Term
|
Definition
phases of lung development. Canalicular is from 16-24 weeks and saccular is from 24-35 weeks
if born in canalicular phase, infant has a lot of trouble breathing (hyaline membrane disease, RDS) |
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Term
| define bronchopulmonary dysplasia |
|
Definition
| requirement of a ventilator >28 days in a infant born under 32 weeks |
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Term
| what is chorioamnionitis? |
|
Definition
acute inflammation of the amnion (large epithelial barrier (implicated in preterm birth)
some bugs that may cause this are:
group B strep
staph aureus
eterococci
e. coli
fusibacteria
(maybe mycobacteria) |
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Term
| name some things other than chorioamnionitis that are implicated in preterm birth. |
|
Definition
Bugs: Trichomonas, Chlamydia, Garnerella vaginalis, Ureaplasma Urealyticum
TLR4 activation |
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Term
| listeria can infect the fetus and cause... |
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Definition
| meningitis, rash, abscesses |
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Term
|
Definition
| part of brain undergoes an infarct during development and doesn't regenerate and develop normally |
|
|
Term
| name some congenital problems caused by in-utero vascular accidents... |
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Definition
porencephaly
gastroschisis (guts outside body: failure of body-wall development)
intestinal atresia (intestinal lumen doesn't develop)
transverse limb |
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|
Term
| hamartoma and heterotopia definitions |
|
Definition
pediatric tumors:
hamartoma is a focal overgrowth of mature tissue
heterotopia (choristoma) is ectopic tissue |
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Term
|
Definition
| hemangioma, lymphangioma, teratoma |
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|
Term
| pediatric malignant tumors: |
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Definition
| CNS, hematopoetic, soft tissue, bone, kidney, |
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|
Term
| carcinomas (epithelial tissue) is most common tumor in adults, by contrast pediatric tumors mostly come from |
|
Definition
| mesenchymal tissue (sarcoma) |
|
|
Term
| neuroblastomas usually arise where? |
|
Definition
adrenal glands (sympathetic NS)
n-myc amplification |
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