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Chapter 20
Lymphatic System
78
Anatomy
Undergraduate 2
02/18/2010

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Term
What are the three main parts of the lymphatic system
Definition
A network of lymphatic vessels called lymphatics
Lymph
Lymph Nodes
Term
What is the main function of the lymphatic system
Definition
to return interstitial fluid and leaked plasma proteins back to the blood.
Term
Once interstitial fluid enters lymphatics it is known as
Definition
lymph
Term
Lyphoid organs and tissues provide the structural basis for
Definition
immune system
Term
What is a function of the lymphatic system that is involved with the digestive tract
Definition
Fat absorbtion from the digestive tract, LACTEALS
Term
What direction does lymph flow
Definition
toward the heart
Term
What are 3 different lymph vessels
Definition
Lymphatic capillaries
Lymphatic collecting vessels
Lymphatic trucks and ducts
Term
Lymphatic capillaries are similar to blood capillaries except
Definition
they are very permeable (take up cell depris, pathogens, and cancer cells)
and
Endothelial cells overlap to form one way minivalves. They are anchored by collagen filaments, preventing collapse of capillaries.
Term
Where are Lymphatic capillaries not found
Definition
Bones, teeth, bone marrow, and CNS
Term
What are lacteals
Definition
Specialized lymph capillaries present in intestinal mucosa
Term
What is the functin of lacteals
Definition
absorb digestied fat and deliver fatty lymph called CHYLE to the blood.
Term
Lymphatic collecting vessels are similar to veins except
Definition
they have thinner walls, more internal valves and Anastomose more frequently
Term
Collecting vessles in the skin travel with_______
Deep collecting vessels travel with ________
Definition
Term
How are nutrients suppplied to the lymphatic connecting vessels?
Definition
Vasa Vasorum
Term
What are lymphatic trunks formed by?
Definition
the union of the largest collecting ducts
Term
What are the two ducts in which lymph can be delivered?
Definition
Right lymphatic duct
Thoracic duct
Term
What does the right lymphatic duct drain?
Definition
the upper right upper arm and the right side of the head and thorax
Term
What does the thoracic ducts arise from?
What do they drain?
Definition
Arise from cisterna chyli
Drane the rest of the body.
Term
Where is lymph emptied into?
Definition
Venous circulation via the junction of the inter jugular and subclavian veins
Throacic left
Right duct Right
Term
How is lymph propelled?
Definition
Pulsations of nearby arteries
COntraction of smooth muscle in the walls of the lymphatics.
Term
What are the main warriors of the immune system
Definition
T Lymphocytes
B Lymphocytes
Term
What is the function of T Cells
Definition
Manage the immune response
Destroy foreign cells
Term
What is the function of Bcells
Definition
Produce plasma cells which in turn secrete antibodies
Term
What are antigens
Definition
Anything the body perceives as foreign
Term
What do macrophages do
Definition
phagocytize foreign substances and help activate T cells
Term
What do dendritic cells do
Definition
capture antigens and deliver them to lymph nodes
Term
What do reticulocytes do
Definition
Produce stroma that supports other cells in lyphoid organs examination
Term
What are the two types of lymphoid tissue
Definition
Diffuse Lyphatic tissue
Lymphatic follicles
Term
What is the function of lymphoid tissue
Definition
Houses and provides a proliferation site for lymphocytes
Furnishes a surveillance vantage point
Term
Diffuse lymphatic tissue comprises _________ _________ __________ elements in every body organ
Definition
scattered reticular tissue
Term
Where are there large collections of diffuse lymphatic tissue fouund
Definition
Lamina propria of mucous membranes and lymphoid organs
Term
WHat are lymphatic follicles
Definition
Nodules solid spherical bodies of tightly packed reticular elements and cells
Term
What is a germinal center composed of
What is it part of
Definition
dendritic and B cells
Lymphatic follicles
Term
What are lymph Nodes
Definition
Principal Lymphoid organs of the body
Term
Where are lymph nodes embedded?
Definition
in connective tissue, in clussters along lymphatic vessels.
Near the body surface in inguinal, axillary, and cervical regions of the body
Term
What are the functions of lymph nodes
Definition
Filter lymph-macrophages destroy mircroorganisms and debris
Immune system-lymphocytes are activated and moint an attack against antigens
Term
What is the shape of a lymph node
Definition
Bean shaped
Term
What are two histologically distinct regions of a lymph node
Definition
Cortex and Medulla
Term
What extend inward and divide lymph nodes into compartments
Definition
Trabeculae
Term
What does the cortex of a lymph node contain
Definition
Fillicles with germinal centers, heavy with dividing B Cells
Term
What do dendritic cells do?
Definition
Nearly encapsulate the follicles and present antigens to tcells and bcells
Term
What does the Deep cortex house
Definition
T cells in transit
Term
Where do t cells circulate
Definition
They circulate continuously among the blood, lymph nodes, and lymphatic stream
Term
What extend inward from the cortex and contain b cells and t cells and plasma cells
Definition
Medullary cords
Term
Lymph Sinuses contain
Definition
Macrophages
Term
What does afferent mean
Definition
Entering
Term
Where does lymph exit lymph nodes
Definition
at the hilus via efferent vessels
Term
What does the fact that there are only a few efferent efferent vessles do to the lymph flow
Definition
Fewer efferent vessels cause flow of lymph to stagnate which allows lymphocytes and macrophages to carry out functions.
Term
What are 4 other lymphoid organs
Definition
Spleen, Thymus gland, tonsils, and peyers patches
Term
What are lymphoid organs composed of
Function?
Definition
Reticular connective tissue
Help protect the body.
Term
What is the only thing that filters lymph?
Definition
Lymph Nodes
Term
What is the largest lymphoid organ
Definition
Spleen
Term
What are the functions of the spleen
Definition
Site of lymphocyte proliferation and immune surveillance and response
Cleanses blood of aged cells and platelets and debris
Term
What does the spleen store
Definition
Break down products of RBCs
Blood Platelets
Term
where does fetal erythrocyte production occur
Definition
Spleen
Term
What phagocytes does the spleen contain
Definition
lymphocytes, macrophages, and huge number of erythrocytes
Term
What are two distinct areas of the spleen
Definition
What pulp and Red pulp
Term
Where is white pulp loc, func, and comp
Definition
loc: Around central arteries
funct: involved in immune function
Comp:Mostly lymphocytes on retuclar fibers
Term
Red pulp loc, func, and comp
Definition
located: in venous sinuses and splenic cords
Comp:rich in macrophates for disposal of worn out RBCs and blood born pathogens.
Term
When does the thymus stop growing
Definition
during adolescence then begins to atrophy
Term
What do thymic lobes contain
Definition
Outer cortex and inner medulla
Term
What does the cortex of a thymic lobe contain
Definition
densly packed lymphocytes and scattered macrophates
Term
What does the medulla of a thymic lobe contain
Definition
fewer lymphocytes and thymic corpuscles
Term
what are corpuscles involved in
Definition
regulatory T cell development
Term
In what ways does the thymus differ from other lymphoid organs
Definition
It functions strictly in T lymphocyte maturation
It does not directly fight antigens
The stoma have star shaped epithelial cells not reticular fibers
Term
________ provide the environment in which T lymphocytes become immunocompetent.
Definition
Thymocytes
Term
What is the siplist lymphoid organs
Definition
tonsils
Term
What do the tonsils form a ring aroudn?
Definition
The pharynx
Term
What are 4 different tonsils
Definition
Palatine-back of mouth
Lingual-base of tongue
Pharyngeal-posterior wall of nasopharynx
Tubal-surrounding the oppenings of the auditory tubes ito the pharynx
Term
Tonsils contain follicles with
Definition
Germinal centers
Term
Crypts of tonsils do what
Definition
trap and destroy bacteria and particulate matter
Term
What are peyer's patches
Definition
Clusters of lymphoid follicles
Term
Where are peyers patches found
Definition
in the wall of the distal portion of the small intestine and in the appendix
Term
Peyers patches in the appendix function
Definition
destroy bacteria, preventing them from breaching intestinal wall,
Generate memory lymphocytes
Term
What does MALT stand for
Definition
Mucosa associated lymphatic tissue
Term
What are the peyers patches, tonsils, and the appendix associated with
Definition
MALT the digestive tract
Term
What are lymphoid nodules associated with
Definition
in the walls of the bronchi
Respiratory tract
Term
Function of MALT
Definition
Protects the digestive and respiratory systems from foreign matter
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