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Chapter 20: The Cardiovascular System
Blood
37
Anatomy
Undergraduate 1
12/10/2011

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Term
What kind of tissue is blood?
Definition
specialized fluid connective tissue
Term
What are the 3 functions of blood?
Definition
  1. distributes nutrients, oxygen, and hormones
  2. carries metabolic wastes to the kidneys for excretion
  3. transports specialized cells that defend peripheral tissues from infection and diseases-immune system conduct
Term
What are the 2 components of blood?
Definition
  • plasma 55% the liquid matrix of blood
    • 92% water
    • dissolved proteins
  • formed elements
    • red blood cells
    • white blood cells
    • platelets
Term
What is the function of RBCs?
Definition
transport oxygen and carbon dioxide
Term
What is the function of WBCs?
Definition
components of the immune system
Term
What is the function of platelets?
Definition
essential for blood clotting
Term
What are the 3 major classes of plasma proteins?
Definition
  • albunins
  • globulins
  • fibrinogen
Term
albumins
Definition
  • 60% of plasma proteins
  • transport of fatty acids, steroid hormones, cations, biliruben, and drugs and other substances
  • smallest of plasma proteins
  • regulates colloidal osmotic pressure
Term
globulins
Definition
  • approximately 35% of plasma proteins
  • antibodies
  • immunoglobulins/transport globulins
Term
immunoglobulins
Definition

ANTIBODIES

attach foreign pathogens and proteins

Term
fibrinogen
Definition
  • 4 percent of plasma proteins
  • basic framework for blood clot
    • clot reaction: platelets bound together by fibrinogen
  • largest of the plasma proteins
Term
erythrocytes
Definition
red blood cells
Term
Red blood cells
Definition
  • 45% of blood volume
  • transport oxygen and CO2 in bloodstream
  • concave in shape
    • greater surface area for gas transport, makes it flexible for squeezing through capillaries
  • 120 day life span
  • no nucleus or organelles
Term
hematocrit
Definition

value indicates the percentage of whole blood minus the plasma

NORMAL FOR MEN: approx 46

NORMAL FOR WOMEN: approx 42

Term
hemoglobin
Definition
  • hemoglobin molecules account for more than 95% of the erythrocytes proteins
  • transport oxygen and carbon dioxide
  • red pigment
  • oxygenated hemoglobin is bright red
  • deoxygenated hemoglobin has a deep red color
Term
What are the 4 blood types and what antigens does each have?
Definition

Type A: has antigen A

Type B: has antigen B

Type AB: has both

Type O: has neither

Term
leukocytes
Definition
white blood cells
Term
What is the function of white blood cells?
Definition
  • immune defense
  • remove toxins & wastes & abnormal or damaged cells
Term
white blood cells
Definition
  • larger than RBC
  • very short life span
  • cross tunica areas of vessels into tissues
Term
extravasation
Definition
when white blood cells move from capillaries into tissues
Term
What are the 2 major classes of WBCs?
Definition
  1. granular leukocytes (granulocytes)
  2. agranular leukocytes (agranulocytes)
Term

What are the 3 tyoes of granulocytes?

"Nice Eyes Baby"

Definition
  • neutrophils 50-70%
  • eosinophils 2-4%
  • basophils 1%
Term
neutrophils
Definition
  • phagocytosis specialists
  • chemical release after death
Term
Eosinophils
Definition
  • release enzymes to reduce inflammation
  • cytoxic to parasites
Term
basophils
Definition
  • release histamine
  • increase permeability
Term
What are the 2 types of agranular leukocytes?
Definition
  • monocytes
  • lymphocytes
Term
monocyte
Definition
  • largest WBC
  • account for 2-8 percent of the wbc population
Term
lymphocytes
Definition
  • usually slightly larger than RBCs
  • acount for 20-30 percent of the WBC population
Term
What are the 3 types of lymphocytes?
Definition
  1. T cells
  2. B cells
  3. NK cells
Term
T cells
Definition
enter peripheral tissues and attack foreign cells directly
Term
B cells
Definition
differentiate into plasma cells that secrete antibodies that attack foreign cells or proteins in distant portions of the body
Term
NK cells
Definition
immune surveillance, destruction of abnormal tissue cells; important in preventing cancer
Term
hemopoiesis
Definition
the process of blood cell formation
Term
erythropoiesis
Definition
formation of erythrocytes
Term
myeloid tissue
Definition

RED BONE MARROW

the primary site of blood cell formation in the adult

Term
leukopoiesis
Definition
production of white blood cells
Term
blood doping
Definition
  • boosting number of red blood cells
  • boost hematocrit for 6 to 24 weeks
  • side effects
    • abnormally high RBCs
    • high viscous blood
    • strain heart/heart failure
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