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Chapter 5
Measuring energy expenditure at rest and during exercise
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Undergraduate 4
10/07/2017

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Term
When you measure heat production by gauging and quantifying the energy production, this is called?
Definition
Direct Calorimetry
Term
When glucose and fat is metabolized it produces ____% ATP but the remaining rest is released as _____
Definition
40%, heat
Term
What are some of the limitations of Direct Calorimetry?
Definition
- Impractical and expensive
- Machines, body temperature can change water temperature
Term
Between Direct and Indirect Calorimetry, what is more precise and accurate?
Definition
Direct
Term
What does indirect calorimetry measure?
Definition
Measures pulmonary respiratory gas exchange
Term
indirect calorimetry is only accurate for what type of metabolism?
Definition
steady state oxidative , were not accounting glycolosis or ATP-Pcr
Term
volume of O2 consumed per minute is called what?
Definition
VO2
Term
What is VO2?
Definition
volume of O2 consumed per minute
Term
Rate of O2 “consumption, where?
Definition
oxygen is the final electron acceptor in the electron transport chain, forming water in the process
Term
Rate of CO2 production from WHERE?
Definition
Krebs Cycle
Term
VCO2: volume of ________ per minute
Definition
CO2
Term
Between Glucose and Palmitic acid, which one would need more oxygen and why?
Definition
Palmitic Acid because it has more carbons
Term
Does having more carbon require needing more oxygen or less?
Definition
More Oxygen
Term
How much carbon does glucose and palmitic acid have?
Definition
Glucose has 6 and Palmitic Acid has 16
Term
Respiratory Quotient (RQ) is the ratio between rates of CO2 production and O2 usage during __________ respiration
Definition
cellular respiration
Term
What is Respiratory quotient and it's formula
Definition
It is the measure of the ratio between rates of CO2 production and O2 usage during cellular respiration. The formula is VCO2/O2
Term
What is Respiratory Exchange Ratio?
Definition
It is the estimate of the Respiratory Quotient from Pulmonary Respiration
Term
What is the estimate of the RQ from pulmonary respiration?
Definition
RER or Respiratory Exchange Ratio
Term
Does the RER work well?
Definition
Works well for most part since little O2 reserve inside body.
Term
If you had 16 CO2 and you had 23 O2, what would be the RQ(Respiratory Quotient)
Definition
16/23 = 0.70
VCO2/VO2
Term
If you had 6 CO2 and 6O2, what would be the RQ(respiratory quotient)?
Definition
6/6 =1 RQ
Term
If the RER was close to 1.0, we can say which substrate was being used?
Definition
Carbs
Term
If the RER was close to 0.7, we can say which substrate was being used?
Definition
Fat
Term
RER can be used as an Estimate of RQ to estimate substrate usage, T or F?
Definition
True
Term
Energy usage per liter of oxygen varies with the type of fuel, T or F
Definition
True for example (4.59 - 5.05kcal/L)
Term
If a person had a RER of 1.0 and generates 5.0 kcal per oxygen L and we measure someone consuming 2L of 02 per min, we can assume they are using ____ of energy per min
Definition
5x2=10
Term
as RER increase its value, which substrate would be used more?
Definition
Carbs
Term
In the crossover concept of fuel utilization, as exercise intensity increases, the total energy contribution comes from which substrate?
Definition
Carbs
Term
To increase pace/intensity, what must one do? How do we use our muscles to do this?
Definition
Recuruiting Motor Units . For example, if you were sprinting, or running, you would need to use more fast glycotic fibers and the opposite is true as we decrease the intensity
Term
How does the body respond to the increasing stress of the above progression and how does this in turn influence substrate utilization
Definition
releasing hormones such as norephinephrine, adrenal.
Term
The Enzyme "Phosphorylase" stimulates which muscle fibers and what are the values?
Definition
Type 2A(Fast Oxidative Glycotic) at 5.8 and Type 2x(Fast Glycotic) at 8.8
Term
Fast Glycotic systems are built for Glycolosis but has smaller _________ and needs to generate ______ fast when recruited
Definition
Mithochondria; ATP
Term
In the Mithochondria, what are the values % of the total fiber volume of Type 2a and Type2B
Definition
3.1 for Type 2x and 3.6 for type 2a
Term
During Brisk walking, which substrates are used(kcal/min) and what is the total kcal per minute?
Definition
Brisk walking - 3kcal from fat and 2 from carbs, total of 5 kcal per min
Term
During moderate jogging, which substrates are used(kcal/min) and what is the total kcal per minute?
Definition
Moderate jogging, 3kcal from fat and 5 from carbs using 8 kcal per min total
Term
During sprinting, which substrates are used(kcal/min) and what is the total kcal per minute?
Definition
2kcal from fat and 10kcal from carbs which is total of 12 kcal per minute
Term
Comparing people who do low intensity vs high intensity who burn 300kcal total, who would need to metabolize more fat post exercise?
Definition
high intensity
Term
A major limitation of indirect calorimetry is that Metabolic CO2 does not equal what?
Definition
The total co2 that the body is pexhaling, therefore inaccurate during cellular respiration
Term
what is the buffering system for H protons?
Definition
Bi-Carbonate
Term
A major limitation of indirect calorimetry is that Metabolic CO2 does not equal to the total CO2 produced. Furthermore, the co2 is non metabolic that does not come from Krebs Cycle. T or F
Definition
True
Term
Why is RER inaccurate for protein oxidation?
Definition
Because protein does not completely oxidize
Term
Gluconeogenesis produces an RER of .70, why is this a limitation of indirect calorimetry?
Definition
Because it will skew the RER
Term
An indirect calorimetry does not underline the source of carbs or fat, in what sense?
Definition
Because we don't know if the carbs are coming from glycogen or glucose. Also, we don't know if the fat is from FFA or triglycerides
Term
What is BMR and how do exercise physiologist measure BMR?
Definition
BMR is the minimum energy requirement for living and they measure after 8 hrs of sleep, 12 hrs of fasting and in a supine position.
Term
What can affect the BMR?
Definition
Body temp., age, stress, etc.
Term
What is RMR and how does it relate to BMR?
Definition
It is the resting metabolic rate and usually 5-10% of BMR.
Term
Why is RMR easier as a measuring stick vs. BMR?
Definition
Because RMR does not require stringent standardizations
Term
What is metabolic rate?
Definition
The rate of energy the body uses
Term
What is metabolic rate based on?
Definition
Based on whole body O2 consumption and how much calories the corresponding caloric equivalent.
Term
At rest, generally the body has an RER of how much? and how much vo2
Definition
about .80 rer and also vo2 is - .3L/min
Term
At rest VO2 relative to body mass = ~ _____/kg/min and this value is called a MET (metabolic equivalent).
Definition
3.5ml; this is the standard number scientists use to compare
Term
Energy Expenditure During Submaximal Aerobic Exercise. Does energy use and vo2 go up linearly or curvelinearly as work increases?
Definition
linearly
Term
what is VO2 max?
Definition
maximal oxygen consumption. Point at which O2 consumption doesn’t go up with further increase in work/intensity (it plateaus
Term
what is the best predictor of aerobic fitness capacity but not the best for endurance?
Definition
VO2 max
Term
Why is VO2 max not a good measurement of endurance?
Definition
Because the pace is not sustainable
Term
what is the difference of the vo2 between a trained and untrained individual during exercise?
Definition
The trained person can go much faster at a certain %. (For example, 80%)
Term
Best NOT to compare VO2 without accounting for _____ of person
Definition
Size
Term
Absolute VO2 is measured in what units?
Definition
Liters/Min
Term
Larger people have larger or smaller values of VO2?
Definition
larger
Term
What units is RELATIVE VO2 measured in?
Definition
ml/kg/min
Term
Abs. VO2 in mL/min divided by mass (kg). True o False
Definition
True
Term
the average vo2 max for an untrained man and women is?
Definition
untrained men is 44-50 ml/kg/min
untrained women is 38-42 ml/kg/min
Term
Avg. Resting VO2 is ____ ml/kg/min and this is called a MET
Definition
3.5
Term
If the person had a VO2 max of 35 ml/kg/min and humans average MET is 3.5. How much Met max is that?
Definition
10 METS
Term
How does the metabolic ladder work?
Definition
[image]
Term
There are activities that are 100% anaerobic and 100% aerobic. True or false?
Definition
False, no activity is 100% anaerobic or aerobic
Term
What does it mean by O2 deficit?
Definition
When aerobic exercise begins, the oxygen transport system (respi- ration and circulation) does not immediately supply the needed quantity of oxygen to the active muscles.
Term
O2 “required” < O2 consumed
Definition
due to orderly metabolic recruitment
Term
O2 consumed > O2 demand in early recovery
Definition
Excess Post-exercise O2 Consumption (EPOC)
Replenishes ATP/PCr stores, converts lactate to glycogen, replenishes hemo/myoglobin, clears H+ and CO2
Term
What is lactate threshold?
Definition
The point where blood lactate starts to accumulate
Term
What is this term called?
Blood lactate appearance rate > disappearance rate
Good indicator of potential for endurance events
Indirect indicator of potential metabolic acidosis since H+ are released and co-transported with Lactate
Usually expressed as percentage of own VO2max
Definition
lactate threshold
Term
What is the term called when H proton causes fatigue?
Definition
Muscle Acidosis
Term
Blood Lactate measures are a useful ______ measure since Lactate and H+ are co-transported out of _____ when Hydrolysis and Glycolysis rates are ____ and thus producing more H+.
Definition
indirect, muscle, high
Term
Is lactic acid and or lactate the cause of fatigue?
Definition
No, it is not
Term
Lactate Formation Facilitates continuation of Glycolysis since NAD is reformed in the process and Lactate allows for transport of H+ out of the cytosol. True or False
Definition
True
Term
What are the confusing terms of Lactate Threshold?
Definition
Common terms, lactate infection point, maximal steady state (MLSS), onset of blood lactate accumulation OBLA
Term
What is the difference between LT1 and LT2?
Definition
LT2 is at a higher intensity compared to LT1, furthermore LT2 is what is typically used in the textbooks about how blood lactate has more appearance rate vs clearance rate.
Term
Average untrained LT occurs at how many % VO2 max
Definition
50 to 60
Term
Trained endurance athlete occurs at % VO2 max
Definition
70 to 90
Term
why is lactate threshold performance better than vo2 max?
Definition
because of its sustainable pace
Term
does LT2 test reflect highest blood lactate?
Definition
NO
Term
What is Highest workload you can sustain & lactate levels remain constant (more importantly H+?
Definition
Maximal Lactate Steady State
Term
What is Maximal Steady State?
Definition
It is the highest workload you can sustain but lactate levels remain constant
Term
What happens if you start training above Max Lactate Threshold?
Definition
Hydrogen ions will rise and also the production of lactate will be more than it can clear from muscle even if the pace was steady
Term
The MLSS is roughly equal to ___K or a half marathon pace or a 20 to 40 k on a bike (20 to 60 min)
Definition
10k
Term
What component of force plays a significant role in Economy?
Definition
Elasticity
Term
What are the 4 components that make an endurance athlete successful?
Definition
1) high vo2 max
2) high lactate threshold
3) high economy of effort
4) high percentage of muscle 1 fibers
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