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Chapter60
GERD - Gastroesophageal Reflux Disease
8
Medical
Professional
10/04/2011

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Cards

Term
When should Rx be considered?
Definition
Frequent severe pain, nocturnal symptoms, or complications
Term
Things that worsen GERD
Definition
OBESITY & PREGNANCY, caffeine, acidic juices, large fatty meals, spicy foods, lying down after meals, alcohol, smoking, overweight

TCAs BBs anticholinergic agents, theophylline, CCBs
Term
Treatment options for mild GERD
Definition
OTC antacids, H2 blockers, alginates
Term
DOC for GERD, when should they be taken?
Definition
DOC: PPIs (-prazoles)
Term
Algorithm for PPI use
Definition
Use in moderate-severe patients for 2-4 weeks, if no response then double dose to twice daily. Stop if there is a good response, if there is recurrence long term PPI with minimum effective dose
Term
Which anti-GERD class is NOT recommended in breastfeeding women?
Definition
PPIs not recommended in breastfeeding women, Use ranitidine.

Can use all of them in pregnancy
Term
Side effects of H2 Antagonists

Drug interactions of H2 Antagonists
Definition
Diarrhea, constipation, HA, Gynecomastia, cardiac effects.

Cimetidine - Huge p450 inhibitor
Term
Side effects of PPIs
Definition
HA, Nausea, Rash
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