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Clin Pharm Exam 1
Clin Pharm Exam 1
105
Other
Graduate
06/23/2010

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Term
What is the relationship between a teaspoon (tsp), cc/ml and gtts (drops)?
Definition
1 tsp = 5cc's/ml or 75 gtts (drops)
Term
What is the relationship between 1 tablespoon (tbs) and mL's?
Definition
1 tbs = 15 mL's
Term
What is the relationship between 1 ounce, tablespoon and mL's?
Definition
1 ounce = 2 tablespoons = 30 mL's
Term
What is the relationship between teaspoons and table spoons?
Definition
1 tablespoon(tbs) = 3 teaspoons (tsp)
Term
What is the relationship between drops (gtts) and mL's?
Definition
1mL = 15 drops (gtts)
Term
Calculate the dose of Keflex for a 20 kg child assuming we want 75 mg/kg/day divided QID.
Definition
375 mg PO q 6h
Term
What are the major SEs seen with Cipro and Doxycycline?
Definition
Cipro = tendon rupture under 18 years old.
Doxy = photosensitivity
Term
What are the only antibiotic drops that can be used with a perforated TM?
Definition
Ciprodex
Term
What are the first line treatment options for Otitis Media?
Definition
1st line = Amoxicillin or Augmentin.
2nd line = Omnicef (3rd gen cephalosporin)
Term
What is the treatment for chronic otitis externa?
Definition
Cortisporin otic (Neomycin/polyB/corticosteroid)
Term
What is the treatment for fungal otitis media?
Definition
fluconazole (Diflucan)
Term
What are the treatment options for malignant otitis externa?
Definition
Merrem (carbepenum) is first line but most people use IV Cipro
Term
What are the treatment options for acute otitis externa (Swimmer's ear)?
Definition
Cortisporin (neomycin/polyB/hydrocortisone)
Oflaxacin otic
Dicloxacillin
Cipro HC otic
Term
What is the treatment for Mastoiditis?
Definition
Cipro
Term
What is the treatment for an Ear abscess?
Definition
I&D and bactrim
Term
What is the treatment for a cerumen impaction?
Definition
No antibiotics, try OTC Debrox or lubricants that have peroxide in them
Term
What is the treatment for an insect foreign body in the ear?
Definition
Lidocaine and removal
Term
What are the treatment options for mild-moderate bacterial conjunctivitis in a non-neonate? Moderate to severe?
Definition
Mild-Mod =
Azithromycin
Bleph-10 (sulfacetamide)

Mod-Severe =
Quinolones

*all soln
Term
What are the treatment options for allergic conjunctivitis?
Definition
Benadryl, Claritin, Zyrtec, Palgic, or Allegra
Term
Why should you be careful giving Benadryl to someone with asthma?
Definition
It thickening pulmonary secretions
Term
What is the treatment for Blepharitis?
Definition
warm compress, artificial tears and baby shampoo
Term
What is the treatment for a Hordeolum/Stye? What if it is caused by MRSA?
Definition
Dicloxacillin + hot pack.
MRSA = Bactrim
Term
What is the treatment for a corneal abrasion? What if it is in a contact lens wearer?
Definition
Erythromycin or Bacitracin ointment and pain meds.
Contact lens = Cipro.
Term
What do you want to avoid with any viral eye infection?
Definition
Steroids, it can worsen it.
Term
How do you treat Herpes Keratitis? 2nd line? How do you prevent recurrence?
Definition
1st line = Trifluridine drops.
2nd line - Vidarabine ointment.
Prevent recurrence with acyclovir.
*all are antivirals
Term
How do you treat scleritis?
Definition
Steroids or NSAIDs, no abx
Term
How can you treat Iritis?
Definition
Cyclogyl, Isopto or Prednisolone. (anticholinergics or steroids)
Term
How do you treat orbital cellulitis if MRSA is not suspected? If it is? What if they have a PCN allergy?
Definition
No MRSA = Nafcillin IV
MRSA = Vanco+Rocephin+Flagyl IV
PCN allergy = Vanco+Levaquin+Flagyl
*Admit patient!
Term
What are the treatment options for Periorbital Cellulitis? Severe?
Definition
Keflex, Unasyn, Cleocin, Bactrim, Doxy or Vanco.
Severe = Cleocin (clindamycin)
Term
What are the main side effects of Vancomycin? Why must you inject it slow?
Definition
Main SEs = SJS and it is ototoxic.
Inject slow to prevent Redman Syndrome causing hypotension.
Term
What is the PEDS dosing ratio of trimethoprim(TMP) to sulfamethoxazole(SMZ) in bactrim?
Definition
40/200
Term
Suppose you have a 12 kg child and he needs 20 mg/kg/day of TMP and you want to give it TID. How many mL's does he need to take assuming a ratio of 40/200 Bactrim per 5mL's of suspension?
Definition
10mL's TID to get his 240 mg of TMP
Term
What is the treatment for bacterial pharyngitis? How long should you treat?
Definition
PCN, Macrolide or 2nd generation Cephalosporin with possible steroid if airway compromise.
Treat for 10 days.
Term
What is the treatment for gonococcal pharyngitis?
Definition
Rocephin IM + Doxy or Zithromax for chlamydia coverage
Term
What type of analgesic should you use for a sore throat? SEs?
Definition
Viscous lidocaine
SEs = hypotension and arrythmias
Term
What is the first line treatment for Epiglottitis?
Definition
1st line = 3rd gen Ceph (Rocephin /Claforan).
Term
What are the first line treatment options for a retropharyngeal abscess?
Definition
Clindamycin or PCN with Flagyl
Term
What is the mainstay treatment for Laryngitis? What can it progress to?
Definition
voice rest and humidified air, it can become Croup.
Term
What is the first line treatment option for acute sinusitis? Second line if allergy?
Definition
1st line = Amoxicillin, Augmentin or Cephalosporin.
2nd line if PCN allergy = Quinolone or Macrolide.
Term
What is the preferred allergic rhinitis med for those under 4-5 years old?
Definition
Nasonex
Term
What is the pharmacologic treatment regimen for an MI?
Definition
MONA + Heparin or Lovenox
Term
What is the treatment for Prinzmetals angina?
Definition
CCBs
Term
What is the main concern with the CCB/statin: Caduet (amiodipine/atorvastatin)?
Definition
Liver function, monitor LFTs
Term
What is the main contraindications for the CCB: Cardiazem (diltiazem)?
Definition
Sick Sinus Syndrome, 2nd/3rd degree heart block, acute MI or pulmonary edema.
Term
What are the main contraindications to the Beta Blocker: Inderal (propranolol)?
Definition
asthma, bradycardia, heart block or CHF
Term
What is the major drug class that nitrates interact with?
Definition
Phosphodiesterase inhibitors (Viagra, Levitra, Cialis)
Term
What are the main contraindications to the CCB: Nicardipine?
Definition
Advanced aortic stenosis and Tagamet use as it increases the effects of Nicardipine.
Term
What is the main contraindication to ACEi use in CHF?
Definition
Hx of angioedema
Term
What is the indication, main contraindication and major SEs of Amiodarone?
Definition
Indication = unstable ventricular arrythmias.
Contraindication = 2nd/3rd degree AV block.
SEs = pulmonary fibrosis, corneal deposits, optic neuropathy.
Term
What is the indication, major contraindication and main adverse effects of Digoxin?
Definition
Indication = chronic A fib.
Contraindication = v fib.
SEs = CNS effects and blurred vision.
Term
What is the best treatment for high triglycerides?
Definition
Niacin
Term
What is the main contraindication to statin (Crestor/Lipitor) use? Which cholesterol levels do statins work on?
Definition
Main contraindication = Liver disease.
Use = drops LDL and total cholesterol levels.
Term
The indication for this drug is when trigs are over 1000mg/dL and pancreatitis is likely
Definition
The Fibrate (Lopid)
Term
What is the main contraindication to the Fibrate (Trichor)?
Definition
Gallbladder disease
Term
What is the main contraindication to the Bile Adid Binding Resin (Welchol)?
Definition
Bowel obstruction
Term
What are the rapid acting HTN meds?
Definition
Nitroprusside, Nitroglycerine, Labetalol, Hydralazine and Nicardipine.
*Clonidine is kind of fast.
Term
What are the 2 main causes of Bronchiolitis? Treatment?
Definition
RSV (50%) and Parainfluenza virus (25%).
Oxygen is mainstay treatment and Ribavirin in certain cases.
Term
How do you treat acute bronchitis?
Definition
Usually with bronchodilators and anti-tussives.
Term
How do you treat Pertussis?
Definition
Macrolide antibiotic or Bactrim if the bacteria is resistant.
Term
How do you treat pneumonia in a 4 month to 5 year old? What if they are admitted?
Definition
Tx = Amoxacillin.
If admitted = Ampicillin or Rocephin.
Term
What are the treatment options for an outpatient 5-15 year old with pneumonia?
Definition
AMoxicillin, Biaxin, Zithromax
Term
What are the adult treatment options for pneumonia?
Definition
Macrolides, Doxy, Augmentin, Quinolones, amoxicillin or Cephalosporins
Term
What is the treatment regimen for an adult hospitalized pneumonia patient? ICU?
Definition
Hospitalized = Rocephin + Zithromax.
ICU = Avelox or Levaquin.
Term
What is the treatment for aspiration pneumonia leading to a lung abscess?
Definition
Zosyn IV
Term
What is the treatment for an HIV patient with bronchitis or pneumonia?
Definition
They respond well to Bactrim DS
Term
When should someone take Tamiflu for FLU treatment?
Definition
within 48 hours of onset of flu symptoms
Term
How long should someone wait to take get a flu shot if they have had tamiflu?
Definition
2 weeks
Term
What is the most common use of Ancef in orthopedics?
Definition
Used IV as a pre-operative antibiotic
Term
What is the common orthopedic use of Keflex, Duracef and Omnicef?
Definition
Soft tissue infections
Term
What are the considerations to keep in mind when prescribing Ultram or Ultracet as pain meds?
Definition
They can be addicting and they lower the seizure threshold.
Term
What is the major contraindication to Tylenol with Codeine use?
Definition
Elevated LFTs
Term
Which pain meds are considered moderate to heavy?
Definition
Nubain, Vicodin, Ultracet and Ultram
Term
Which pain meds are considered "hardcore"?
Definition
Demerol, Dilaudid, Percocet, Fentanyl, Percodan, Oxycodone and Morphine
Term
What are the uses of Lyrica?
Definition
RSD and fibromyalgia
Term
Which muscle relaxer is used against MS and muscular dystrophy?
Definition
Baclofen
Term
Which muscle relaxers can be used with pregnancy?
Definition
Flexeril and Amrix
Term
What is the most common class of drugs used to treat nausea and vomiting?
Definition
Phenothiazines (Compazine and Phenergan)
Term
What is the most common side effect of Phenothiazines (Compazine and Phenergan)? Can they be used in pregnancy?
Definition
Most common SE is CNS depression/sedation.
They cannot be used in pregnancy (category C).
Term
What are the most common SEs of the antihistamine anticholinergic transdermal scopolamine patch?
Definition
blurry vision, dilated pupils, urinary retention and dry mouth
Term
When would you use Helidac over Prevpac for H. pylori infection?
Definition
PCN allergy
Term
What is the main contraindication to Aciphex use?
Definition
Renal disease because it works through bicarb system
Term
Which H2 Blocker and PPI are notorious for having many drug interactions?
Definition
H2 = Tagamet.
PPI = Prilosec.
Term
Which drugs/classes has Tagamet been known to increase the concentration of by inhibiting the P450 enzymatic breakdown of the drug?
Definition
anticoagulants, benzodiazepines, theophylline, phenytoin, nifedipine and propranolol
Term
What are some common PPI's? What do their names end in?
Definition
End in "-azole".
Aciphex, Nexium, Prevacid, Prilosex and Protonix
Term
What are some common H2 blockers? What do their names end in?
Definition
end in "-tidine"
Axid
Pepcid
Tagamet
Zantac
Term
Which drug used to treat DM II commonly causes diarrhea? Most dangerous SE?
Definition
Metformin, can cause lactic acidosis.
Term
Should anti-diarrhea agents be used in patients with parasitic or some bacterial infections such as shigella?
Definition
No
Term
What is the treatment for Amebiasis and Giardiasis and C. diff?
Definition
Metronidazole
Term
What is the major concern with a patient taking Flagyl?
Definition
Disulfiram like reaction, do not drink.
Term
What are the treatment options for chronic diarrhea?
Definition
Opiates (Imodium and Lomotil)
or
Absorbents (Pepto-Bismol and Kaopectate)
Term
What are the treatment options for constipation?
Definition
increased fiber diet or supplementing the diet with bulk-forming agents such as Metamucil.
Term
Should you use agents that stimulate peristalsis if intestinal obstruction is a possibility?
Definition
Nope
Term
What is the use of Methergine in OBGYN?
Definition
post-partum bleeding and ectopics
Term
What is the use of Methotrexate in OBGYN?
Definition
ectopic pregnancy
Term
What is the use of Oxytocin in OBGYN?
Definition
Labor induction, stimulate contractions and post-partum bleeding
Term
What is the best anti-emmetic drug to use during pregnancy? Why?
Definition
Zofran because it is less sedating than phenergan.
Term
What is the risk of pushing more than 25mg of Phenergan at a time?
Definition
Risk of gangrene & respiratory depression
Term
What drugs can we use to stop contractions in pregnancy?
Definition
Magnesium sulfate, terbutaline and glucocorticoids
Term
What drugs do we use for pre-eclampsia/eclampsia?
Definition
Magnesium sulfate and anti HTN drugs
Term
What are the main SEs of iron supplementation for mild anemia in pregnancy?
Definition
constipation and green stool
Term
What is the major risk of not treating STDs or other pelvicc infections during pregnancy?
Definition
PROM
Term
What do you use to treat trichomonas during pregnancy?
Definition
Flagyl, but try to avoid in the 1st trimester
Term
What do you use to treat yeast infections during pregnancy?
Definition
topical clotrimazole
Term
What is the treatment for bacterial vaginitis/vaginosis in pregnancy?
Definition
Flagyl, try to avoid in first trimester.
Term
How do we treat dysfunction uterine bleeding?
Definition
Progestin class drugs, end in "-thindrone"
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