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Connective Tissue
Connective Tissue
32
Anatomy
Undergraduate 3
05/20/2011

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Cards

Term
What is the epithelium connected to?
Definition
Basement membrane
Term
How is epithelium anchored to B.M?
Definition
transmembrane integrins are bound to proteoglycan and collagen by GLYCOPROTEINS
Term
How is the B.M secreted?
Definition
by both CT and epithelial layer
Term
What is the first heirarchy of CT classification?
Definition
Proper and Special
Term
What kinds of proper CT are there?
Definition
Dense and Loose CT
Term
What is the difference between dense and loose CT?
Definition

dense CT has more collagen fibers than cells

loose CT has more cells than fibers

Term
What are two types of dense CT?
Definition

regular (striated, parallel arrange of fibers)

irregular (random arrangement of fibers)

Term
Role of loose CT?
Definition

Site of inflammation, allergic rxn

Battlefield for bacteria, antigens

Term
True / False: Elastic CT is dense CT
Definition
False, Loose CT
Term
Where is dense, irregular CT found?
Definition
capsules of organs, dermis
Term
where is dense, regular CT found?
Definition
tendons/ligaments
Term
What are the roles of fibroblast?
Definition
secrete fibers, and ECM
Term
List characteristics of fibroblast
Definition

Elongated (diamond shape) cell

Spherical nucleus

Euchromatin and abundant RER

Term
In active phase, fibrocyte cytplasm is...
Definition

acidic (basophilic)

 

Term
Inactive fibroblasts have a basic or acidic cytoplasm?
Definition
basic (acidophilic)
Term
Name the heirarchy of molecules that make up a tendon
Definition

Tendon

Fiber

Fibril

tropcolagen

Procollagen

Term

Describe collagen synthesis

 

Definition
  1. DNA transcribed in nucleus
  2. mRNA translated in RER to form pre-procollagen
  3. pre-procollagen modified in RERto form procollagen
  4. propeptides added to procollagen to prevent spontaneous formation inside cell
  5. procollagen exported to ECM, and propeptinase cleaves propeptides to allow formation of tropocollagen
Term
Elastic CT is part of which CT class?
Definition
Proper, Loose
Term
Describe elastic CT
Definition

Many elastic fibers

Provide elasticity to tissue

Term
Describe composition of elastic fiber
Definition
Made up of an elastin core, surrounded by microfibrils
Term
Reticular CT is made up predominantly of what?
Definition
Collagen type III
Term
What types of Proper, loose CT are there?
Definition
Adipose, Elastic, Reticular
Term
Role of mast cells?
Definition
Produce and store histamine heparin (allergic rxn and inflammation)
Term
Where are mast cells found? Describe appearance
Definition

found near arteries

Spherical nuc, granules

Term
Role of plasma cells
Definition

Secrete antibodies

 

Term
What cell derives plasma cell?
Definition
B lymphocytes
Term
Mast cells are derived from which cell?
Definition
Bone marrow stem cell
Term
Desribe shape of plasma cell
Definition

Pale region around nucleus

very round nucleus

Looks like mast cell except no granules

Term
Macrophages role?
Definition

Remove cellular debris,

Protection from foreign invaders

Production of cytokenes, growth factors

Term
What cell derives macrophages?
Definition
Monocyte
Term
Shape of macrophage?
Definition

Pseudopodia (protrusions)

Rough "hairy" surface

Indented nucleus

Term
Difference between white and brown adipose
Definition

White: subcutaneous layer, Brown=Neck, interscapular

White=contain receptors that regulate uptake of fatty acid

Brown more vascularized

Brown has more mitochondria

Brown more metabolically active

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