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Chapter 3
Chapter 3
48
Anatomy
Undergraduate 1
02/17/2012

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Term
Cell
Definition
  • All living things are made up of it
  • It is basic unit of life

 

 

There are three major parts

  1. Plasma membrane
  2. Cytoplasm
  3. Nucleus
Term
Plasma membrane
Definition

- It surround the cell and has three major functions

  • It isolates ans protects the cell from external environment
  • It regulated the movement of substances into and out of the cell
  • It contain receptor protein that allow cells to recognize, interact, and communicate with one another.

 

Term
Selectively permeable
Definition
it allow or prevent the certain substance to enter and leave the cell
Term
Cytoplasm
Definition

It is the fluid-filled area inside plasma membrane and mainly consist of water.

It may contain many type of organelles

Term
Nucleus
Definition
it is the control center of the cell and it contain the genetic material DNA that regulate all the cells activities and processes
Term
Fluid Mosaic Model
Definition
the structure of plama membrane was describe by S.J. Singer and G.L.Nicolson in 1972 it refered ________
Term
Components of plasma membrane
Definition

It consists of phospholipid, protein, cholesterol

 

Phospholipid arranged in a double layer of parallel rows that referred to as phospholipid bilayer

Cholesterol molecule stabilized the membrane by bonding some of the fatty acids, prevent them from clumping and allowing for fluid moment of the membrane

Protein are embeded in the phospholipid bilayer of the membrane and are constantly moving and forming changing mosaic pattern

Term
There are two proteins that associated with the plasma membrane
Definition

Integral proteins - extend part of the way or all the way through the membrane and protrude( extend past the phospholipid) in both sides

 

Peripheral proteins- they are attached to the integral protein and protrude either side of the membrane. They function as receptor protein which allow response to internal and external stimuli and communication and interaction between cells

 

Term
transmembrane proteins
Definition
Integral proteins extend all the way through the membrane are specifically called _____
Term
Channel proteins
Definition
transmembrane may form clusters producing passageway and channel through the memrane which allow for the transport of substance through th membrane. These clusters of transmembrane protein are specifically called _________.
Term
Glycoprotein
Definition
Lipid and carbohydrate may be attached to the peripheral protein on the outer surface of the plasma membrane , respectively forming lipoprotein and ____________
Term
Glycocalyx
Definition

"sugar coat"

 

the glycoprotein form a covering on the outer surface of the plasma membrane are called_____

 

Serve as bonding site for bacteria, virus, toxins, and some cancer cell, which allow for the defense mechanism of the body to become activated and destroy them

Term
Microvilli
Definition

Some cells have small, finger-liked projection of the outer surface of the plasma membrane

 

Increase the surface area for absorption of substances from the external environment. They are mainly found in stomach, intestines, and kidneys.

Term
Two major processes involved in membrane transport
Definition

1) Passive processes:substances move an area of higher concertration to an area of lower concentration along a concentration gradient and enery is not require from the cell

2) Active processes: substances move an area of lower concentration to an area higher concentration agaist a concetration gradient and energy is require from the cell in the form of ATP

Term
Passive processes
Definition

the smaller the particle, the greater the concentration, the higher the temperature, the faster the movement

 

there are four major type

  1. simple diffusion
  2. osmosis
  3. facilitated diffusion
  4. filtration
Term
simple diffusion
Definition
is the movement of atoms, ions, and molecules from and an area of higer concentration to lower concentration along a concentration gradient without the use of energy
Term
osmosis
Definition

the diffusion of water from and area of higer concentration to lower concentration through the membrane. Water is dissoved substance and solute which also move through membrane as a much lower rate than water.

The movement of solute is referred to as dialysis

There are three osmotic conditions

isotonic, hypotonic,hypertonic

 

Term
isotonic
Definition
the concentration of water and the concentration of solute are equal inside and outside of the cell. Water enter and leave the cell at and equal rate.
Term
hypotonic
Definition
The concentration of water is higher and the concentration of solute is lower outside of the cell than inside of the cell. Wate move from the higer concentration outside the cell to the lower inside of the cell. The cell will swell,becom turgid, it may lyse
Term
hypertonic
Definition
the concentration of water is higher and the concentration solute is lower inside of the cell than outside of the cell. Water move out from higer concentration inside of the cell to lower concentration outside of the cell.Water will shrink, shrivel, or crenate
Term
facilitated diffusion
Definition
the specific substance move from an area of higher concentration to an are of lower concentration through passageway in the plasma membrane formed by channel protein with the aid of carrier and transport protein
Term
filtration
Definition
is the movement of water and solute from an area of higher pressure to an area of lower pressure through membrane or vessel wall(blood and lymphatic). Fluids are  forced through membrane and vessel wall by a force known as hydrostatic pressure.
Term

Two major types of active processes

 

Definition

1.Active transport:substance that move from an area of lower concentration to an area of higher concentration through passageway in the plasma membrane formed by channel protein and with the aid of transport protein and ATP. Transport protein is ready pick up more of the substance and ATP and transport it across the membrane


2. Bulk transport: large solid particles or liquid droplets are moved into and out of the cell and ATP is required. Large solid particles and liquid are surrounded by a memrane and the structure is referred to as vesicle.


There are two bulk transort

Exocytosis and edoxytosis

Term
Exocytosis
Definition

"out of the cell"

within the cell the large solid particle or liquid droplets are packed in vesicle and the vesicle move through the cytoplasm to the plasma membrane. The membrane of the vesicle fused with the plasma membrane and the contents of the vesicle are released to the outside of the cell.

Term
endocytosis
Definition

"into the cell"

large solid particle or liquid droplet are packed in vesicle and move into the cell and ATP is require.

 

There are three types

  1. pinocytosis
  2. phagocytosis
  3. receptor-mediated endocytosis
Term
pinocytosis
Definition

"cell drinking"

when the liquid droplets come into contact with outer surface of plasma membrane, a deprenssion forms in the membrane. The membrane fold inward and eventually surround the liquid droplet. The plasma membrane pinches off as a vesicle

Term
phagocytosis
Definition

"cell eating"

When large solid particles come into contact with outer surface of the plasma membrane, the membrane is stimulated to project outward and surround the particle. The membrane then pulls inward and pinches off as a vesicle.

Term
receptor-mediated endocytosis
Definition

specific substance bond with the protein receptor on the outer surface of the plasma membrane. As the substance accumulate, a depression form in the membrane.

 

On the cytoplasm side of membrane of the depression, bristle-like protein called clathrin, and the depression is referred to as coated pit. The membrane pinches off as a coated vesicle

Term
maintains a fairly constant surface are of the plasma membrane
Definition
Endocytosis and exocytosis work together so that the surface area of plasma membrane remain fairly constant.
Term
Intercellular contacts
Definition

cell interact and communicate through _______

 

There are three type

  1. tight junctions
  2. desmosomes
  3. gap junctions

 

Term
tight junctions
Definition

"leakproofing"

protein molecule of adjacent cell fuse together along a series of ridges, like a zipper, forming an impermeable barrier. Substance such as digestive enzyme and bacteria in the ingestines prevented entering bloodstream.

Term
desmosome
Definition

"cell to cell adhesion"

animal tissue stretch, compress, and bend as organism moves. Cell must adhere to each other or they would seperate.

Term
Gap junction
Definition

"cell to cell communication"

Channel protein of adjacent cell fuse together to form a continuous passageways between two cells which through nutrients and substance are exchanged.

Term
ribosomes
Definition
they consist RNA and protein and are formed in the nucleus. They function in protein synthesis and are found floating freely in the cytoplasm and attached to the rough endoplasmic reticulum
Term
endoplasmic reticulum (ER)
Definition

It is continuous with the nucleus membrane and form a serious of membrane surrounded the channel for intracellular transport of substances.

 

 

 

 

 

There are two type of ER

rough ER

smooth ER

Term
rough ER
Definition
it contain ribosome on outer surface and function in the manufacture and transport of protein
Term
smooth ER
Definition
lacks ribosomes on outer surface and function in manufacture and tranport of steroids and other lipids and in detoxifying drugs and other chemicals
Term
Golgi complex and apparatus
Definition
It is continuous with endoplasmic reticulum (ER) and it consist of membrane-surrounded flattened sacs. It modifies, compacks, stores and transport substances from rough and smooth ER. It aslo manufacture lysosome.
Term
Lysosome
Definition
They are membrane-surrounded sacs which contain powerful digestive enzyme(hydrolytic enzyme) and they funtions in intracellular digestion. It also function as "suicide bags" that destroy injured and dying cells
Term
Peroxisome.
Definition
They are membrane-surrounded sacs which contain enzyme catalase. Catalase break down hydrogen peroxide into water and oxygen
Term
mitochondria
Definition
they are surround by a double membrane and function in producing energy known as ATP. They referred to as powerhouse of the cell
Term
Cytoskeleton
Definition

It consist of protein and function in structural support, movement of substances, and movement of cells

 

 

 

There are three type of____

1. microfilament
2. intermediated filament
3. microtubules

Term
Microfilaments
Definition
They are made up of protein actin and misosin and function in contraction and relaxation of muscle fiber
Term
Intermediate filaments
Definition
It consist various type of protein and function in cell support , movement of substance, and organelles within the cells
Term
Microtubules
Definition

They consist of tubulin protein and function in structural support , cell movement, and movement of substance

 

 

There are three structures composed of ____

1.Centrioles:they function in forming support structure for chromosomes during cell devision known as mitosis

2.Cilia:they are short, hairlike struture on the surface of some cell and they function in moving substances across the cell

3.flagella:they are long whipelike structure and function in moving a cell

Term
nucleus
Definition

is surrounded by a double membrane and function as a control center of the cell

 

 

 

it contain two major structure

  1. nucleolus
  2. chromotin and chromosome
Term
nucleolus
Definition
It consists of RNA and protein and function in the synthesisof ribosome
Term
Chromotin and chromosome
Definition

When a cell is not diving, DNA and protein form a thin threadlike structure called_____

 

When a cell is dividing, chromatin shorten, thicken, coil, and condense become known as  ________

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