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C5a > C3a, C4a = anaphylatoxins |
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Opsonic and adhesion receptors |
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C5aR > C3a/4aR Mast cell, basophils, smooth muscle |
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Clearance receptor (soluble) |
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Stabilization of C3b and C4b by binding things with an amino group (antigen surface proteins) |
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Binds to and inhibits C4b joining C2a and forming a C3 convertase |
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Binds C5b67 and prevents it from binding C8 and ultimately the MAC complex |
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Stabilizes C3 convertase forming C3bBbP |
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Complement receptor that block C3 convertase formation |
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Decay accelerating factor; induces C3 convertase decay |
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Binds to C3b preventing C3bBb formation |
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Cleaves and inactivates C3b and C4b generating iC3b and iC4b |
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Cleaves and inactivates C3a, C4a, and 5a |
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blocking proteolysis stabilization dissociation |
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