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Chapter 15
The Chromosomal Basis of Inheritance
25
Biology
Not Applicable
05/06/2005

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Term
chromosome theory of inheritance
Definition
genes have specific loci on their chromosomes and it is the chromosomes that undergo segregation and independant assortment
Term
wild type
Definition
phenotype most common in natural populations
Term
mutant phenotypes
Definition
mutated wild-type alleles
Term
sex-linked genes
Definition
genes located on a sex chromosome
Term
linked genes
Definition
genes located on the same chromosome that are inherited together in a genetic cross
Term
genetic recombination
Definition
production of offspring with new combinations of traits inherited from two parents
Term
parental types
Definition
offspring that inherits a phenotype matching one of the parental phenotypes
Term
recombinants
Definition
offspring that have different combinations of seed shape and color than either parent
Term
genetic map
Definition
ordered list of the genetic loci along a particular chromosome
Term
linkage map
Definition
genetic map based on recombination frequencies
Term
cytological maps
Definition
locate genes with respect to chromosomal features
Term
Duchenne muscular dystrophy
Definition
disease that causes progressive weakening of the muscles and loss of coordination
Term
hemophilia
Definition
excessive bleeding; absence of blood clotting protein
Term
Barr Body
Definition
compact object that is the condensed form of the inactive X in each cell of a female
Term
nondisjunction
Definition
members of a pair of homologous chromosomes do not move apart properly during Meiosis I or in which sister chromatids fail to separate during meiosis II
Term
aneuploidy
Definition
abnormal chromosome number
Term
trisomic
Definition
condition of having three copies of a given chromosome in each somatic cell rather than the normal number of two
Term
monosomic
Definition
chromosome having no homologue, especially an unpaired X-chromosome
Term
polyploidy
Definition
Having one or more extra sets of chromosomes
Term
duplication
Definition
copy
Term
inversion
Definition
chromosomal defect in which a segment of the chromosome breaks off and reattaches in the reverse direction
Term
translocation
Definition
rearrangement of chromosomal structure
Term
down syndrome
Definition
congenital disorder, caused by the presence of an extra 21st chromosome, in which the affected person has mild to moderate mental retardation, short stature, and a flattened facial profile
Term
genomic imprinting
Definition
parental effect on gene expression
Term
fagile X Syndrome
Definition
inherited disorder caused by a defective gene on the X-chromosome and causing mental retardation, enlarged testes, and facial abnormalities in males and mild or no effects in heterozygous females
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