Term
| Definition of hyperthermia |
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Definition
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Term
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Definition
Core body temp is normal, skin is moist and cool
Occurs in muscles following vigorous exercise in the heat
Caused by salt depletion from excess sweating combined with hypotonic fluid replacement.... dilutional hyponatremia |
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Term
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Definition
Core temp is minimally increased (37-40)
Consequence of Salt and water loss |
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Term
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Definition
Temp > 40.6
Usually during heat wave over several days, usually affects elderly of chronically sick
Can occur in athletes, workers in high heat and humidity without appropriate salt/water
Signs are dehydration, CNS dysfunction, hot & dry skin |
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Term
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Definition
Malignant Hyperthermia
Drug induced genetic susceptibility to sustained skeletal muscle contraction after exposure to depolarizing muscle relaxants such as SUCCINLYCHOLINE, or anesthetic agents such as HALOTHANE or ISOFLURANE.
Duchenne diseases and myotonic muscular dystrophy are associated with malignant hyperthermia |
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Term
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Definition
NMS
Drug induced reaction characterized by hyperthermia, altered mentation, muscle rigidity
Drugs implicated are most often FGAs, or withdrawal of dopaminergic agent eg levodopa.. |
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Term
| Treatment of Malignant Hyperthermia (Think what causes it) |
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Definition
Malignant hyperthermia caused by genetic predisposition to skeletal muscle contraction for long periods of time... Treatment would be a Muscle relaxant!
Dantrolene 2mg/kg IV q5min
can continue dantrolene in oral regimen for 2-3 days after |
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Term
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Definition
| Bromocriptine (dopaminergic agonist) and dantrolene (muscle relaxant) |
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Term
| Passive External Rewarming |
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Definition
| Minimize heat loss by removing wet clothing, and keep pt dry with warm blankets. Relies on pts shivering to warm back up (this is lost below 32 C, so need to do more if that is the case) |
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Term
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Definition
| Heat blanket or warm immersion... Not too hot to avoid vasodilation. Limit heating to the trunk. |
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Term
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Definition
eg. Heated (40-43) IV NS through central line. Cannot heat blood as proteins will be destroyed.
Really any invasive procedure to warm body |
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Term
| Hypothermia is often associated with alcohol intoxication... What supplement should be given? |
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Definition
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Term
| Muscle relaxant used to prevent shivering in hypothermia? |
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Definition
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Term
| What electrolyte should be monitored when reheating in hypothermia? |
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Definition
| K+, hyperkalemia can be induced by rewarming |
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