Shared Flashcard Set

Details

Chapter 15 Test
Studying and Manipulating Genomes
40
Biology
9th Grade
04/20/2009

Additional Biology Flashcards

 


 

Cards

Term
In 1953, who unveiled their model of the DNA double helix and ignited a global blaze of optimism about genetic research?
Definition
James Watson and Francis Crick
Term
In 1972, who was the first to made recombinant DNA?
Definition
Paul Berg
Term
In 1977, who developed a method for determining the nucleotide sequence of cloned DNA fragments?
Definition
Allan Maxam, Walter Gilbert, Fred Sanger
Term
What is all the DNA in a haploid number of chromosomes?
Definition
Genome
Term
In what year did several independent organizations launch their own versions of the Human Genome Project?
Definition
1987
Term
Who started a human genome company and declared that their company would not only sequence the human genome, it would also patent the genome?
Definition
Walter Gilbert
Term
In early 1988, the NIH effectively annexed the entire Human Genome Project by hiring who has its head and providing researchers with 200 million dollars per year?
Definition
James Watson
Term
After Watson resigned in 1992 because of a disagreement with the NIH about patenting partial gene sequences who replaced him in 1993?
Definition
Francis Collins
Term
Who started Celera Genomics in 1998?
Definition
Craig Venter
Term
When was sequencing of the human genome officially completed?
Definition
2003- 50 years after the discovery of DNA structure
Term
What is a DNA molecule that contains genetic material from more than one organism?
Definition
Recombinant DNA
Term
What percent of the coding regions in human DNA have been deciphered with a high degree of accuracy?
Definition
99%
Term
In 1970 who studied the viral infection of Haemophilus influenzae and isolated the first restriction enzyme?
Definition
Hamilton Smith
Term
What is a protein that recognizes and cuts specific sequences of nucleotides in double-stranded DNA?
Definition
Restriction enzyme
Term
What repairs enzymes that join breaks in DNA molecules; connects new DNA fragments during replication?
Definition
DNA ligase
Term
What is a small circle of extra DNA with just a few genes?
Definition
Plasmid
Term
What is a modified plasmid that accepts foreign DNA and slips into a host bacteria, yeast, or some other cell?
Definition
Cloning vector
Term
What does chromosomal DNA usually contain?
Definition
Introns
Term
What is a viral enzyme that uses the mRNA as a template?
Definition
Reverse transcriptase
Term
What is a collection of bacterial cells that house different cloned fragments of DNA?
Definition
Gene library
Term
What are the cloned fragments of an entire genome?
Definition
Genomic library
Term
What is derived from mRNA?
Definition
cDNA
Term
What is a short stretch of DNA labeled with a radioisotope (or sometimes a pigment), may be used to find a one-in-a-million clone?
Definition
Probe
Term
What is base-pairing between DNA (or RNA) from more than one source?
Definition
Nucleic acid hybridization
Term
What is a short stretch of nucleotides?
Definition
Oligomer
Term
What is a method that rapidly amplifies the number of specific DNA fragments?
Definition
PCR (Polymerase Chain Reaction)
Term
What are synthetic nucleotide oligomers, usually between ten and thirty bases long?
Definition
Primers
Term
What is a unique array of DNA sequences inherited in a Mendelian pattern from parents?
Definition
DNA fingerprint
Term
More than what percent of DNA is the same in all humans?
Definition
99%
Term
What are many copies of the same short DNA sequences, positioned one after the other along the length of a chromosome?
Definition
Tandem repeats
Term
What is it called when molecules that migrate through a gel matrix in response to an electric force become separated by size and charge?
Definition
Gel electrophoresis
Term
How many innocent people have been freed due to DNA fingerprinting?
Definition
143
Term
What is a robotic method of determining the nucleotide sequence of a region of DNA?
Definition
Automated DNA sequencing
Term
What is the process of changing the genetic makeup of an organism, often with intent to alter one or more aspects of phenotype?
Definition
Genetic engineering
Term
What is an organism into which DNA from another species has been inserted?
Definition
Transgenic
Term
What is transferring an organ from one species to another?
Definition
Xenotransplantation
Term
What is the study of genes and gene function in humans and other organisms?
Definition
Genomics
Term
Which branch of genomics deals with the actual mapping and sequencing of genomes of individuals?
Definition
Structural
Term
Which branch of genomics deals with finding evolutionary relationships among groups of organisms?
Definition
Comparative
Term
What is the transfer of one or more normal or modified genes into a person's body cells to correct a genetic defect or boost resistance to disease?
Definition
Human Gene Therapy
Supporting users have an ad free experience!