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1)What is Connective tissue |
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- 1/4 basic tissue -derivedfrom mesoderm -loose connective tissue -blood nerves, lymphatics -defense, injuries |
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2) What is dense regular connective tissue |
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3) what is dense irregular |
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-reticular layer of dermis -submucosa of digetive organs |
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-insulation -storage of energy |
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5)what is connective tissue made from |
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-fibers -ground substane -cells |
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6)what is ground substance |
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-amorphous -cololess -homogenous |
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7) what is ground substance made from |
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-proteoglycans -glycoprotiens -tissue fluid |
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-synthe;d, secreted by resident connective tissue -protien backbone -hydrophyllic |
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11)what is hylaine cartilage made of |
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-white amorphous material made of typ2 collagen |
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-small protiens can leave cap's, enter tissue fluid -similar composition as plasma -little in connectie tissue -accumaltion -> edema |
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13) major tpes of fibers? |
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-collagen -elastiv -reticular |
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-19 types -1 to 4 are common -type on is typical -acidophilic |
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-made of elastin ( composed of fibrillin) -need special stains -in blood vessels |
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-abrnormal expression on fibrillin -casues abnormal elsatic tissue -cardio implilcations ->elstic aorta |
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-type 3 collagen -thing, silver salts stain -in lymph and spleen -compose the reticular lamina, below basal lamina |
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18)what are teh connective tissues? |
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19) resident connective tissue? |
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-fibroblas -asipose -other special CT |
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-mast -plasma -leukocytes -macrophages |
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-most abundant -synth extracellular matrix |
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-hard to distinguish from other fibro -contains actin -contractlie -abundant in wound healing |
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-fat -derived from mesnchyme -have basal lamina |
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-large fat broplets -energy storage -insulation -cushioning -common in adults |
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-cells have multiple droplets -fetal life -hibernating animals |
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26)how are lipids stored? |
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-triglycerides transported in blood by protiens -lipoprotiens are broken doen, release fatty acids -esterefied to triglycerides -stored |
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27)how are lipids mobilized |
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-norepenephrine -> camp -> horomone sensetive lipase -hydrolzed triglcerides -can be moved via albumin |
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-large oviod cells -granules -stem cell in marrow -differntiate in connective tissue -granules have vasoavtive, immunoreactive properites |
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29) what is a plasma cell? |
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-antubody producing cell -derived from b lymphocyte -common in loose connective tissue -basophilic cytoplasm -clockface chromatin -large golgi |
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30) mast cell interactions? |
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-ige recpetor on mast cell -plasma cells make ige as response to antigen -triggers mast cell degranulation |
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-derived from blood monocyte -histocyte -phagocytotic -have vacuolated cytoplasm |
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32)what are major migranct celles in CT |
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-lymphocytes -granulatites -neutrophils -eosinophils |
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33) what is a lymphocyte? |
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-part of immune surveillance system -b lympho -> pasma cell -t lymphp -> cell immunity -Natural Killer -> destroy virus |
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34) what is a neutrophils |
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-granulate w/ segmented nuclie -arrives at inflamtion site -leave circutioan vy diapedesis -pus is dead nuetrophils |
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-bilobed nucelus -red granule -allergic, parasit, inflamtion -in gut w/ inflimation |
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-swelling -b/c of fluid accumulaltion in ECM -low osmotic pressure in venule side -high hydrostatic pressure in venule side |
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-lots of cell, few fibers |
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39) where do you have dense irregular ct? |
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-dermis -mostly fibroblasts -organized in many directions, resist stress |
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40)where do you have dense regular ct? |
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-tendons, ligaments -in bundles -fibroblast -stregnth due to covelant bonds |
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41) where do you have loose ct? |
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-under epethelia -around glands |
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