responds to the nerve impulse - ex. muscle |
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- causes contraction of skeletal muscle in response tostretching of the muscle |
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- the sensory impulse enters the spinal cord on the same sidethat the motor impulse will leave (a monosynaptic reflex) - ex. a stretch reflex |
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- this prevents conflict between opposing muscles - while the agonist contracts the antagonist is inhibited |
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- leads to muscle relaxation when the stretch on tendons maylead to damage |
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Flexor (Withdrawal) Reflex |
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- assoc. with withdrawal from a negative (painful) stimulus |
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Intersegmental Reflex Arc |
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- the sensory impulse enters the spinal cord then ascends ordescends in the cord |
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- assoc. with extension of joints on one side of the bodywhile the flexors are contracting in the contralateralmuscle |
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- nerve impulses enter the cord, cross over in the GrayCommissure, then exit on the opposite side of the cord |
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1. Endoneurium 2. Perineurium 3. Epineurium |
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1. - surrounds individual nerve fibers 2. - surrounds bundles of nerve fibers - Fascicle = bundle of nerve fibers 3. - surrounds a group of fascicles = Nerve - this layer is continuous with the Dura Mater of the spinalcord |
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1. Endoneurium 2. Perineurium 3. Epineurium |
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1. - surrounds individual nerve fibers 2. - surrounds bundles of nerve fibers - Fascicle = bundle of nerve fibers 3. - surrounds a group of fascicles = Nerve - this layer is continuous with the Dura Mater of the spinalcord |
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- innervates deep muscles and skin of the dorsal trunk |
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- innervates limb muscles, and skin of the extremitiesand the remaining trunk |
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- innervates limb muscles, and skin of the extremitiesand the remaining trunk |
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- reenters the spinal cord to supply innervation tospinal cord structures |
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- Autonomic Nervous System innervation |
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Branch = Ramus (pl. Rami) |
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- the spinal nerves divide into branches after leaving the Intervertebral Foramen |
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Branch = Ramus (pl. Rami) parts: |
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Dorsal Ramus - innervates deep muscles and skin of the dorsal trunk b. Ventral Ramus - innervates limb muscles, and skin of the extremitiesand the remaining trunk c. Meningeal Branch - reenters the spinal cord to supply innervation tospinal cord structures d. Rami Communicantes - Autonomic Nervous System innervation |
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- a network of nerves - ventral rami |
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a. Cervical Plexus (C1 - C5) - the Phrenic Nerve (C3 - C5) which innervates theDiaphragm b. Brachial Plexus (C5 - T1) - supplies innervation to the shoulder and upper limb c. Lumbar Plexus (L1 - L4) - supplies part of the abdominal walls, externalgenitalia, and part of the proximal lower limb d. Sacral Plexus (L4 - S4) - supplies innervation to the lower limb - Sciatic Nerve (L4 - S3) = largest nerve in the bodywhich is made up of two separate nerves (Tibial andCommon Fibular) |
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Cervical Plexus (C1 - C5) |
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- the Phrenic Nerve (C3 - C5) which innervates theDiaphragm |
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Brachial Plexus (C5 - T1) |
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- supplies innervation to the shoulder and upper limb |
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- supplies part of the abdominal walls, externalgenitalia, and part of the proximal lower limb |
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- supplies innervation to the lower limb |
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Sciatic Nerve (L4 - S3) = |
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largest nerve in the bodywhich is made up of two separate nerves (Tibial andCommon Fibular) |
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Sciatic Nerve (L4 - S3) = |
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largest nerve in the bodywhich is made up of two separate nerves (Tibial andCommon Fibular) |
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inflammation of the Sciatic Nerve - pain may follow the nerve all the way down thefoot |
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- ventral rami - innervate the intercostal spaces |
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- the area of the skin that provides sensory input through onepair of spinal nerves or Cranial nerve 5 |
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Shingles "Singles with Shingles" |
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- an infection caused by the Herpes Zoster virus - this virus also causes Chicken Pox - this virus remains dormant in the Dorsal Root Ganglion - can cause skin eruptions along the infected nerve - lesions are acutely painful |
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- caused by the Poliovirus - causes fever, severe headaches and muscle aches, weakness - can cause paralysis - virus can destroy motor neuron cell bodys in the AnteriorHorn - death associated with Respiratory or Heart failure - the virus is often transmitted by fecal-oral contamination(and Yeah its just what you think!) |
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- inflammation of one or more nerves - causes pain along the pathway of the involved nerves - ex. Sciatica = neuritis of the Sciatic nerve |
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Amyotrophic Lateral Sclerosis (ALS) |
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- "Lou Gehrig's Disease" - disease that effect nerve cell bodies in the Anterior Hornand Brain (i.e. motor neurons) - leads to progressive muscle degeneration - person often retains most of their sensory stimulus - often begins in mid-life - a chronic, progressive disease |
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