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Comprehensive Drug Review
VET 1400 Pharmacology Drugs
60
Pharmacology
Not Applicable
02/15/2011

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Cards

Term
What are the effects of expectorant drugs?
Definition
They increase the flow of respiratory secretions to allow material to be coughed up from the lungs.
Term
What effects do mucolytic drugs have?
Definition
They decrease the viscosity (thickness) of respiratory secretions.
Term
If a cough is productive should it be supressed?
Definition
No, because it is expelling the unwanted secretions from the body.
Term
Describe the effects and uses of guaifenesin.
Definition
-In animals it has minimal expectorant activity.
-It can be used for mild sedation and analgesic properties.
-In equines, it is an adjunct to anesthetics.
-It can assist in intubation because it relaxes smooth muscle.
Term
Describe the effects and uses of acetylcysteine.
Definition
-If nebulized it will cause significant bronchoconstriction.
-It is the antidote for acetaminophen toxicity.
Term
What is an antitussive?
Definition
These drugs suppress the cough reflex either centrally (systemic) or locally (cough drops).
Term
T or F Dextromethorphan is an antitussive commonly used in vet medicine.
Definition
F Dextromethorphan is not effective in non-human species.
Term
How does a decongestant work?
Definition
It reduces swelling in the nasal cavities that causes congestion.
Term
What type of drug are phenylephrine and pseudoephedrine?
Definition
Decongestants.
Term
When using phenylephrine or pseudoephedrine, what will you monitor for specifically?
Definition
Tachycardia.
Term
T or F An antihistamine is often used in place of a decongestant in animal medicine.
Definition
T Antihistamines may have decongestant effects and are a safer alternative to available decongestants.
Term
What side effects might you see with use of antihistamines?
Definition
-CNS depression.
-Anticholinergic effects.
Term
What does the acronym SLUDDE stand for?
Definition
Salivation, lacrimation, urination, defecation, dyspnea, and emesis.
Term
What effect does a bronchodilator have?
Definition
These drugs widen the lumen of the bronchi and counteract bronchoconstriction.
Term
Atropine and glycopyrrolate are in what group of drugs? What do they counteract?
Definition
-Acetylcholine blocking agents (Anticholinergics)
-Bronchoconstriction
Term
The beta-2 adrenergic agonist epinephrine will only be used in what circumstance?
Definition
Emergency only.
Term
Isoproterenol, terbutaline and albuterol are in what group of drugs?
A. Catecholemines
B. Sodium channel blockers
C. Antihistamines
D. Beta-2 Adrenergic agonists
Definition
D Beta-2 Adrenergic agonists
Term
What bronchodilators are safe enough to be sent home for owners to dose their asthmatic pets?
Definition
The methyxanthines; aminophylline and theophylline.
Term
Respiratory stimulants will have what effect?
Definition
Stimulates the animal to increase its respiration.
Term
What drug stimulates neonatal respiration after a c-section?
Definition
Doxapram
Term
The antidote for opioid overdose.
Definition
Naloxone
Term
Reverses xylazine.
Definition
Yohimbine
Term
What effect will a positive inotrope produce?
Definition
Increases contractility.
Term
What effects will a negative inotrope produce?
Definition
Decreases contractility, decreases the workload of the heart.
Term
The two types of positive inotropes include what groups of drugs?
Definition
Cardiac glycosides and catecholemines.
Term
What effects will cardiac glycosides, like Digoxin and Pimobendan, have?
Definition
-Increase the strength of cardiac contractions
-Decrease the heart rate
-Antiarrhythmic effects
-Decreased signs of dyspnea
Term
Why must Digoxin blood levels always be monitored in patients receiving it?
Definition
It has a narrow theraputic window.
Term
Epinephrine, Dopamine and Dobutamine are in that group of drugs?
A. ACE inhibitors
B. Catecholemines
C. Glucocorticoids
D. MAOIs
Definition
B Catecholemines
Term
Catecholemines, positive inotropic drugs, will have what effects in the body?
Definition
-Increase the force and rate of myocardial contraction
-Constrict peripheral blood vessels
-Increase blood glucose levels
Term
What side effects would you possibly note with Atenolol?
Definition
Bradycardia, lethargy, depression, arrhythmias, and dyspnea.
Term
Sodium channel blockers, calcium channel blockers and beta blockers are all used to treat what condition?
Definition
Arrhythmias.
Term
What are some of the uses for Lidocaine?
Definition
Antiarrhythmic drug of choice for PVCs and other ventricular arrhythmias; local anesthetic.
Term
Lidocaine will cause toxicity in what species of animal?
Definition
Cats.
Term
Atenolol, a beta blocker, is used to treat what conditions?
Definition
Treats tachyarrythmias and hypertrophic cardiomyopathy.
Term
T or F Calcium channel blockers are negative inotropic drugs.
Definition
T
Term
Diltiazem will have what effects on an animal?
Definition
Slows down electrical conduction in the heart; decreases heart rate. Vasodilation; decreases blood pressure.
Term
Diltiazem and amlodipine are what type of drug?
Definition
-Cardiac drugs.
-Calcium channel blockers.
Term
What is the drug of choice to treat hypertension in cats?
Definition
Amlodipine.
Term
An ACE inhibitor works by what method of action?
Definition
It prevents conversion of angiotensin I into angiotensin II, a vasoconstrictor.
Term
What does the acronym ACE stand for?
Definition
Angiotensin converting enzyme.
Term
How will Enalapril (ACE inhibitor) treat congestive heart failure?
Definition
-Decreases water retention.
-Vasodilator.
-Mild effects on decreasign blood pressure.
Term
What effects will a diuretic have? Name the most commonly used diuretic in veterinary medicine.
Definition
-Increases fluid excretion by the kidneys.
-Furosemide. (Lasix)
Term
What is the method of action for an anticoagulant?
Definition
They inhibit clot formation by inactivating one or more clotting factors.
Term
Iron and erythropoietin are supplemented to treat what condition?
Definition
Anemia.
Term
Antihistamines, benzodiazepines, phenothiazines and azapirones will all treat what general behavioral problem?
Definition
Anxiety.
Term
This common benzodiazepine is a GABA agonist that will produce sedation and relieve anxiety.
A. Alprazolam
B. Clomicalm
C. Diazepam
D. Selegiline
Definition
C Diazepam
Term
This phenothiazine is contraindicated in epileptic patients because it lowers the seizure threshold.
Definition
Acepromazine
Term
Side effects of azapirones, like buspirone, include what?
Definition
-Does not cause sedation
-Boosts confidence
Term
MAOIs like selegiline are used to treat what condition?
Definition
Cognitive dysfunction (senility)
Term
Amitryptaline and clomipramine are what type of behavior drug?
A. MAOIs
B. Tricyclics
C. Phenothiazines
D. SSRIs
Definition
B Tricyclics; these drugs interfere with the reuptake of neurotransmitter by the presynaptic nerve.
Term
By what mechanism of action do selective serotonin reuptake inhibitors (SSRIs) work?
Definition
They inhibit serotonin reuptake.
Term
Fluoxetine, sertraline, and paroxetine are examples of what type of antidepressant?
Definition
Selective serotonin reuptake inhibitors (SSRIs)
Term
Progestins and estrogens will suppress what type of behaviors?
Definition
Male-like behaviors.
Term
The two most popular induction agents are combinations of what drugs?
Definition
Ketval (Ketamine and diazepam)
Tilazol (Tiletamine and zolazepam)
Term
What serious side effect can acepromazine have in stallions?
Definition
Penile prolapse
Term
Name two alpha-2 agonist pre-meds commonly used.
Definition
Dexmedetomidine/medetomidine
Xylazine
Term
T or F Atipamezole will reverse the effects of Xylazine.
Definition
F Atipamezole will reverse Dexmedetomidine and yohimbine will reverse xylazine.
Term
This dissociative drug can cause apnea when it is first administered.
Definition
Ketamine
Term
Patients administered this dissociative drug will wake up very slowly and have a long recovery from surgery.
Definition
Telazol
Term
Sight hounds are highly sensitive to this barbiturate drug.
Definition
Thiopental
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