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Chapter 3
Essentials of Human Anatomy and Physiology; 10th edition by Marieb
101
Anatomy
Undergraduate 1
06/18/2015

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Term
Cells
Definition
The structural units of all living things
Term
Cell Theory
Definition
1. Basic structural/functional unit of organisms
2. Activity of organism depends on cell activity
3. Principle of complementarity
4. Continuity of life has a cellular basis
Term
Principle of Complementarity
Definition
Biochemical activity of cells are dictated by the relative number of their specific subcellular structures
Term
Interstitial fluid
Definition
A dilute saltwater solution derived from the blood that bathes the cells of the human body
Term
Generalized cell
Definition
Describes functions that are common to all cells
Term
Cell Nucleus
Definition
The control center of the cell; contains the genes
Term
Cytoplasm
Definition
Semi-fluid cellular material outside the nucleus and inside the plasma membrane
Term
Plasma Membrane
Definition
Transparent barrier that contains the cell contents and separates them from the surrounding environment; selectively permeable
Term
Nuclear envelope
Definition
Double-membrane barrier that surrounds the nucleus
Term
Nucleoli
Definition
Small bodies within the nucleus where ribosomes are assembled
Term
Chromatin
Definition
Loose threads of DNA that are intertwined with protiens (condense into chromosomes when cell dividing)
Term
Nuclear pores
Definition
Points at which the two layers of the nuclear envelope fuse-allows substances to pass through
Term
Nucleoplasm
Definition
Jelly-like fluid in which nuclear elements are suspended
Term
Fluid Mosaic Model
Definition
P.M. composed of phosopholipid bilayer, proteins, and cholesterol
Term
Hydrophobic vs. Hydrophilic
Definition
Water-fearing vs. Water-loving (reason for phospholipid bilayer organization)
Term
Protein functions (membranes)
Definition
Pores (passive) and Carriers (active)
Term
Tight Junctions
Definition
Impermeable; adjacent plasma membranes are fused together to prevent substances from passing through
Term
Desmosomes
Definition
Anchoring junctions; thickening of membranes that are connected by protein filaments (extend into cell like guy wires)
Term
Gap Junctions
Definition
Allow communication via connexons
Term
Glycoproteins
Definition
Proteins with attached sugar groups that reside in the plasma membrane
Term
Glycocalyx
Definition
The sugar-rich surface area of the plasma membrane
Term
Connexon
Definition
Hollow cylinders composed of proteins that allow for communication in gap junctions
Term
Cytosol
Definition
semi-transparent fluid that suspends the elements of the cytoplasm
Term
Inclusions
Definition
Chemical substances (not present in all cells) usually stored nutrients or cell products (Ex: pigments, lipids etc)
Term
Organelles
Definition
Specialized compartments that provide the metabolic machinery of the cell
Term
Mitochondria
Definition
Provides energy for the cell/produces ATP; Cristae-protrusions of inner membrane
Term
Ribosomes
Definition
Made of proteins and ribosomal RNA; sites of protein synthesis (studded on rough ER)
Term
Endoplasmic reticulum
Definition
Provides network for proteins to travel through the cell; rough ER-membrane factory, smooth ER-lipid metabolism/detox
Term
Golgi apparatus
Definition
Modify and package cellular proteins (for secretion, membranes, or lysosomes)
Term
Lysosomes
Definition
Contain digestive enzymes that break-down non-usable cell structures/foreign substances
Term
Peroxisomes
Definition
Contain oxidase enzymes that detoxify harmful substances/disarm free radicals
Term
Vesicles
Definition
Protrusions of membranes that surround substances for transport (same) or secretion (secretory)
Term
Free radicals
Definition
Reactive chemicals with unpaired electrons that scramble proteins/nucleic acids
Term
Cytoskeleton
Definition
Network of protein structures that extends throughout the cytoplasm
Term
Intermediate filaments (Cy.Sk.)
Definition
Strong, stable, ropelike-form desmosomes and provide internal guy wires
Term
Microfilaments (Cy.Sk.)
Definition
Involved in cell motility and produce changes in cell shape
Term
Microtubules (Cy.Sk.)
Definition
Determine overall shape of cell and distribution of organelles
Term
Centrioles
Definition
Generate microtubules and direct the formation of mitotic spindle in cell division
Term
Cilia
Definition
Project from cell surface; Move substances along cell surface
Term
Flagella
Definition
Longer cilia, propels the cell itself (only present on sperm cells)
Term
Microvilli
Definition
Increase cells surface area, which aids in absorption
Term
Fibroblast
Definition
Elongated cell that secretes cable-like fibers, connects body parts
Term
Erythrocyte
Definition
Red blood cell; carries O2 in blood, has no organelles
Term
Epithelial cell
Definition
Hexagonal, has many intermediate filaments that resist tearing, covers/lines organs
Term
Skeletal/Smooth muscle cells
Definition
Filled with contractile filaments; Moves organs/body parts
Term
Fat cell
Definition
Spherical, contains large lipid droplet-Stores nutrients
Term
Macrophage
Definition
Phagocytic cell; extends pseudopods and crawls through tissue to fight disease
Term
Nerve cell/Neuron
Definition
Has long processes/extensions; Stores information and controls body functions
Term
Oocyte
Definition
Female egg cell, Largest cell in body used in reproduction
Term
Sperm
Definition
Male, contains flagellum to help reach egg-used in reproduction
Term
Solution
Definition
Homogeneous mixture of two or more components
Term
Solvent
Definition
Dissolving medium; Substance within a mixture that is present in the largest amount
Term
Solutes
Definition
Dissolved substances; present in smaller amounts in solutions
Term
Intracellular fluid
Definition
Nucleoplasm and cytosol; solution of gases, nutrients, and salts in water
Term
Interstitial fluid
Definition
Fluid that bathes the exterior of cells; solution of gases, nutrients, and salts in water
Term
Diffusion
Definition
Passive transport; process by which molecules and ions move from areas of higher concentration to lower concentration
Term
Filtration
Definition
Passive transport; solutions are forced through membrane/capillary wall by hydrostatic pressure
Term
Osmosis
Definition
Diffusion of water through a selectively permeable membrane
Term
Aquaporins
Definition
Special pores within the plasma membrane that allow osmosis to occur
Term
Facilitated diffusion
Definition
Carrier and Channel mediated diffusion
Term
Active transport
Definition
Protein carriers combine specifically to certain substances-requires ATP to energize solute pumps against concentration gradient
Term
Carrier-mediated Diffusion
Definition
Protein carrier for specific chemical changes shape at presence of substrate; driven by kinetic energy
Term
Channel-mediated Diffusion
Definition
Items pass through open channels in cell membrane; mostly ions
Term
Sodium-potassium pump
Definition
Carries Na+ out and K+ into cell; used in neuron firing
Term
Exocytosis
Definition
Vesicular transport; process of cell secretion of substances
Term
Endocytosis
Definition
Vesicular transport; process by which cells engulf substances and transport them into cells
Term
Phagocytosis
Definition
Process by which cells engulf substances using pseudopods
Term
Pinocytosis
Definition
Process by which cells engulf extracellular fluid
Term
Receptor-mediated endocytosis
Definition
Mechanism for taking up targeted molecules via plasma membrane receptor proteins
Term
Interphase
Definition
Period of the cell life cycle in which the cell grows and carries on metabolic activites
Term
Mitosis
Definition
Process by which a cell's nucleus is divided
Term
Cytokinesis
Definition
Process by which a cell's cytoplasm is divided-begins during anaphase and completes during telophase
Term
Prophase
Definition
First phase of cell division in which centrioles begin to move and form mitotic spindles
Term
Metaphase
Definition
Second phase of cell division; Chromosomes line up at metaphase plate
Term
Anaphase
Definition
Third phase of cell division; Chromatids split into chromosomes
Term
Telophase
Definition
Fourth phase of cell division; Chromosomes become chromatin
Term
Cleavage Furrow
Definition
Contractile ring made of microfilaments that forms during cytokineses-pinches cytoplasm into two
Term
Gene
Definition
A DNA segment that carries the information for building one protein/polypeptide chain
Term
Transcription
Definition
Transfer of info from DNA into complementary base sequence of mRNA
Term
Translation
Definition
Info carried in mRNA is decoded into an amino acid sequence
Term
Triplet
Definition
Three-base sequence on DNA strand specifying an amino acid
Term
Codon
Definition
Three-base sequence on mRNA strand specifying an amino acid
Term
Primary tissue types
Definition
Epithelium, connective tissue, nervous tissue, muscle
Term
Epithelium
Definition
Lining, covering, and glandular tissue; provides protection, absorption, filtration, and secretion
Term
Apical surface
Definition
Unattached edge of epithelium that is exposed to body exterior or to cavity of internal organ
Term
Epithelial Cell Shapes
Definition
Squamous-flat
Cuboidal-cubed
Columnar-columns
Term
Epithelial Cell Layers
Definition
Simple-one layer
Stratified-More than one layer; mostly for protection
Term
Gland
Definition
One or more cells that make and secrete a particular product
Term
Endocrine Glands
Definition
Ductless; hormonal secretions diffuse directly into blood vessels
Term
Exocrine Glands
Definition
Retain ducts; secretions go to epithelial surface (internal and external)
Term
Connective tissue
Definition
Connects body parts; involved in protecting, supporting, and binding together other body tissues
Term
Extracellular matrix
Definition
Non-living substance found outside cells-secreted by connective tissue
Term
Types of connective tissue
Definition
bone, cartilage, dense/loose, and blood
Term
Muscle tissue
Definition
Specialized to contract in order to produce movement
Term
Types of muscle tissue
Definition
Skeletal, cardiac, smooth
Term
Nervous tissue
Definition
Neurons; receive and conduct electrochemical impulses throughout body
Term
Neuroglia
Definition
Specialized cells that insulate, support, and protect neurons
Term
Neoplasm
Definition
Abnormal cell mass that develops when cell cycle/division malfunctions
Term
Amitotic
Definition
The inability to perform mitosis (cell division) (Ex: cardiac, nervous tissue etc)
Term
Hyperplasia
Definition
Enlarging of organs/tissues due to a local irritant or other condition
Term
Atrophy
Definition
Decrease in size of organs/tissues due to a loss of normal stimulation
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